Benign Giant Cell Lesion of C1 Lateral Mass: A Case Report and Literature Review
AbstractPrimary osseous tumors of the spinal column account for approximately 1% of the total number of spinal tumors found in the pediatric patient population. The authors present a case of a C1 benign giant cell lesion that was incidentally found in a 15-year-old patient. A transoral biopsy was performed followed by treatment with denosumab, with definitive management in the form of transoral tumor resection with subsequent occiput-cervical three posterior instrumented fusion. The patient tolerated all of the procedures well, as there were no post-operative complications, discharged home neurologically intact and was eager to return to school when assessed during a follow-up visit in clinic. Osteolytic lesions affecting the cervical spine are rare in the pediatric population. It is of utmost importance to have sufficient background knowledge in order to formulate a differential diagnosis, as well as an understanding of principles underlying surgical techniques required to prevent occipital-cervical instability in this patient population. The information presented will guide surgical decision-making by identifying the patient population that would benefit from neurosurgical interventions to stabilize the atlantoaxial junction, in the context of rare osteolytic conditions affecting the cervical spine. View Full-Text
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Heinrich, C.; Gospodarev, V.; Kheradpour, A.; Zuppan, C.; Douglas, C.C.; Minasian, T. Benign Giant Cell Lesion of C1 Lateral Mass: A Case Report and Literature Review. Brain Sci. 2019, 9, 105.
Heinrich C, Gospodarev V, Kheradpour A, Zuppan C, Douglas CC, Minasian T. Benign Giant Cell Lesion of C1 Lateral Mass: A Case Report and Literature Review. Brain Sciences. 2019; 9(5):105.Chicago/Turabian Style
Heinrich, Christopher; Gospodarev, Vadim; Kheradpour, Albert; Zuppan, Craig; Douglas, Clifford C.; Minasian, Tanya. 2019. "Benign Giant Cell Lesion of C1 Lateral Mass: A Case Report and Literature Review." Brain Sci. 9, no. 5: 105.
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