You are currently viewing a new version of our website. To view the old version click .

Vaccines, Volume 10, Issue 11

November 2022 - 206 articles

Cover Story: Current SARS-CoV-2 vaccines are administered systemically and result in poor immunogenicity at the mucosa, ultimately failing to prevent infection. We engineered B. subtilis spores to express SARS-CoV-2 antigens and used these to nasally boost a systemic prime consisting of either the rSpike protein or the AZD1222 vaccine. This heterologous systemic prime–mucosal boost strategy evoked mucosal IgA and is potentially protective, as shown in the hamster model of SARS-CoV-2 infection. Coupled with their ease of production, heat stability, and extraordinary resistance properties, spore vaccines, used mucosally, lend themselves to pandemic situations, facilitating a method with which to both augment systemic immunity as well as induce mucosal immunity, a prerequisite for complete protection. Such an approach is likely to have applications in other viral diseases. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (206)

  • Article
  • Open Access
6 Citations
2,447 Views
15 Pages

Evaluation of the Oral Microcirculation in Patients Undergoing Anti COVID-19 Vaccination: A Preliminary Study

  • Adriana Acquaro,
  • Giorgia Brusca,
  • Sofia Casella,
  • Enzo Maria Cumbo,
  • Antonio Della Valle,
  • Mohmed Isaqali Karobari,
  • Giuseppe Marino,
  • Anand Marya,
  • Pietro Messina and
  • Giuseppe Alessandro Scardina
  • + 3 authors

21 November 2022

Videocapillaroscopy allows the study of both the morphological and architectural structure of the microcirculation and its hemodynamic conditions; these parameters are directly involved in autoimmune and/or inflammatory pathologies. The purpose of th...

  • Article
  • Open Access
14 Citations
4,986 Views
14 Pages

Stakeholder Perspectives of Australia’s National HPV Vaccination Program

  • Caitlin Swift,
  • Aditi Dey,
  • Harunor Rashid,
  • Katrina Clark,
  • Ramesh Manocha,
  • Julia Brotherton and
  • Frank Beard

21 November 2022

Australia has been a world leader in human papillomavirus (HPV) vaccination and was the first country to implement a fully funded national HPV vaccination program, from 2007 for girls and 2013 for boys. In 2018 the program changed from a 4-valent to...

  • Article
  • Open Access
11 Citations
3,721 Views
19 Pages

Allelic Variants of HLA-C Upstream Region, PSORS1C3, MICA, TNFA and Genes Involved in Epidermal Homeostasis and Barrier Function Influence the Clinical Response to Anti-IL-12/IL-23 Treatment of Patients with Psoriasis

  • Martina Morelli,
  • Marco Galluzzo,
  • Claudia Scarponi,
  • Stefania Madonna,
  • Giovanni Luca Scaglione,
  • Giampiero Girolomoni,
  • Marina Talamonti,
  • Luca Bianchi and
  • Cristina Albanesi

21 November 2022

Several biologic therapies have been developed to treat moderate-to-severe psoriasis, with patients exhibiting different clinical benefits, possibly due to the heterogeneity of pathogenic processes underlying their conditions. Ustekinumab targets the...

  • Opinion
  • Open Access
1 Citations
2,710 Views
5 Pages

21 November 2022

The recurrence of the COVID-19 pandemic in 2022 has had a great impact on people’s mentality, although the government has controlled it through a series of effective measures. What is noteworthy is that the public opinion on vaccines has change...

  • Article
  • Open Access
4 Citations
4,455 Views
11 Pages

Freedom of Choice to Vaccinate and COVID-19 Vaccine Hesitancy in Italy

  • Mawulorm K. I. Denu,
  • Alberto Montrond,
  • Rachael Piltch-Loeb,
  • Marco Bonetti,
  • Veronica Toffolutti,
  • Marcia A. Testa and
  • Elena Savoia

21 November 2022

Despite the availability of effective vaccines that lower mortality and morbidity associated with COVID-19, many countries including Italy have adopted strict vaccination policies and mandates to increase the uptake of the COVID-19 vaccine. Such mand...

  • Case Report
  • Open Access
3 Citations
4,098 Views
7 Pages

A Case of Purpura Annularis Telangiectodes of Majocchi after Anti-SARS-CoV-2 Pfizer-BioNTech Vaccine: Is There an Association?

  • Francesca Ambrogio,
  • Carmelo Laface,
  • Giorgia Sbarra,
  • Raffaele Filotico,
  • Girolamo Ranieri,
  • Chiara Barlusconi,
  • Aurora De Marco,
  • Gerardo Cazzato,
  • Domenico Bonamonte and
  • Paolo Romita
  • + 1 author

21 November 2022

The advent of vaccines has drastically reduced the incidence, morbidity, and mortality related to COVID-19, and with the increase in the number of vaccinated subjects, there have been reports of some adverse events, including skin reactions. In this...

  • Article
  • Open Access
49 Citations
3,829 Views
8 Pages

Comparison of Biological, Pharmacological Characteristics, Indications, Contraindications and Adverse Effects of JYNNEOS and ACAM2000 Monkeypox Vaccines

  • Sultan Ayoub Meo,
  • Abeer A. Al-Masri,
  • David C. Klonoff,
  • Abdullah Nasser Alshahrani and
  • Thamir Al-khlaiwi

21 November 2022

Human monkeypox is an emerging viral zoonotic disease, that has caused highly distinctive, challenging and threatening problems worldwide. The US Food and Drug Administration (FDA) has given interim authorization for the JYNNEOS and ACAM2000 vaccines...

  • Article
  • Open Access
7 Citations
4,223 Views
12 Pages

Strengthening the Link between Vaccine Predispositions and Vaccine Advocacy through Certainty

  • Borja Paredes,
  • Miguel A. Martín Cárdaba,
  • Lorena Moreno,
  • Nerea Cano,
  • Pablo Briñol,
  • Ubaldo Cuesta and
  • Richard E. Petty

20 November 2022

Background. Instruments designed to assess individual differences in predispositions towards vaccination are useful in predicting vaccination-related outcomes. Despite their importance, there is relatively little evidence regarding the conditions und...

  • Viewpoint
  • Open Access
11 Citations
4,532 Views
9 Pages

20 November 2022

Genetic variants of vaccine poliovirus type 2, imported from an unknown source, were detected in waste waters in Jerusalem, London and New York in early 2022. Wild poliovirus type 2 was globally eradicated in 1999, but vaccine virus type 2 continued...

of 21

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Vaccines - ISSN 2076-393X