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Background:
Systematic Review

Are There Benefits of Total Hip Arthroplasty with Dual-Mobility Cups Compared to Bipolar Hemiarthroplasty for Femoral Neck Fractures in the Geriatric Population? A Systematic Review and Meta-Analysis of Comparative Studies

by
Dimitrios Grammatikopoulos
,
Vasileios F. Pegios
,
Stavros Tsotsolis
,
Eustathios Kenanidis
and
Eleftherios Tsiridis
*
Academic Orthopaedic Department, Aristotle University Medical School, General Hospital Papageorgiou, Ring Road Efkarpia, 56403 Thessaloniki, Greece
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2025, 14(14), 5076; https://doi.org/10.3390/jcm14145076
Submission received: 24 June 2025 / Revised: 13 July 2025 / Accepted: 14 July 2025 / Published: 17 July 2025
(This article belongs to the Special Issue The “Orthogeriatric Fracture Syndrome”—Issues and Perspectives)

Abstract

Background/Objectives: The optimal treatment for femoral neck fractures (FNFs) in the elderly remains unclear. Internal fixation, bipolar hip hemiarthroplasty (BH), standard total hip arthroplasty (THA), or dual mobility (DM-THA) cups have been employed, each presenting various advantages and disadvantages. This systematic review and meta-analysis evaluated comparative studies of BH and DM-THA in FNFs among the elderly, aiming to ascertain differences in outcomes, including functional recovery, patient-reported outcome measures, implant survival, complications, and mortality rates. Methods: This meta-analysis followed PRISMA 2020 guidelines with a pre-registered PROSPERO protocol (CRD420251065762). A comprehensive search of electronic databases and grey literature included only comparative studies of BH and DM-THA in patients over 65 years with FNFs. Results: Sixteen studies were eligible, comprising four randomised controlled trials and twelve retrospective comparative studies involving 11,460 patients (10,036 BH; 1424 DM-THA). Patients with DM-THA exhibited a higher postoperative Harris Hip Score (4.55, p < 0.0001), alongside a lower dislocation risk ([OR] 2.77, p < 0.0001), a reduced revision rate ([OR] 2.36, p < 0.0001), and decreased mortality ([OR] 1.94, p < 0.0001). The operative time was somewhat longer in the DM-THA group, by 12.71 min, and blood loss was greater by 121 mL, indicating significant heterogeneity across the studies. Conclusions: DM-THA for FNFs in elderly patients results in improved functional recovery and lower dislocation, reoperation, and mortality risk. However, longer operative times and increased blood loss remain significant considerations. Further, well-designed comparative studies are required to evaluate overall cost-effectiveness and define the optimal age threshold, beyond which the limitations of DM-THA may outweigh its benefits.

1. Introduction

Femoral neck fractures (FNFs) are among the most prevalent fractures in older adults, usually due to low-energy falls from a standing position [1,2]. Their prevalence in Western populations has seen a surge in recent years [3]. FNFs pose a serious threat, particularly considering the already compromised health of elderly patients, potentially leading to multiple complications and a high mortality risk, which may be as high as 20% within the first year following the injury [1,2].
Elderly patients with displaced FNFs, especially those over 75, have often undergone hip hemiarthroplasty (HA) [4]. This procedure involves substituting the fractured femoral head with a prosthetic stem and head, keeping the native acetabulum intact. For decades, bipolar heads have been recognised as the gold standard in hip HA, offering improved range of motion, greater stability, and lower dislocation risk compared to earlier unipolar models [5,6,7]. Total hip arthroplasty (THA) has typically been reserved for patients aged 65 to 75, although the primary factors influencing the choice of surgery are patient comorbidities and overall health [8,9,10].
Dual mobility (DM) cups are a well-established concept in THA and resemble the bipolar hemiarthroplasty (BH). These cups contain a large polyethylene bearing that encases a smaller femoral head, like the BH, which moves within a metal shell in the acetabular cup, allowing an additional degree of movement [11,12,13]. While DM cups are utilised in both primary and revision THA, they are often chosen to address hip instability, particularly for patients with severe hip dysplasia, spinopelvic imbalances, neuromuscular disorders, or cognitive disabilities [11,14].
Considering these advantages, there has been growing interest in using Dual Mobility Total Hip Arthroplasty (DM-THA) to manage displaced FNFs as a viable alternative to the established BH. This interest is driven by a demographic shift towards a more active elderly population that necessitates enhanced functional recovery and more durable implants. The principal advantage of DM cups in this population is their heightened hip stability, especially in light of recent research demonstrating an increase in revision rates for BH [15,16]. Furthermore, reducing the frequency of revision surgeries can significantly alleviate the long-term socioeconomic burden of these injuries [17,18]. Direct comparisons between these two procedures in the past have highlighted these potential benefits of DM-THA [19]. Conversely, prevailing concerns regarding increased operative time, blood loss, length of hospital stay, and upfront costs remain for this population [20]. The optimal surgical approach for the geriatric population with FNFs remains uncertain, as does the age threshold beyond which the implementation of DM cups fails to yield additional benefits.
This systematic review and meta-analysis aimed to ascertain differences in outcomes, including functional recovery, patient-reported outcome measures (PROMs), implant survival, complication and mortality rates, and the need for revision surgeries between bipolar BH and DM-THA for displaced FNFs in elderly patients, focusing solely on comparative studies of these two treatment types.

2. Materials and Methods

2.1. Literature Search Strategy

This systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA 2020) [21] statement and in line with the protocol agreed to by all authors. A PRISMA checklist is included in Supplementary Materials S1. The review protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO) under registration number CRD420251065762. Studies were identified by searching the PubMed database, ScienceDirect, and the Cochrane Library (end of search date: June 2025) by two reviewers (DG, ST). The following search terms, along with the appropriate MeSH terms, while employing Boolean operators, were used: -(((((dual mobility [Title/Abstract]) OR (DM[Title/Abstract])) OR (Tripolar [Title/Abstract])) OR (acetabular component [Title/Abstract])) OR (cup [Title/Abstract])) OR (“Arthroplasty, Replacement, Hip”[Mesh])-((((“Hemiarthroplasty”[Mesh]) OR (bipolar [Title/Abstract])) OR (hemiarthroplasty*[Title/Abstract])) OR (partial hip [Title/Abstract])) OR (hemi [Title/Abstract])-((((((((“Hip Fractures”[Mesh])) OR (intracapsular fracture*[Title])) OR (hip fracture*[Title])) OR (neck fracture*[Title])) OR (non-elective [Title])) OR (femoral [Title])) OR (femur [Title]))-(((((((comparative [Title/Abstract]) OR (comparison [Title/Abstract])) OR (outcome*[Title/Abstract])) OR (risk [Title/Abstract])) OR (survival [Title/Abstract])) OR (assessment [Title/Abstract])) OR (“Treatment Outcome”[Mesh])) OR (“Treatment Expectations”).
The exact search string that was used is presented in Supplementary Materials S2. The reference lists of relevant published articles were manually searched to identify any missing records. All identified citations were imported into Zotero [22] for reference management. After removing duplicates, three reviewers (DG, ST, VP) independently screened the titles and abstracts to identify potentially eligible studies. Studies that appeared to meet the inclusion criteria or those for which eligibility could not be determined from the abstract were retrieved in full text. Discrepancies during the selection process were resolved through discussion, and if consensus was not achieved, a fourth senior reviewer (EK) was consulted.

2.2. Inclusion and Exclusion Criteria

Eligible studies were required to be randomised controlled trials (RCT) or comparative observational studies, both prospective and retrospective, involving adult patients aged 18 years or older with displaced intracapsular FNFs. The intervention of interest was BH, while the comparator was DM-THA. Studies needed to report at least one relevant comparative clinical outcome, including dislocation rate, reoperation rate, mortality rate, or functional scores such as the Harris Hip Score. We excluded studies that involved only monopolar HA or conventional THA without DM components, as well as case reports, editorials, animal or cadaveric studies, and articles that lacked full-text availability or were not published in English.

2.3. Data Extraction

Two reviewers independently extracted data from each included study using a standardised data collection form. The extracted information encompassed study design, year of publication, sample size, patient demographics (age and sex), type of surgical intervention (BH or DM-THA), fixation method, duration of follow-up, and reported clinical outcomes. These outcomes included blood loss, dislocation rates, revision surgeries, mortality, and functional scores. Any discrepancies in data extraction were resolved through full-text discussions among all reviewers. No unresolved disagreements arose during this process.

2.4. Risk of Bias and Study Quality Assessment

Two reviewers (DG and ST) independently evaluated the methodological quality and risk of bias of each included study using the Cochrane Risk of Bias 2 assessment tool (RoB2) for randomised controlled trials [23] and the Newcastle–Ottawa Scale (NOS) for retrospective cohort studies [24]. The evaluation focuses on selection bias, comparability, and assessment of outcome measures. The results of the quality assessment are exhibited in Supplementary Materials S3 and S4, respectively. Any disagreements were resolved by consulting a senior reviewer (EK).

2.5. Statistical Analysis

Six meta-analyses were performed, one for each of the following comparative outcomes between BH and DM-THA patients: (i) operative time, (ii) estimated blood loss, (iii) postoperative Harris Hip Score, (iv) dislocation rate, (v) reoperation rate, and (vi) mortality rate. For the outcomes based on continuous variables (i, ii, iii), a random effects model with inverse-variance weighting for estimation of mean difference was implemented. The confidence interval (CI) was set at 95%. Five studies did not provide data for the standard deviation. Based on the nature of the studied variables and on data from the remaining studies, it was assumed that these data followed a normal distribution. Consequently, a standard deviation was imputed based on the mean value of the standard deviations of the remaining included studies. For the outcomes that contained dichotomous data (iv, v, vi), a random effects model with inverse-variance weighting was employed, and the odds ratio (OR) was used as an effect measure with a 95% confidence interval. The I2 statistic assessed heterogeneity. All data analyses were conducted using Review Manager (RevMan) Version 5.4., Copenhagen, The Cochrane Collaboration, 2020 [25].

3. Results

3.1. Search Results

The initial search identified a total of 1103 studies. After removing duplicates, 976 studies were screened, and 884 of these were excluded based on their titles and abstracts. The full texts of the remaining 92 studies were evaluated comprehensively. Ultimately, 16 studies [26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41] were deemed suitable for inclusion in both the qualitative and quantitative syntheses. A PRISMA flow diagram illustrating the study screening and selection process is depicted in Figure 1. The studies that were excluded after full-text evaluation, along with the reasons for their exclusion, are displayed in Supplementary Materials S4.

3.2. Included Studies Design and Patient Demographics

The included studies were published between 2014 and 2025. Twelve of these were retrospective comparative studies [26,27,28,29,30,33,35,36,37,38,39,41], while the remaining four were randomised controlled trials [31,32,34,40]. All studies featured at least two subgroups of patients who underwent surgical treatment for an FNF, either with bipolar HA or with THA with a DM cup, and two or more comparative outcomes between these two subgroups were assessed. A total of 11,460 patients across sixteen studies were included in the analysis; 10,036 patients were treated with BH and 1424 patients with DM-THA. The average ages of patients in the BH and DM-THA subgroups were 79.3 and 76.5 years, respectively, at the time of surgery. The percentage of male patients who underwent BH was 32.9%, whereas the percentage of male patients who underwent DM-THA was 30.7% (Table 1).

3.3. Studied Outcomes and Follow-Up

Seven studies [26,27,29,32,34,40,41] provided data on the estimated blood loss during the operation for each treatment group. Fifteen, 10, and 13 studies examined dislocation rates [26,27,28,29,31,32,33,34,35,36,37,38,39,40,41], reoperation rates [26,27,28,31,32,33,35,38,39,41], and mortality rates [26,27,28,29,30,31,32,35,36,37,38,40,41] between the groups, respectively. Eight studies measured the postoperative Harris Hip Scores for each group [29,30,32,33,34,39,40,41]. Follow-up varied across studies, ranging from 6 to 62 months. However, 14 studies included a minimum follow-up of 12 months for both groups of patients [26,27,28,29,30,31,32,33,34,35,36,38,40,41] (Table 2).

3.4. Operative and Implant Characteristics

All but one study provided information on the surgical approach. A variety of approaches were employed, with the posterolateral approach being the most common. The direct anterior approach, the anterolateral approach, and the direct lateral approach were also utilised in some of the studies [27,30,31,36,39,40]. Eleven studies reported the mean operative time for each type of surgery [26,27,28,29,31,32,34,37,39,40,41]. Furthermore, most studies reported the type of implants used and the type of fixation for the femoral stem in both procedures, the acetabular component for DM-THA, and other technical aspects of the operations. The allocation of patients to each type of surgical treatment varied based on study design and institution-specific protocols. These details are summarised in Table 3.

3.5. Cognitive and Neuromuscular Status of Patients in the Included Studies

Nine studies assessed the cognitive and neuromuscular status of the included patients at the time of surgery [28,29,31,32,33,35,36,38,39,41]. Specifically, three studies excluded all patients with either cognitive impairment or a neuromuscular deficit that could affect walking ability [29,39,41]. Conversely, two studies included only patients diagnosed with cognitive impairment or a neuromuscular disorder [33,36]. Finally, the study by Iorio et al. included only patients diagnosed with dementia, but not with a neuromuscular disorder [31]. A diagnosis of cognitive impairment involved Alzheimer’s disease or other dementias, and systemic CNS atrophy. Neuromuscular disorders comprised Parkinson’s disease, myasthenia gravis, other myopathies, epilepsy, and multiple sclerosis (Table 4).

3.6. Outcomes

Six meta-analyses were performed, one each for the following comparative outcomes between BH and DM-THA patients:
(i)
Operative time
The average length of the operation for each group was reported in 11 studies [26,27,28,29,31,32,34,37,39,40,41]. As expected, the operative time was higher for DM-THA in every study. However, there were disparities regarding the mean difference in surgical time between the two procedures, with two studies displaying an increase of only 6 min [26,27,28,29,30,31,32]. In contrast, in the study by Makeen et al., the duration of surgery increased by 29 min when performing a DM-THA [34]. The overall mean difference was statistically significant (12.71, 95% CI: 8.68 to 16.75, p < 0.0001). The I2 index was 75% (Figure 2).
(ii)
Estimated blood loss
Seven studies recorded data on the average estimated blood loss during surgery [26,27,29,32,34,40,41]. Similarly to operative time, DM-THA averaged a higher volume of intraoperative blood loss compared to BHA, as was anticipated, yet the difference in the estimated amount of blood that was lost between BHA and DM-THA exhibited considerable variability among studies, with studies reporting mean differences as low as 19 mL [32] and as high as 332 mL [27]. The overall mean difference was statistically significant (121.00, 95% CI: 76.54 to 165.46, p < 0.0001). The heterogeneity of the studies was considerable (I2 = 92%) and statistically significant (Figure 3).
(iii)
Postoperative Harris Hip Score (HHS)
Eight studies utilised the HHS to evaluate the functional status of the patients at various postoperative intervals [29,30,32,33,34,39,40,41]. For this analysis, the results of the HHS that were recorded during the last follow-up evaluation were used. In all studies but one [33], the mean HHS was higher in DM-THA patients. The overall mean difference was statistically significant (4.55, 95% CI: 2.45 to 6.65, p < 0.0001), with an I2 index of 71% (Figure 4).
(iv)
Dislocation rate
The comparative postoperative dislocation rates between groups were addressed in 15 studies [26,27,28,29,31,32,33,34,35,36,37,38,39,40,41]. For studies providing dislocation rates at various time points, the dislocation rate at the last follow-up was included in the analysis, except for one study with a very long follow-up period, where the dislocation rate at 2 years postoperatively was used instead [35]. In two studies, no dislocations occurred in either group [27,39]. Only one study with a small sample size demonstrated equal rates of dislocations between groups [34]; in the remaining 12 studies, the dislocation rate was higher in the BH group. In our meta-analysis, BH was associated with a statistically significant increase in risk of dislocation ([OR] 2.77, 95% CI: 1.81 to 4.24, p < 0.0001), with minimal heterogeneity (I2 = 0%) (Figure 5).
(v)
Reoperation rate
Ten studies examined the all-purpose reoperation rate during the follow-up period [26,27,28,31,32,33,35,38,39,41]. The most common causes for reoperation included dislocation, surgical site infection, periprosthetic fracture, and aseptic loosening. The study by Pala et al. found a higher reoperation rate in the DM-THA group [39]. In the remaining nine studies, patients who underwent BH were reoperated on at a higher rate. The odds ratio for reoperation in the BH group was estimated at ([OR] 2.36, 95% CI: 1.61 to 3.47, p < 0.0001) and was statistically significant, with minimal heterogeneity (I2 = 0%) (Figure 6).
(vi)
Mortality rate
Thirteen studies assessed the postoperative mortality rates for each treatment group [26,27,28,29,30,31,32,35,36,37,38,40,41]. Ten studies provided data on 1-year mortality [26,27,28,29,30,31,32,33,34,36,38,39,41]. For the remaining studies, the available mortality rates at 6 months, 2 years, and 5 years, respectively, after the operation were used in our analysis. A single study showed a higher mortality rate in the DM-THA group [29], and another presented equal rates between the groups [40]. The remaining 11 studies demonstrated higher postoperative mortality for BH patients. Overall, a statistically significant increase in mortality risk for the BH group was found ([OR] 1.94, 95% CI: 1.28 to 2.92, p < 0.0001). The I2 index was 62% (Figure 7).

4. Discussion

This systematic review and meta-analysis aimed to evaluate treatment outcomes between bipolar hip HA and DM-THA in patients with FNFs by analyzing all observational studies and randomised controlled trials in the literature that included and directly compared groups of patients treated with either of these two methods. Our results suggest that DM-THA provides superior outcomes in terms of postoperative functionality, pain, quality of life, and return to preoperative activity levels. Simultaneously, DM-THA presents a significantly reduced risk of long-term complications, including mortality. Conversely, it may be linked to higher perioperative morbidity due to the prolonged duration of the operation and increased blood loss during surgery. Both factors and their consequences (i.e., blood transfusion, aggressive fluid management, delayed/impaired postoperative mobilisation) are well-recognised predictors of short-term complications, such as surgical site infection and several adverse medical events [42,43,44,45,46].
It is thus apparent that the benefits of each treatment method do not always outweigh their risks and vice versa. This fact raises the question of whether these patients could be stratified based on specific criteria that would enable patient-tailored treatment. Age and pre-injury activity level are usually the most important parameters determining allocation to a treatment method in most institutions worldwide [47,48]. Traditionally, conventional THA has been the preferred treatment for younger active patients, and the age threshold for THA has increased in recent years [49,50]. However, conventional THA has been linked to a higher dislocation rate compared to HA, even in patients with similar characteristics [20,51,52,53]. On the contrary, not only has DM-THA shown a lower dislocation rate than conventional THA in the treatment of FNFs [15,54], but it has also, according to our study, demonstrated a significantly lower risk of dislocation compared to bipolar HA. This finding is notable because DM-THA could potentially bridge a “treatment gap” in patient groups where conventional THA would significantly raise the risk of dislocation, but HA would impede daily activities and diminish quality of life.
Another key factor to consider when deciding which procedure to choose is the presence of cognitive impairment or neuromuscular disease. These individuals are characterised by compromised stability and walking ability, making them prone to postoperative delirium, all of which are associated with an increased risk of falls that could lead to dislocation, peri-prosthetic fracture, and higher mortality [55,56]. Three of the studies included in our analysis (two RCTs and one registry-based retrospective cohort study) were conducted exclusively on patients suffering from cognitive impairment without neuromuscular deficit [31] or a combination of patients diagnosed with either cognitive impairment or a neuromuscular disorder [33,36]. All studies reported similar or favourable outcomes for DM-THA concerning dislocation, reoperation, and mortality rates. These results further enhance the status of DM-THA as a viable alternative to HA in this frail group of patients [57].
Individual anatomical characteristics of each patient represent another potential deciding factor in opting for DM-THA over HA. Acetabular deformities, such as a shallow acetabular socket or posterior wall deficiency, have been associated with a significantly increased risk of dislocation following HA [58,59]. Because these dislocations stem from the patient’s inherent hip morphology, they are often recurrent and typically require revision surgery. Additionally, other severe complications that may necessitate reoperation, such as acetabular prosthetic protrusion [60], can also occur. Therefore, DM-THA, by better replicating normal hip anatomy, could offer a safer option for most patients with dysplastic hips. DM-THA should also be considered for patients with preexisting osteoarthritis due to the risk of erosion of the acetabular cartilage and the consequent need for revision [61]. However, it is important to note that in the studies included in our review, revision surgery for the aforementioned cause in HA patients was an exceedingly rare complication, likely due to the short life expectancy of these patients, which suggests that THA is not a significant improvement in that aspect for older individuals.
As previously mentioned, a valid concern with DM-THA is the prolonged duration of surgery and the higher volume of blood loss. This is to be expected because DM-THA involves the additional surgical steps of preparation of the acetabular socket and insertion of the acetabular component. Nevertheless, there were discrepancies in our meta-analysis regarding these parameters. In some studies, the mean differences in operative time [26,32,39,41] and estimated blood loss [32,41] were minimal and likely without clinical significance. This observation suggests that these variables largely depend on the surgical team and could be minimised. Admittedly, most operations on hip fracture patients worldwide are carried out by orthopaedic surgeons without specialised training in hip arthroplasty. Hip HA has also been established as the standard of care for decades, before the surge of THA in recent years. Hence, most orthopaedic surgeons handle a considerably higher volume of HAs and are more familiar with them than THA, particularly DM-THA [62]. Therefore, surgeons involved in these procedures must undergo rigorous training in the assessment and placement of the acetabular component, as well as the proper handling of periacetabular soft tissues. Preoperative templating, educating the entire operating room staff, and cooperation with the anesthesiologists could further mitigate these issues. In any case, DM-THA could be a very beneficial solution with negligible risks when performed by a skilled and experienced surgeon.
A previous systematic review and meta-analysis on comparative outcomes of BH and DM-THA was conducted in 2021 by Ma et al. [19], exhibiting similar results to those of our research for all outcomes. Age, female sex, posterolateral surgical approach, and implant choice showed no link to dislocation or reoperation [19]. The addition of eight newer studies [34,35,36,37,38,39,40,41], including two RCTs [34,40], enhances the consistency and reliability of these findings to a greater extent.
Our study had limitations. Although this was the largest systematic review and meta-analysis to date, with studies that directly compared outcomes of BH and DM-THA, only four [31,32,34,40] out of 16 studies were randomised controlled trials, which were evaluated at moderate [31,40] or high risk [32,34] of bias according to the ROB2 assessment tool. The remaining 12 [26,27,28,29,30,33,35,36,37,38,39,41] were observational studies, and they contributed the majority of patients to our analysis. Indeed, most of these studies comprised highly heterogeneous groups of patients. Furthermore, the meta-analyses on certain outcomes were characterised by significant heterogeneity. The average age of BH patients was only 2.8 years higher than that of DM-THA patients across all studies, but these patients were likely still subject to selection bias by possibly being assigned to a treatment method based on their overall health profile and preinjury activity levels. As previously noted, the rationale for allocation to treatment groups also varied considerably among studies. It should be remarked, however, that in several of the retrospective studies, patients were not allocated to a treatment method based on patient-related factors, such as age and comorbidities, but rather according to different institutional protocols for separate time periods, or in the case of a multicentre study, varying treatment protocols between institutions during the same period. This process introduced a form of quasi-randomisation in patient selection, thereby reducing overall selection bias. Other variables, such as surgical approach and technique, fixation method, varying implants, varying follow-up periods and differing surgeons, even within the same study, all represent significant confounding factors that could influence our results substantially and contribute to the high heterogeneity that was observed in several meta-analyses. Moreover, the inclusion of studies focusing on special subgroups of patients (i.e., cognitively impaired and neuromuscular deficient individuals) alongside studies that consisted solely of self-sufficient patients and others that did not address these concerns at all further reduces the generalisability of our findings. Additionally, the meta-analysis for reoperation rate, despite displaying overwhelmingly favourable results for DM-THA without heterogeneity, did not distinguish between minor and major causes and subsequent reoperation procedures.

5. Conclusions

Our study indicates that DM-THA for the treatment of FNFs offers a reliable and safe alternative to BH, providing better functional results and a lower risk of long-term complications in certain subgroups of patients. However, current evidence is characterised by substantial limitations, rendering it insufficient to recommend the procedure for specific groups. Thus, there are no practical clinical criteria provided to guide when one procedure should be preferred over the other. More RCTs and propensity-score-matched observational studies, involving a larger number of patients and separate groups by age, mental status, and functionality, should be conducted to draw more robust conclusions. Nonetheless, in modern clinical practice, DM-THA should be taken into consideration as a potential option for the treatment of FNF patients after carefully accounting for their individual characteristics.

Supplementary Materials

The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/jcm14145076/s1, Supplementary Material S1: The PRISMA 2020 Checklist, Supplementary Material S2: The search string used in our study, Supplementary Material S3: Quality assessment for randomised control trials included, based on the Cochrane Risk of Bias Assessment 2 Tool (RoB 2), Supplementary Material S4: Quality assessment for cohort studies included, based on the Newcastle-Ottawa-Scale (NOS). Supplementary Material S5. Studies excluded after full-text assessment; Supplementary Material S6. Implant companies in the included studies.

Author Contributions

Conceptualisation, D.G. and E.K.; methodology, D.G. and E.K.; formal analysis, D.G., E.K., V.F.P. and S.T.; investigation, D.G., E.K., V.F.P. and S.T.; writing—original draft preparation, D.G., E.K., V.F.P. and S.T.; writing—review and editing, D.G., E.K., V.F.P., S.T. and E.T.; supervision, E.K. and E.T.; All authors have read and agreed to the published version of the manuscript.

Funding

This research received no external funding.

Institutional Review Board Statement

The review protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO) under registration number CRD420251065762 (9 June 2025).

Informed Consent Statement

Not applicable.

Data Availability Statement

The dataset is available upon request from the authors.

Conflicts of Interest

The authors declare no conflicts of interest.

Abbreviations

The following abbreviations are used in this manuscript:
FNFFemoral Neck Fracture
HAHip Hemiarthroplasty
THATotal Hip Arthroplasty
DMDual Mobility
BHBipolar Hip Hemiarthroplasty
DM-THADual Mobility Total Hip Arthroplasty
PROMsPatient Reported Outcome Measures
RCTRandomised Controlled Trials
RoB2Cochrane Risk of Bias 2 assessment tool
NOSNewcastle-Ottawa Scale
CIConfidence Interval
OROdds Ratio
HHSHarris Hip Score

References

  1. Xu, D.-F.; Bi, F.-G.; Ma, C.-Y.; Wen, Z.-F.; Cai, X.-Z. A Systematic Review of Undisplaced Femoral Neck Fracture Treatments for Patients over 65 Years of Age, with a Focus on Union Rates and Avascular Necrosis. J. Orthop. Surg. Res. 2017, 12, 28. [Google Scholar] [CrossRef] [PubMed]
  2. Sheikh, H.Q.; Hossain, F.S.; Aqil, A.; Akinbamijo, B.; Mushtaq, V.; Kapoor, H. A Comprehensive Analysis of the Causes and Predictors of 30-Day Mortality Following Hip Fracture Surgery. Clin. Orthop. Surg. 2017, 9, 10. [Google Scholar] [CrossRef] [PubMed]
  3. Moldovan, F.; Moldovan, L. A Modeling Study for Hip Fracture Rates in Romania. J. Clin. Med. 2025, 14, 3162. [Google Scholar] [CrossRef] [PubMed]
  4. Chen, J.; She, G.; Luo, S.; Wu, W.; Zhuang, T.; Huan, S.; Liu, N.; Zha, Z. Hemiarthroplasty Compared with Internal Fixation for Treatment of Nondisplaced Femoral Neck Fractures in Elderly Patients: A Retrospective Study. Injury 2020, 51, 1021–1024. [Google Scholar] [CrossRef] [PubMed]
  5. Beauchamp-Chalifour, P.; Pelet, S.; Belhumeur, V.; Angers-Goulet, M.; Bédard, L.; Belzile, E.L. Should We Use Bipolar Hemiarthroplasty in Patients ≥70 Years Old with a Femoral Neck Fracture? A Review of Literature and Meta-Analysis of Randomized Controlled Trials. J. Arthroplast. 2022, 37, 601–608. [Google Scholar] [CrossRef] [PubMed]
  6. Filippo, M.; Driessen, A.; Colarossi, G.; Quack, V.; Tingart, M.; Eschweiler, J. Bipolar versus Monopolar Hemiarthroplasty for Displaced Femur Neck Fractures: A Meta-Analysis Study. Eur. J. Orthop. Surg. Traumatol. 2020, 30, 401–410. [Google Scholar] [CrossRef] [PubMed]
  7. Imam, M.A.; Shehata, M.; Abdallah, A.R.; Ahmed, H.; Kader, N.; Ernstbrunner, L.; Narvani, A.A.; Kambouroglou, G.; Mcnamara, I.; Sallam, A.A. Unipolar versus Bipolar Hemiarthroplasty for Displaced Femoral Neck Fractures: A Pooled Analysis of 30,250 Participants Data. Injury 2019, 50, 1694–1708. [Google Scholar] [CrossRef] [PubMed]
  8. Yoo, J.-I.; Jang, S.-Y.; Cha, Y.; Choy, W.-S.; Koo, K.-H. Comparison of Mortality, Length of Hospital Stay and Transfusion between Hemiarthroplasty and Total Hip Arthroplasty in Octo- and Nonagenarian Patients with Femoral Neck Fracture: A Nationwide Study in Korea. J. Korean Med. Sci. 2021, 36, e300. [Google Scholar] [CrossRef] [PubMed]
  9. Peng, W.; Bi, N.; Zheng, J.; Xi, N. Does Total Hip Arthroplasty Provide Better Outcomes than Hemiarthroplasty for the Femoral Neck Fracture? A Systematic Review and Meta-Analysis. Chin. J. Traumatol. 2020, 23, 356–362. [Google Scholar] [CrossRef] [PubMed]
  10. Wang, Z.; Bhattacharyya, T. Outcomes of Hemiarthroplasty and Total Hip Arthroplasty for Femoral Neck Fracture: A Medicare Cohort Study. J. Orthop. Trauma 2017, 31, 260–263. [Google Scholar] [CrossRef] [PubMed]
  11. Patil, N.; Deshmane, P.; Deshmukh, A.; Mow, C. Dual Mobility in Total Hip Arthroplasty: Biomechanics, Indications and Complications–Current Concepts. Indian J. Orthop. IJOO 2021, 55, 1202–1207. [Google Scholar] [CrossRef] [PubMed]
  12. Castiello, E.; Moghnie, A.; Tigani, D.; Affatato, S. Dual Mobility Cup in Hip Arthroplasty: An In-depth Analysis of Joint Registries. Artif. Organs 2022, 46, 804–812. [Google Scholar] [CrossRef] [PubMed]
  13. De Martino, I.; Triantafyllopoulos, G.K.; Sculco, P.K.; Sculco, T.P. Dual Mobility Cups in Total Hip Arthroplasty. World J. Orthop. WJO 2014, 5, 180. [Google Scholar] [CrossRef] [PubMed]
  14. Heckmann, N.; Weitzman, D.S.; Jaffri, H.; Berry, D.J.; Springer, B.D.; Lieberman, J.R. Trends in the Use of Dual Mobility Bearings in Hip Arthroplasty. Bone Jt. J. 2020, 102-B, 27–32. [Google Scholar] [CrossRef] [PubMed]
  15. Santiago, M.S.; Akbarpoor, F.; Aidar, F.J.; Neto, J.M.S.; De Matos Pereira Silva, M.V.V.; Darwish, S.; Khokar, M.A.; Ahmed, Z.; Zamora, F.V.; Madruga, R.E.T.T.; et al. Outcomes of Dual Mobility versus Conventional Total Hip Arthroplasty for Patients with Femoral Neck Fractures: A Systematic Review and Meta-Analysis Including Registry Data. J. Orthop. Surg. Res. 2025, 20, 405. [Google Scholar] [CrossRef] [PubMed]
  16. Bloemheuvel, E.M.; van Steenbergen, L.N.; Swierstra, B.A.; Schreurs, B.W. Revision Risk of Unipolar and Bipolar Hemiarthroplasties in the Dutch Arthroplasty Register. J. Arthroplast. 2024, 39, 118–123. [Google Scholar] [CrossRef] [PubMed]
  17. Ravi, B.; Pincus, D.; Khan, H.; Wasserstein, D.; Jenkinson, R.; Kreder, H.J. Comparing Complications and Costs of Total Hip Arthroplasty and Hemiarthroplasty for Femoral Neck Fractures: A Propensity Score-Matched, Population-Based Study. J. Bone Jt. Surg. 2019, 101, 572–579. [Google Scholar] [CrossRef] [PubMed]
  18. Burgers, P.T.P.W.; Hoogendoorn, M.; Van Woensel, E.A.C.; Poolman, R.W.; Bhandari, M.; Patka, P.; Van Lieshout, E.M.M. Total Medical Costs of Treating Femoral Neck Fracture Patients with Hemi- or Total Hip Arthroplasty: A Cost Analysis of a Multicenter Prospective Study. Osteoporos. Int. 2016, 27, 1999–2008. [Google Scholar] [CrossRef] [PubMed]
  19. Ma, H.-H.; Chou, T.-F.A.; Pai, F.-Y.; Tsai, S.-W.; Chen, C.-F.; Wu, P.-K.; Chen, W.-M. Outcomes of Dual-Mobility Total Hip Arthroplasty versus Bipolar Hemiarthroplasty for Patients with Femoral Neck Fractures: A Systematic Review and Meta-Analysis. J. Orthop. Surg. Res. 2021, 16, 152. [Google Scholar] [CrossRef] [PubMed]
  20. Tang, X.; Wang, D.; Liu, Y.; Chen, J.; Zhou, Z.; Li, P.; Ning, N. The Comparison between Total Hip Arthroplasty and Hemiarthroplasty in Patients with Femoral Neck Fractures: A Systematic Review and Meta-Analysis Based on 25 Randomized Controlled Trials. J. Orthop. Surg. Res. 2020, 15, 596. [Google Scholar] [CrossRef] [PubMed]
  21. Page, M.J.; McKenzie, J.E.; Bossuyt, P.M.; Boutron, I.; Hoffmann, T.C.; Mulrow, C.D.; Shamseer, L.; Tetzlaff, J.M.; Akl, E.A.; Brennan, S.E.; et al. The PRISMA 2020 Statement: An Updated Guideline for Reporting Systematic Reviews. BMJ 2021, 372, n71. [Google Scholar] [CrossRef] [PubMed]
  22. Corporation for Digital Scholarship. Zotero, version 6.0.26, [Software] (Original Work Published 2006); Corporation for Digital Scholarship: Vienna, VA, USA, 2023. Available online: https://www.zotero.org/ (accessed on 15 June 2025).
  23. Sterne, J.A.C.; Savović, J.; Page, M.J.; Elbers, R.G.; Blencowe, N.S.; Boutron, I.; Cates, C.J.; Cheng, H.-Y.; Corbett, M.S.; Eldridge, S.M.; et al. RoB 2: A Revised Tool for Assessing Risk of Bias in Randomised Trials. BMJ 2019, 366, l4898. [Google Scholar] [CrossRef] [PubMed]
  24. Ottawa Hospital Research Institute. Available online: https://www.ohri.ca/programs/clinical_epidemiology/oxford.asp (accessed on 15 June 2025).
  25. RevMan. Available online: https://revman.cochrane.org/myReviews (accessed on 22 June 2025).
  26. Bensen, A.S.; Jakobsen, T.; Krarup, N. Dual Mobility Cup Reduces Dislocation and Re-Operation When Used to Treat Displaced Femoral Neck Fractures. Int. Orthop. SICOT 2014, 38, 1241–1245. [Google Scholar] [CrossRef] [PubMed]
  27. Ochi, H.; Baba, T.; Homma, Y.; Matsumoto, M.; Watari, T.; Ozaki, Y.; Kobayashi, H.; Kaneko, K. Total Hip Arthroplasty via the Direct Anterior Approach with a Dual Mobility Cup for Displaced Femoral Neck Fracture in Patients with a High Risk of Dislocation. SICOT-J. 2017, 3, 56. [Google Scholar] [CrossRef] [PubMed]
  28. Boukebous, B.; Boutroux, P.; Zahi, R.; Azmy, C.; Guillon, P. Comparison of Dual Mobility Total Hip Arthroplasty and Bipolar Arthroplasty for Femoral Neck Fractures: A Retrospective Case-Control Study of 199 Hips. Orthop. Traumatol. Surg. Res. 2018, 104, 369–375. [Google Scholar] [CrossRef] [PubMed]
  29. Kim, Y.T.; Yoo, J.-H.; Kim, M.K.; Kim, S.; Hwang, J. Dual Mobility Hip Arthroplasty Provides Better Outcomes Compared to Hemiarthroplasty for Displaced Femoral Neck Fractures: A Retrospective Comparative Clinical Study. Int. Orthop. SICOT 2018, 42, 1241–1246. [Google Scholar] [CrossRef] [PubMed]
  30. Fahad, S.; Nawaz Khan, M.Z.; Aqueel, T.; Hashmi, P. Comparison of Bipolar Hemiarthroplasty and Total Hip Arthroplasty with Dual Mobility Cup in the Treatment of Old Active Patients with Displaced Neck of Femur Fracture: A Retrospective Cohort Study. Ann. Med. Surg. 2019, 45, 62–65. [Google Scholar] [CrossRef]
  31. Iorio, R.; Iannotti, F.; Mazza, D.; Speranza, A.; Massafra, C.; Guzzini, M.; D’Arrigo, C.; Ferretti, A. Is Dual Cup Mobility Better than Hemiarthroplasty in Patients with Dementia and Femoral Neck Fracture? A Randomized Controlled Trial. SICOT-J. 2019, 5, 38. [Google Scholar] [CrossRef] [PubMed]
  32. Ukaj, S.; Zhuri, O.; Ukaj, F.; Podvorica, V.; Grezda, K.; Caton, J.; Prudhon, J.L.; Krasniqi, S. Dual Mobility Acetabular Cup Versus Hemiarthroplasty in Treatment of Displaced Femoral Neck Fractures in Elderly Patients: Comparative Study and Results at Minimum 3-Year Follow-Up. Geriatr. Orthop. Surg. Rehabil. 2019, 10, 2151459319848610. [Google Scholar] [CrossRef] [PubMed]
  33. Nonne, D.; Sanna, F.; Bardelli, A.; Milano, P.; Rivera, F. Use of a Dual Mobility Cup to Prevent Hip Early Arthroplasty Dislocation in Patients at High Falls Risk. Injury 2019, 50, S26–S29. [Google Scholar] [CrossRef] [PubMed]
  34. Makeen, T.M.; Abdelazim Mohamed, H.; Mohasseb, A.M.; Elshabrawy, W.E.S.A.E.; Ashoub, M.M.; El Ganzoury, I.M. Functional Outcome after Dual Mobility Cups Total Hip Replacement versus Bipolar Hemiarthroplasty in Femoral Neck Fractures in Active Elderly Patients: A Randomized Controlled Trial. Curr. Orthop. Pract. 2021, 32, 468–473. [Google Scholar] [CrossRef]
  35. Bertault-Le Gourrierec, J.; Cavaignac, E.; Berard, E.; Moretti, F.; Marot, V.; Chiron, P.; Reina, N. Comparative Study of Total Hip Arthroplasties with Dual Mobility Cups versus Hemiarthroplasties in Management of Femoral Neck Fractures: Survival and Dislocation Rate at 5 Years of Follow-Up? Orthop. Traumatol. Surg. Res. 2022, 108, 103098. [Google Scholar] [CrossRef] [PubMed]
  36. Cnudde, P.H.J.; Nåtman, J.; Hailer, N.P.; Rogmark, C. Total, Hemi, or Dual-Mobility Arthroplasty for the Treatment of Femoral Neck Fractures in Patients with Neurological Disease: Analysis of 9,638 Patients from the Swedish Hip Arthroplasty Register. Bone Jt. J. 2022, 104-B, 134–141. [Google Scholar] [CrossRef] [PubMed]
  37. Rotini, M.; Farinelli, L.; Natalini, L.; De Rosa, F.; Politano, R.; Cianforlini, M.; Pacetti, E.; Procaccini, R.; Magrini Pasquinelli, F.; Gigante, A. Is Dual Mobility Total Hip Arthroplasty Surgery More Aggressive than Hemiarthroplasty When Treating Femoral Neck Fracture in the Elderly? A Multicentric Retrospective Study on 302 Hips. Geriatr. Orthop. Surg. Rehabil. 2022, 13, 21514593221081375. [Google Scholar] [CrossRef] [PubMed]
  38. Valcarenghi, J.; Martinov, S.; Chahidi, E.; Jennart, H.; Bui Quoc, E.; Dimanche, M.C.; Hupez, A.; Bhogal, H.; Hafez, K.; Callewier, A.; et al. Hip Fractures Re-Operation Compared with Death at Two Year in Elderly Patients: Lowest Risk of Revision with Dual Mobility Total Hip Arthroplasty than with Bipolar Hemiarthroplasty or Internal Fixation of Garden I and II. Int. Orthop. SICOT 2022, 46, 1945–1953. [Google Scholar] [CrossRef] [PubMed]
  39. Pala, E.; Canapeti, J.; Trovarelli, G.; Berizzi, A.; Cerchiaro, M.C.; Zanarella, S.; Ruggieri, P. Dual Mobility Cup in Hip Fracture: Indications and Clinical Results Compared with Bipolar Hip Arthroplasty. Injury 2024, 55, 111483. [Google Scholar] [CrossRef] [PubMed]
  40. Heshmat, H.; Samir, W.; Abdel-Moneim, M.; Zakaria, Z.M. Management of Fracture Neck Femur in Elderly Patients Using Dual Mobility Cup Arthroplasty versus Bipolar Hemiarthroplasty. QJM Int. J. Med. 2024, 117, hcae175.670. [Google Scholar] [CrossRef]
  41. Xiao, K.; Liu, S.; Liang, B.; Li, S.; Liu, X.; Chen, J. Clinical Efficacy of THA with Dual Mobility Cup vs. Hemiarthroplasty in Elderly Patients with Femoral Neck Fracture: A Retrospective Study. Front. Surg. 2025, 12, 1507068. [Google Scholar] [CrossRef] [PubMed]
  42. Harris, T.; Segovia, N.; Koltsov, J.; Gardner, M. Association between Operative Duration and Adverse Outcomes after Hip Fracture Surgery: A NSQIP Matched Cohort Study. Injury 2024, 55, 111635. [Google Scholar] [CrossRef] [PubMed]
  43. Duchman, K.R.; Pugely, A.J.; Martin, C.T.; Gao, Y.; Bedard, N.A.; Callaghan, J.J. Operative Time Affects Short-Term Complications in Total Joint Arthroplasty. J. Arthroplast. 2017, 32, 1285–1291. [Google Scholar] [CrossRef] [PubMed]
  44. Surace, P.; Sultan, A.A.; George, J.; Samuel, L.T.; Khlopas, A.; Molloy, R.M.; Stearns, K.L.; Mont, M.A. The Association Between Operative Time and Short-Term Complications in Total Hip Arthroplasty: An Analysis of 89,802 Surgeries. J. Arthroplast. 2019, 34, 426–432. [Google Scholar] [CrossRef] [PubMed]
  45. Kim, J.L.; Park, J.-H.; Han, S.-B.; Cho, I.Y.; Jang, K.-M. Allogeneic Blood Transfusion Is a Significant Risk Factor for Surgical-Site Infection Following Total Hip and Knee Arthroplasty: A Meta-Analysis. J. Arthroplast. 2017, 32, 320–325. [Google Scholar] [CrossRef] [PubMed]
  46. Foss, N.B.; Kristensen, M.T.; Kehlet, H. Anaemia Impedes Functional Mobility after Hip Fracture Surgery. Age Ageing 2008, 37, 173–178. [Google Scholar] [CrossRef] [PubMed]
  47. Guyen, O. Hemiarthroplasty or Total Hip Arthroplasty in Recent Femoral Neck Fractures? Orthop. Traumatol. Surg. Res. 2019, 105, S95–S101. [Google Scholar] [CrossRef] [PubMed]
  48. Foote, C.J.; Soni, C.; Patel, S.P.; Moore, D.; Szatkowski, J. Factors That Influence Surgical Decision-Making for Geriatric Displaced Femoral Neck Fractures: Bullet Health Analysis (BHA) I: Worldwide Orthopaedic Research Collaboration: Leveraging Big Data (WORLD) I. Eur. J. Orthop. Surg. Traumatol. 2024, 34, 3005–3013. [Google Scholar] [CrossRef] [PubMed]
  49. Woon, C.Y.L.; Moretti, V.M.; Schwartz, B.E.; Goldberg, B.A. Total Hip Arthroplasty and Hemiarthroplasty: US National Trends in the Treatment of Femoral Neck Fractures. Am. J. Orthop. 2017, 46, E474–E478. [Google Scholar] [PubMed]
  50. Stronach, B.M.; Bergin, P.F.; Perez, J.L.; Watson, S.; Jones, L.C.; McGwin, G.; Ponce, B.A. The Rising Use of Total Hip Arthroplasty for Femoral Neck Fractures in the United States. HIP Int. 2020, 30, 107–113. [Google Scholar] [CrossRef] [PubMed]
  51. Wang, F.; Zhang, H.; Zhang, Z.; Ma, C.; Feng, X. Comparison of Bipolar Hemiarthroplasty and Total Hip Arthroplasty for Displaced Femoral Neck Fractures in the Healthy Elderly: A Meta-Analysis. BMC Musculoskelet. Disord. 2015, 16, 229. [Google Scholar] [CrossRef] [PubMed]
  52. Li, X.; Luo, J. Hemiarthroplasty Compared to Total Hip Arthroplasty for the Treatment of Femoral Neck Fractures: A Systematic Review and Meta-Analysis. J. Orthop. Surg. Res. 2021, 16, 172. [Google Scholar] [CrossRef] [PubMed]
  53. Wek, C.; Reichert, I.; Gee, M.; Foley, R.; Ahluwalia, R. Have Advances in Surgical Implants and Techniques in Hemiarthroplasty for Intracapsular Hip Fractures Improved Patient Outcomes Compared to THA? A Systematic Review and Meta-Analysis of the Evidence. The Surgeon 2022, 20, e344–e354. [Google Scholar] [CrossRef] [PubMed]
  54. Goru, P.; Haque, S.; Verma, G.G.; Mustafa, A.; Hamed, M.; Ismail, M.; Shah, S. Dislocation of Total Hip Replacement in Femoral Neck Fracture: Do Surgical Approach and Dual Mobility Implant Matter? Cureus 2022, 14, e21031. [Google Scholar] [CrossRef] [PubMed]
  55. Kamimura, T.; Kobayashi, Y.; Tamaki, S.; Koinuma, M. Impact of Prefracture Cognitive Impairment and Postoperative Delirium on Recovery after Hip Fracture Surgery. J. Am. Med. Dir. Assoc. 2024, 25, 104961. [Google Scholar] [CrossRef] [PubMed]
  56. Pieterse, A.J.; Luttikhold, T.B.; De Laat, K.; Bloem, B.R.; Van Engelen, B.G.; Munneke, M. Falls in Patients with Neuromuscular Disorders. J. Neurol. Sci. 2006, 251, 87–90. [Google Scholar] [CrossRef] [PubMed]
  57. Ryu, H.-G.; Roh, Y.J.; Oh, K.-J.; Hwang, J.-H.; Kim, Y.; Cho, H.-W.; Kim, S.-M. Dual Mobility Articulation Total Hip Arthroplasty for Displaced Neck Fracture in Elderly with Neuromuscular Disorder. Injury 2021, 52, 1480–1486. [Google Scholar] [CrossRef] [PubMed]
  58. Zhang, Y.; Yao, Z.; Shi, P.; Wang, C.; Liu, J.; Yang, Y.; Zhang, C. Morphological Risk Factors Associated with Dislocation after Bipolar Hemiarthroplasty of the Hip in Patients with Femoral Neck Fractures—A Nested Case-Control Study. J. Orthop. Surg. Res. 2019, 14, 395. [Google Scholar] [CrossRef] [PubMed]
  59. Zanna, L.; Innocenti, M.; Secci, G.; Cipolleschi, L.; Carulli, C.; Civinini, R. Acetabular Morphology Predicts the Risk of Dislocation Following Hemiarthroplasty for Femoral Neck Fractures in the Elderly. J. Arthroplast. 2023, 38, 1773–1778. [Google Scholar] [CrossRef] [PubMed]
  60. Lim, J.B.; Ang, C.L.; Pang, H.N. Acetabular Prosthetic Protrusio after Bipolar Hemi-Arthroplasty of the Hip: Case Report and Review of the Literature. J. Orthop. Case Rep. 2016, 6, 28–31. [Google Scholar] [CrossRef] [PubMed]
  61. Zi-Sheng, A.; You-Shui, G.; Zhi-Zhen, J.; Ting, Y.; Chang-Qing, Z. Hemiarthroplasty vs. Primary Total Hip Arthroplasty for Displaced Fractures of the Femoral Neck in the Elderly. J. Arthroplast. 2012, 27, 583–590. [Google Scholar] [CrossRef] [PubMed]
  62. Li, J.; Guo, Z.; Wang, T.; Xing, K.; Wang, W.; Liu, Y.; Xing, J.; Xiang, H.; Wang, J.; Chen, B.; et al. Treatment Trade-Offs and Choices for Femoral Fractures: A Systematic Review and Meta-Analysis. Orthop. Surg. 2025, 17, 1298–1313. [Google Scholar] [CrossRef] [PubMed]
Figure 1. Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) flowchart. DM: Dual Mobility Total Hip Arthroplasty, BH: Bipolar Hemiarthroplasty, THA: Total Hip Arthroplasty.
Figure 1. Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) flowchart. DM: Dual Mobility Total Hip Arthroplasty, BH: Bipolar Hemiarthroplasty, THA: Total Hip Arthroplasty.
Jcm 14 05076 g001
Figure 2. Forest plot for comparison of Operative Time [26,27,28,29,31,32,34,37,39,40,41].
Figure 2. Forest plot for comparison of Operative Time [26,27,28,29,31,32,34,37,39,40,41].
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Figure 3. Forest plot for comparison of Estimated Blood Loss [26,27,29,32,34,40,41].
Figure 3. Forest plot for comparison of Estimated Blood Loss [26,27,29,32,34,40,41].
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Figure 4. Forest plot for comparison of Postoperative Harris Hip Score [29,30,32,33,34,39,40,41].
Figure 4. Forest plot for comparison of Postoperative Harris Hip Score [29,30,32,33,34,39,40,41].
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Figure 5. Forest plot for comparison of Dislocation Rate [26,27,28,29,31,32,33,34,35,36,37,38,39,40,41].
Figure 5. Forest plot for comparison of Dislocation Rate [26,27,28,29,31,32,33,34,35,36,37,38,39,40,41].
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Figure 6. Forest plot for comparison of Reoperation Rate [26,27,28,31,32,33,35,38,39,41].
Figure 6. Forest plot for comparison of Reoperation Rate [26,27,28,31,32,33,35,38,39,41].
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Figure 7. Forest plot for comparison of Mortality Rate [26,27,28,29,30,31,32,33,34,36,38,39,41].
Figure 7. Forest plot for comparison of Mortality Rate [26,27,28,29,30,31,32,33,34,36,38,39,41].
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Table 1. Study design of the included studies and patients’ demographics.
Table 1. Study design of the included studies and patients’ demographics.
AuthorsYear, CountryStudy TypeTotal Number
of Patients
(BH/DM)
Time of SurgeryAge at Surgery * (Years)
(BH/DM)
Follow up * (Months)
(BH/DM)
Sex
(BH/DM)
(Men–Women)
Studied
Outcomes
Bensen et al [26].2014, DenmarkRCS3462007–201084.1/75.925.3/21.740–131/52–123BL, Disl, R & M
(171/175)
Ochi et al. [27]2017, JapanRCS532009–201580/75.428.2/15.84–16/7–26BL,
Disl, R & M
(20/33)
Boukebous et al. [28]2018, FranceRCS1992010–201583.3/77.825.8/24.228–73/28–70Disl, R & M
(101/98)
Kim et al. [29]2018, South KoreaRCS1682007–201672.9/73.122.1/21.727–57/26–58BL, Disl &
M, HHS
(84/84)
Fahad et al. [30]2019, PakistanRCS1042015–201771.1/69.320.6/10.931–46/13–14M, HHS
(77/27)
Iorio et al. [31]2019, ItalyRCT602015–201783/8212/1213–17/12–18Disl, R & M
(30/30)
Ukaj et al. [32]2019, KosovoRCT942008–201477.6/78.136/3632–15/23–24BL, Disl, R & M, HHS
(47/47)
Nonne et al. [33]2019, ItalyRCS1482013–201786.1/87.628.322–66/15–45Disl & R
(88/60)
Makeen et al. [34]2021, EgyptRCT332018–202071.1/70.42410–7/7–9BL, HHS
Disl
(17/16)
Bertault-Le Gourrierec et al. [35]2022, FranceRCS2652010–201385.4/78.56228–84/42–111Disl, R & M
(112/153)
Cnudde et al. [36]2022, SweedenRCS90332005–201483.3/77.9≥362941–5920/70–102Disl, R & M
(8861/172)
Rotini et al. [37]2022, ItalyRCS3022018–201987/84.8≥631–62/54–155Disl & M
(93/209)
Valcarenghi et al. [38]2022, BelgiumRCS2572015–201985/8117.6/18.126–113/21–97Disl, R & M
(139/118)
Pala et al. [39]2024, ItalyRCS1622020–202278/7410.3/14.520–62/19–61BL, HHS
Disl &R
(82/80)
Heshmat et al. [40]2024, EgyptRCT402018–202172.5/69≥249–11/5–15BL, HHS
Disl & M
(20/20)
Xiao et al. [41]2025, ChinaRCS1962017–202169.1/68.7≥3642–52/43–59BL, HHS
Disl, R & M
(94/102)
* Mean, BH: Bipolar Hip Hemiarthroplasty, DM: Dual Mobility Total Hip Arthroplasty, RCS: Retrospective Comparative Study, HHS: Harris Hip Score, RCT: Randomised Controlled Trial, BL: Blood Loss, Disl: Dislocation, R: Reoperation. M: Mortality rate.
Table 2. Comparative outcomes between BH and DM in the included studies.
Table 2. Comparative outcomes between BH and DM in the included studies.
AuthorsOutcomes
Estimated Blood Loss * (mL)Dislocation
Rate **
Reoperation Rate **Mortality Rate ***HHS **
BH–DMBH–DMBH–DMBH–DMBH–DM
Bensen et al. [26]310–42425/171–8/17532/171–16/17550/171–30/175N/A
Ochi et al. [27]148–4800/20–0/332/20–0/334/20–2/30N/A
Boukebous et al. [28]N/A10/101–3/989/101–7/9822/101–12/98N/A
Kim et al. [29]489–6343/84–2/84N/A6/84–7/8479.3–83.4
Fahad et al. [30]N/AN/AN/A4/77–0/2768.8–76.8
Iorio et al. [31]N/A5/30–0/301/30–0/305/30–4/30N/A
Ukaj et al. [32]159–1783/47–0/474/47–0/4712/47–7/4788.3–92.5
Nonne et al. [33]N/A5/88–0/604/88–1/60N/A81.7–79.8
Makeen et al. [34]365–5281/16–1/15N/AN/A70.4–77.9
Bertault-Le Gourrierec et al. [35]N/A7/112–3/15310/35–9/97102/112–69/152 aN/A
Cnudde et al. [36]N/A293/7876–4/149N/A36.4–27.9%N/A
Rotini et al. [37]N/A2/93–4/209N/A15/93–21/209 bN/A
Valcarenghi et al. [38]N/A12/139–2/11826/139–10/11825/139–19/118N/A
Pala et al. [39]N/A0/82–0/800/82–3/80N/A81–87.5
Heshmat et al. [40]700–4302/20–0/–N/A1/20–1/20 c88–92.5
Xiao et al. [41]257–2854/94–2/1021/92–0/1024/94–4/10285–89.5
* Mean. ** At the last follow-up. *** At 1 year post-operatively. a at five years follow-up, b at six months follow-up, c at two years follow-up. BH: Bipolar Hemiarthroplasty, DM: Dual Mobility Total Hip Arthroplasty, Hgb: Haemoglobin, HHS: Harris Hip Score, N/A: Not Available.
Table 3. Surgical characteristics of the included studies.
Table 3. Surgical characteristics of the included studies.
AuthorSurgical
Approach
(BH/DM)
Operative Time * (minutes)
(BH/DM)
Fixation Type **
(%)
(BH/DM)
Type of
Implants
(BH/DM)
Other Technical ConsiderationsCriteria for Allocation to Either BH, DM
Bensen et al. [26]PL68/74US: 94.4/94.6
UC: 98.3
Stems: Corail/Corail, ANCA-FIT™, Cups: SaturnePC and SER repair, Limited DM previous experience, MSPreexisting OA: (DM), SP, Time period:
(2007–8: BH, 2009–10:DM)
Ochi et al. [27]DAA89.4/108.3US: 100
UC: 100
Stems: Profemur TL, AccoladeTMZF, TriLock
Cups: Trident, MDM
Fluoroscopy use, additional cups screws in osteoporotic bone, MSTime period: (2009–13: BH, 2013–15: DM)
Boukebous et al. [28]PL85/102US: 22/ 55
UC: 70
Stems: Sem3 (CS), Louxor (UC), Cups: Galliléa (CC), Evora (UC)
MS
Time period: (2010–13: BHA, 2013–15: DM)
Kim et al. [29]PL64.2/77.3US: 100
UC: 100
Stems: Accolade TMZF
Cups: Trident PSL MDM
PC and SER repair, fluoroscopy use, SSTime period: (2007–13: BH
2013–16: DM)
Fahad et al. [30] DL, PLN/AUS: 100
UC: 100
Stems: porous coated
Cups: titanium alloy with HY coating
Cups stabilisation with two pegs and a screw, MSN/A
Iorio et al. [31] DL48/59US: 100
UC: 100
Stems: Excia/Pavi
Cups: Quattro
N/A-Randomisation
Ukaj et al. [32]PL57.8/63.7US: 34.4
UC: 100
Stems: Pavi
Cups: Quattro
PC repair, Cups stabilisation with six fins & four spikes, SS-Randomisation
Nonne et al. [33]PLN/AUS: 85.2
UC: 96.7
Stems: S-Taper, Korus
Cups: Dualis
N/AN/A
Makeen et al. [34]PL66/95US: N/A
UC: 100
Stems: Exception, CPT/Exception
Cups: Serf NOVAE Evolution
-PC and SER repair-Randomisation
Bertault-Le Gourrierec et al. [35]PLN/AUS: 25 /85
UC: 92
Stems: N/A/ Cups: Liberty ATF, Novae SERF, othersMSSP, Patient factors
Cnudde et al. [36]DL:65.3%, PL:34.7%/
DL:40.1%, PL:59.9%
N/AUS: 0
UC: N/A
N/AMS and institutionsInstitution dependent
Rotini et al. [37]PL66.3/78.6Both US & CS, (%N/A)
Both UC & CC, (%N/A)
Stems: CCA, MS-30, SL/PolarStem, Taperloc, Hype, Apta Fix, Exeter, ABG, Accolade, Apta
Cups: PolarCups, Avantage, Novae Stick, Trident, Novae
MS and institutionsSP, Patient factors
Valcarenghi et al. [38]PLN/AUS: most cases, (%N/A)
UC: 100
N/APC and SER repair, MSPreexisting OA: (DM-THA)
SP
Pala et al. [39]DA:4.9%, PL:3.6%,
AL: 91.5%/
DA: 27.5%, PL:12.5%, AL:60%
85/101US: 26.8
UC: 100
Stems: H-max, CL-trauma /Hype
Cups: NOVAE SunFit
MSPatient factors
Heshmat et al. [40]DL54.3/81.6US: 0
UC: 40
Stems: N/A
Cups: Avantage
MS-Randomisation
Xiao et al. [41]N/A76.8/86.4N/AN/AN/AN/A
* Mean, ** Results are given as percentages of uncemented implants; the rest are cemented, BH: Bipolar Hip Hemiarthroplasty, DM: Dual Mobility Total Hip Arthroplasty, US: Uncemented Stems, UC: Uncemented Cups, CS: Cemented Stems, CC: Cemented Cups, SER: Short External Rotators, OA: Osteoarthritis, SOC: Standard of Care, DA: Direct Anterior approach, DL: Direct Lateral approach, PL: Posterolateral approach, AL: Anterolateral approach, HY: hydroxyapatite, PC: posterior capsule, N/A: Not Available, MS: multiple surgeons, SS: Single surgeon, SP: Surgeon preference.
Table 4. Cognitive and neuromuscular status of patients in the included studies.
Table 4. Cognitive and neuromuscular status of patients in the included studies.
AuthorCognitive Impairment %
(BH/DM)
Neuromuscular Deficit %
(BH/DM)
Bensen et al. [26]N/AN/A
Ochi et al. [27]N/A10/24.2
Boukebous et al. [28]50/25N/A
Kim et al. [29]0 *0 *
Fahad et al. [30]N/AN/A
Iorio et al. [31]100 **0 **
Ukaj et al. [32]0 0
Nonne et al. [33]100 ***
Makeen et al. [34]N/AN/A
Bertault-Le Gourrierec et al. [35]27.25.8
Cnudde et al. [36]100 ***
Rotini et al. [37]N/AN/A
Valcarenghi et al. [38]32/40N/A
Pala et al. [39]0 * 0 *
Heshmat et al. [40]N/AN/A
Xiao et al. [41]0 * 0 *
* Patients with either cognitive impairment or a neuromuscular disorder were excluded from the study. ** Only patients with cognitive impairment but without a neuromuscular disorder were included in the study. *** Only patients with either cognitive impairment or a neuromuscular disorder were included in the study. BH: Bipolar Hip Hemiarthroplasty, DM: Dual Mobility Total Hip Arthroplasty, N/A: Not Available.
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MDPI and ACS Style

Grammatikopoulos, D.; Pegios, V.F.; Tsotsolis, S.; Kenanidis, E.; Tsiridis, E. Are There Benefits of Total Hip Arthroplasty with Dual-Mobility Cups Compared to Bipolar Hemiarthroplasty for Femoral Neck Fractures in the Geriatric Population? A Systematic Review and Meta-Analysis of Comparative Studies. J. Clin. Med. 2025, 14, 5076. https://doi.org/10.3390/jcm14145076

AMA Style

Grammatikopoulos D, Pegios VF, Tsotsolis S, Kenanidis E, Tsiridis E. Are There Benefits of Total Hip Arthroplasty with Dual-Mobility Cups Compared to Bipolar Hemiarthroplasty for Femoral Neck Fractures in the Geriatric Population? A Systematic Review and Meta-Analysis of Comparative Studies. Journal of Clinical Medicine. 2025; 14(14):5076. https://doi.org/10.3390/jcm14145076

Chicago/Turabian Style

Grammatikopoulos, Dimitrios, Vasileios F. Pegios, Stavros Tsotsolis, Eustathios Kenanidis, and Eleftherios Tsiridis. 2025. "Are There Benefits of Total Hip Arthroplasty with Dual-Mobility Cups Compared to Bipolar Hemiarthroplasty for Femoral Neck Fractures in the Geriatric Population? A Systematic Review and Meta-Analysis of Comparative Studies" Journal of Clinical Medicine 14, no. 14: 5076. https://doi.org/10.3390/jcm14145076

APA Style

Grammatikopoulos, D., Pegios, V. F., Tsotsolis, S., Kenanidis, E., & Tsiridis, E. (2025). Are There Benefits of Total Hip Arthroplasty with Dual-Mobility Cups Compared to Bipolar Hemiarthroplasty for Femoral Neck Fractures in the Geriatric Population? A Systematic Review and Meta-Analysis of Comparative Studies. Journal of Clinical Medicine, 14(14), 5076. https://doi.org/10.3390/jcm14145076

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