Inertial Flow of Viscoelastic Second-Grade Fluid in a Ciliated Channel under a Magnetic Field and Darcy’s Resistance

: This paper proposes a mathematical analysis of the inertial ﬂow of an MHD second-grade non-Newtonian ﬂuid in a ciliated channel. The two-dimensional ﬂow is modelled under the effect of inertial forces, magnetic ﬁeld and Darcy’s resistance, which make the system of partial differential equations highly non-linear. To solve the complex system of partial differential equations, the Homotopy Perturbation Method (HPM) is preferred. The HPM solutions for the velocity proﬁle, stream function and pressure gradient are obtained using the software MATHEMATICA. The signiﬁcances of the Reynolds number (due to inertial forces), Hartmann number (due to magnetic ﬁeld), porosity parameter (due to Darcy’s resistance) and ﬂuid parameters (related to the second-grade ﬂuid) on the pressure gradient, stream function and velocity proﬁle are discussed in detail. The pertinent parameters show that the horizontal velocity decays in the presence of a magnetic ﬁeld, whereas it rises under the effect of inertial forces, Darcy’s resistance and ﬂuid viscosity in the centre of the channel. This research indicates that, for the ciliary ﬂow of a second-grade ﬂuid, a favourable pressure gradient (negative pressure gradient) in the horizontal direction increases when applying a magnetic ﬁeld, whereas it decreases due to the porous medium. This mathematical model can be helpful to observe ciliary activity under magnetic resonance imaging, when ciliary activity is abnormal.


Introduction
Cilia are small hair-like structures found in most microorganisms, human and animals. Cilia play a key role in the respiratory system, but also in the reproductive and digestive systems of humans and for the locomotion of small animals in biofluids. Motile cilia responsible for the transport of biofluids exhibit a rhythmic waving motion that forms metachronal waves. Metachronal waves produced by the motion of ciliary organs spread along out of phase in a distensible conduit. The key role of metachronal waves is to regulate the continuity of the flow. Ciliated surfaces can exhibit various beating patterns and generate multiple types of metachronal waves, of which, the two most frequent ones are symplectic and antiplectic metachronal waves, considered for the first time by Knight [1]. Later, few authors explored the motion of cilia forming symplectic wave patterns with numerous biotic fluids using analytical and numerical techniques, including Siddiqui et al. [2], who found an analytic solution for a Newtonian fluid flow through a ciliated channel, or Maiti and Pandey [3], who explored a viscous fluid flow through a ciliated tube. Periciliary dyskinesia disease is mainly due to defects in the airway cilia beating pattern and/or ciliary mortality. The main causes for that are related to the excessive mucus layer thickness and its excessive dynamic viscosity due to a default in the transmembrane transport of ions, inducing both a stagnation of mucus and inflammation.
The most common respiratory diseases related to cilia alterations are sinusitis and chronic bronchitis, asthma [4], infection and inflammation, bronchopneumonia and acute trachea bronchitis [5].
Since the viscous fluid plays a key role in the ciliary flow, different authors studied mucus flow by taking different non-Newtonian fluid models. For example, Liron and Rozenson [6] considered mucus (viscous fluid) as a linearized Oldroyd-B fluid. They represented the action of forces exerted by the cilia tip by impulsive forces. Mathematical equations were modelled and solved by the Fourier transform method. They confirmed that cilia penetration is necessary for an efficient transport. King et al. [7] studied the bio rheological effect of mucus due to ciliary motion and found that the reduction in the shear stress leads to an increase of mucus transport.
Smith et al. [8] presented a new mathematical model in which mucus is considered as a linear Maxwell fluid, and cilia are considered as an active porous medium. The periciliary layer (PCL) and mucus layer are separated by a thin layer. The system is solved by the Fourier series expansion method. The pressure gradient at the mucus-PCL interface and the cilia beating frequency are two key components for efficient mucus transport. Lee et al. [9] measured mucociliary transport by considering a Newtonian fluid for both PCL and mucus and investigated the factors affecting their transport and underlying diseases related to the respiratory tract, related to defects in the mucociliary clearance process. Results were obtained numerically and compared with those of the projection method. The main features affecting mucociliary transport are the number of cilia, the cilia beating frequency and the PCL depth. Sedaghat et al. [10] considered mucus as an Oldroyd-B fluid and demonstrated, using the lattice Boltzmann method, that the viscoelastic property of mucus has a significant impact on the deformation of the interface between the mucus and the periciliary layer. Recently, Chateau et al. [11] studied the transportation and mixing induced by ciliary beating through a combined Lattice Boltzmann/Immersed Boundary method in a two-fluid environment. Both mucus and PCL were assumed as Newtonian fluids. They highlighted the superiority of antiplectic metachronal waves over symplectic ones to transport mucus. This was later confirmed by Mann et al. [12], using the fractional Adomian decomposition method. These authors modelled the fractional Burgers fluid through a ciliated channel with the periciliary layer and mucus, also velocity profiles had obtained for both types of wave pattern and concluded that antiplectic waves are more efficient for the transportation of a viscous fluid. Most bionic fluids are viscoelastic in nature [13]. Viscoelasticity is besides the essential rheological property of bronchial mucus [14,15]. Therefore, it is of prime importance to consider the non-Newtonian behaviour of mucus when investigating mucociliary transport. For the first time, the viscoelastic second-grade fluid flow due to the ciliary motion [16,17] is considered here under the effect of a magnetic field and inertial forces.
Furthermore, the interest in magnetohydrodynamics flows (MHD) has grown because of their broad industrial and health applications [18][19][20][21]. Ally et al. [22] investigated the application of mucolytics (i.e., the process of reducing elasticity, rigidity and viscosity of mucus by breaking down the chemical bonds in mucus) to enhance particle retention under moderate magnetic fields. For this, they used the frog plate model to compare the two different mucolytics and found that N-acetylcysteine and dextran sulphate are effective for moderate and sufficiently large particle concentrations, respectively. Some other investigators considered the MHD flow of linear and nonlinear fluids due to ciliary motion. Manzoor et al. [23] studied the influence of magnetohydrodynamics (MHD) for a non-Newtonian Jeffrey fluid flow produced by ciliary motion in a porous medium. The results were obtained by a semi-analytical Adomian decomposition method. Bhatti et al. [24] considered the Casson fluid model to study the influence of MHD for solidliquid suspensions on the ciliary motion in a porous medium. For the same configuration, Elkhair et al. [25] modelled the problem without applying the longwave length and low Reynolds number approximation. A series solution by the Adomian Decomposition Method was obtained, and the results showed that the magnetic field and Darcy's resistance reduced the magnitude of the velocity field. Siddiqui et al. [26] studied the MHD viscous flow for a ciliated planar channel embedded in a porous medium and concluded that mucus congestion in the respiratory tract can be cleaned by drugs containing magnetic nanoparticles.
A magnetic field has been widely used together with artificial cilia in microfluidic devices for mixing applications. These cilia can also be used for cell transportation, antifouling surfaces, biochemical targets such as proteins and chemical agent sensing. Vilfan et al. [27] investigated fluid motion due to self-assembled artificial cilia using chains of super-paramagnetic beads. The use of a magnetic field to actuate beating cilia in a simple non-reciprocal beating manner caused a uniform motion above the cilia tips. Gauger et al. [28] developed a numerical model of fluid transport due to the motion of artificial cilia made by super-paramagnetic elastic filaments that are actuated by an applied magnetic field. A better control of artificial cilia was obtained by driving them externally, using either a magnetic or an electric field. Sajid et al. [29] studied the inertial flow by considering flagellated micro-organisms swimming in an MHD viscoelastic second-grade fluid. They demonstrated that propulsion in the presence of a magnetic field surges for low inertial forces and drops for higher ones.
Fluid flows through a porous medium have numerous real-world applications in nature, e.g., natural flows in porous medium can be observed under pathological conditions of gallstones when they drop into the bile tubes and close them incompletely or fully. Darcy's law has also been used to study the ciliary flow of a biofluid assuming the ciliated carpet as a porous medium. Saleem et al. [30] considered a compressible flow of Jeffrey fluid through a porous medium and concluded that the average velocity of a viscoelastic fluid flow increases in the presence of a magnetic field through the porous medium.
The flow of a second-grade fluid under the low Reynolds number approximation has been recently addressed by Hina et al. [31], who concluded that viscoelastic effects are responsible for a drastic change in the flow field. Shaheen et al. [32] analysed the magnetically actuated mucociliary pumping in a bronchial tube due to ciliary motion. They noticed that the ciliary beating frequency can be controlled by the application of a magnetic field. However, the MHD flow of a second-grade fluid induced by ciliary motion in a porous medium with inertial forces has not been studied yet. This is of particular interest for the diagnosis of respiratory diseases by magnetic resonance imaging [32]. Therefore, the present study addresses the role of a magnetic field and inertial forces on second-grade fluid flow through a porous medium surrounded by ciliated walls.
In the present work, the flow of a second-grade fluid due to metachoronal motion of cilia is investigated, and the influence of moderate Reynolds number, magnetic field and porous medium on the velocity, pressure and stream functions is studied in detail. The momentum equations include inertial effects, which were always ignored in former studies [31,33]. The presence of a magnetic field and inertial forces reduces the momentum equations into a system of fourth-order non-linear partial differential equations with moving boundary conditions. Obtaining the solution of the highly nonlinear partial differential equations with nonhomogeneous boundary conditions is very challenging for researchers. Therefore, one attempts to solve this system by the analytical technique HPM [33] together with the software Mathematica. The resulting expressions for the pressure gradient, stream function and velocity profile are portrayed, and the influences of the Hartmann number (magnetic field), Reynolds number (inertial force), porosity parameter (porous medium) and viscoelastic parameter (second-grade fluid) are discussed in detail. Antiplectic and symplectic metachronal wave patterns are observed, and the results show that the antiplectic wave pattern produces high speed compared with the symplectic wave pattern. To the best of the authors' knowledge, such a comprehensive analysis has never been proposed so far in the literature.

Geometrical Modelling and Governing Equations
Let us consider the ciliary flow of an incompressible second-grade fluid [31] in a symmetric conduit under a constant applied magnetic field, as illustrated in Figure 1a. Assume that an infinite number of continuously beating cilia are present along the inner walls of the conduit, causing symplectic or antiplectic metachronal waves, which move towards the positive or negative x-direction with a wave speed denoted by c. The cilia bed for the mucus flow is considered as a porous medium, as already suggested by Shaheen et al. [32]. In the present research, the envelope model approach [3] is applied to transport the second-grade fluid by ciliary motion.
To study the ciliary flow, the two-dimensional momentum and continuity equations are considered under the effect of a constant magnetic field and inertial forces. A single cilium is assumed to follow an elliptical path (Figure 1b), but collectively, cilia produce a metachronal wave in the (x,y) plane. The mathematical representation of the fluid near the cilia tip is written as follows: in which (X 0 ,a) is the reference position of the cilium tip, α is the eccentricity of the elliptical motion, 2L is the length of the vertical region covered by the mucus, ε is the cilium length, λ is the wavelength of the metachronal wave, t is time, and c is the speed of the metachronal waves.

Geometrical Modelling and Governing Equations
Let us consider the ciliary flow of an incompressible second-grade fluid [31] in a symmetric conduit under a constant applied magnetic field, as illustrated in Figure 1a. Assume that an infinite number of continuously beating cilia are present along the inner walls of the conduit, causing symplectic or antiplectic metachronal waves, which move towards the positive or negative x-direction with a wave speed denoted by c. The cilia bed for the mucus flow is considered as a porous medium, as already suggested by Shaheen et al. [32]. In the present research, the envelope model approach [3] is applied to transport the second-grade fluid by ciliary motion.
To study the ciliary flow, the two-dimensional momentum and continuity equations are considered under the effect of a constant magnetic field and inertial forces. A single cilium is assumed to follow an elliptical path (Figure 1b), but collectively, cilia produce a metachronal wave in the (x, y) plane. The mathematical representation of the fluid near the cilia tip is written as follows: in which ( ,a) is the reference position of the cilium tip, is the eccentricity of the elliptical motion, 2 is the length of the vertical region covered by the mucus, is the cilium length, λ is the wavelength of the metachronal wave, is time, and is the speed of the metachronal waves. The expressions for the fixed and wave frames are linked by the following relations: where (x, y) and (u, v) are the independent and dependent variables in the wave frame and X, Y and U, V are the independent and dependent variables in the fixed frame. Non-dimensional quantities are introduced by the following expression: where p is pressure, 2h is the mean width of the region occupied by the mucus, and the rest of the quantities are defined in the nomenclature. The conservative laws of mass and momentum for the second-grade fluid model [31][32][33] in a non-dimensional form are as follows: where A = 2 β 2 ∂v ∂x The relevant boundary conditions are: The stream function ψ is defined as: After eliminating the pressure gradient and using the assumption β < 1, i.e., the mean width of the mucus is less than the wavelength [31], the governing equations in terms of ψ take the following form: In the above expression, higher powers of β are ignored, as β < 1. In addition, if Re and β tend to zero, then the above expression can be reduced into the model flow of inertial free flow of a second-grade fluid due to ciliary flow, as shown by Hina et al. [31]. When λ 1 = 0, the present study turns to the study of an MHD Newtonian fluid flow through ciliated channel embedded in a porous medium at a moderate Reynolds number, as proposed by Elkhair et al. [25].

Volumetric Flow Rate and Boundary Conditions
The volumetric flow rate at a certain instant in a fixed frame is given by: Introducing Equation (3) in Equation (12), one obtains: From Equations (12), (13) and (3), one obtains: The time-averaged flow over a period T is defined as: With the help of Equations (14) and (15), we have: Now, with the aid of Equations (2), (3) and (16), the mean flowrate is: One can also define the dimensionless forms of the time-averaged flow Q and q as: or where: If one chooses ψ = 0 at y = 0, then ψ = q at y = h. The boundary conditions can be written as: where:

Methodology
To solve Equation (11) with the boundary conditions given by Equation (21), the Homotopy Perturbation Method (HPM) is used. The linear operator L and the nonlinear operator N are chosen in the following manner: One establishes a homotopy ψ[r, p 1 ] : Ω × [0, 1] → R , which satisfies: where w 0 is the initial guess, and p 1 [0, 1] is the embedding parameter. According to HPM, one defines the homotopy Equation as: The corresponding boundary conditions are: One decomposes the stream function ψ and the flux q in the following series: One chooses the initial guess: And, making use of Equations (28)- (30) in Equations (26) and (27) and the same powers of p 1 on both sides, one obtains the following equations: with the boundary conditions: ∂y 5 . (33) with the boundary conditions: The solution of Equation (31) under the boundary conditions of Equation (32) can be easily found after using the value of ψ 0 in Equation (33), and by solving the resulting equation under the boundary conditions of Equation (34) with the help of "Mathematica", one can obtains the solution in the following form: The series solution obtained by the HPM is convergent, as the coefficients of higherorder solution become very small. It is also noted that when λ 1 → 0 , then only a zero-order system gives a nontrivial solution, and the final result matches with the solution obtained by Elkhair et al. [25]. Now, the pressure gradient can be found from the following expression: Here, one more physical quantity of interest is the non-dimensional skin friction coefficient c f , which is defined at the half width of the channel at y = h: The dimensionless form of Equation (39) is: where: The mathematical expressions for velocity, pressure, stream function and skin friction coefficient are obtained by the software "MATHEMATICA". Table 1 shows the results of horizontal and vertical velocity for a second-grade and Newtonian fluid in the upper half of channel under the effect of inertial force, magnetic field and porous medium. The negative and positive values of the velocity profile show that ciliary flow is generated by the to-and-fro motion of cilia. Numerical results show that horizontal velocity is maximum at the centre of the channel, and vertical velocity shows increasing and decreasing effects, which generates the wavy movement. It is also observed that the horizontal flow of the Newtonian fluid is larger than that of the second-grade fluid because the second-grade fluid has high viscosity compared with the Newtonian fluid. Table 1. Comparison of velocity distribution for a second-grade fluid when Re = 0.1 and for a Newtonian fluid obtained from Reference [25] for fixed values of M = 1, In this section, the effects of the Hartmann number M, porosity parameter K, fluid parameter λ 1 and Reynolds number Re on the velocity field, pressure gradient and stream function are investigated by fixing the values as mentioned in [2,31]. Note that the fluid parameter λ 2 could be used instead of λ 1 , as the second-grade fluid model satisfies the thermodynamic condition λ 1 + λ 2 = 0. Thus, one will quantify the effect of λ 1 on the velocity profile, pressure distribution and stream function. The implementation of the HPM solution can be validated by looking at the graphs: the horizontal velocity component is high at the centre of the channel because the flow is along the direction of the metachronal waves, and the vertical velocity component exhibits a sinusoidal behaviour which is assumed in the boundary conditions. Figure 2a,d illustrate the effects of the operating parameters M, K, Re and λ 1 on the horizontal velocity component. Their effects on the ciliated flow are prominent in the middle of the channel and insignificant nearby the channel walls, which generates the parabolic behaviour of the flow due to the force caused by the tips of the cilia bed. Figure 2a shows that the Hartmann number M, which is the ratio of the electromagnetic to the viscous forces, weakens the horizontal velocity because the electromagnetic force is applied in the transverse direction of the flow. In the present study, the magnetic force is dominant over the viscous one, which helps to slow the ciliary flow and can be used to observe the activity of ciliary motion by resonance imaging for diagnostic purposes. Figure 2b shows that the porosity parameter K helps to assist the axial flow. The porosity parameter is the ratio of the pore volume to the bulk volume, which is generally less than one. It shows that if the bulk volume of dense cilia reduces and the pore volume grows, then a parallel flow rises near the middle of the channel, because the fluid has more space to flow through the pores. Figure 2c shows that the velocity profile in the horizontal direction increases with the increasing value of the second-grade fluid parameter λ 1 because of the presence of a magnetic field and the Reynolds number, which causes a reduction in fluid viscosity. Figure 2d displays that the Reynolds number supports the accelerating flow of the second-grade viscous fluid.

Results and Discussion
The behaviour of the vertical velocity component is displayed in Figure 3a Figure 4a,d illustrate that the horizontal pressure gradient along the flow exhibits a periodic behaviour. A favourable pressure gradient ( ∂p ∂x < 0) surges when the intensity of the magnetic field and/or the porosity increase. The cilia require more pressure to induce the fluid flow in the presence of a magnetic field applied in the transverse direction. On the contrary, the porous medium assists the fluid flow in the flow direction; therefore, the horizontal pressure gradient is a reducing function of the porosity parameter. Figure 4c,d show the dual behaviour of the horizontal pressure gradient by developing fluid viscosity λ 1 and inertial forces Re. The pressure gradient decays in the regions −1 < x < −0.5 and 0 < x < 0.5, while it rises in the regions −0.5 < x < 0 and 0.5 < x < 1 by increasing λ 1 and Re.
The behaviour of the vertical pressure gradient is presented in Figure 5a,d. It is symmetric about the centreline and behaves like a sinusoidal wave. The vertical pressure gradient is favourable (negative pressure gradient) in the region −0.5 < x < 0 and adverse (positive pressure gradient) in the region 0 < x < 0.5. Increasing the values of λ 1 and K leads to an increase of the pressure gradient amplitude, the Hartmann number M having an opposite influence. It is also observed that near the upper wall (y = 0.5), the pressure gradient amplitude increases in the flow direction due to the recovery and effective stroke of the cilia beating. (c) (d)       The streamlines are displayed in Figures 6-9 for different values of the Hartmann number M, porosity parameter K, fluid parameter λ 1 and Reynolds number Re. Figure 6a-c demonstrate that increasing the Hartmann number M leads to more resistance for the inertial flow; therefore, the bolus size reduces. It can be observed from Figure 7a-c that the bolus size rises with increased values of the porosity parameter K, as it allows the fluid to flow more easily through the pores. Figure 8a-c indicate that, by increasing the fluid parameter λ 1 , the size of the trapped bolus rises. As shown in Figure 9a-c, the bolus size and the number of streamlines become larger when the inertial forces are dominant over the viscous forces (increasing the Re number).    Comparisons of the velocity profiles for both symplectic and antiplectic metachronal waves are shown in Figures 10 a,b. It is noteworthy that the same behaviour is observed for both symplectic and antiplectic waves: if the length of the cilium increases, the amplitude of the velocity profiles becomes larger. However, the most important conclusion is that the horizontal velocity component (Figure 10a) is much higher for the antiplectic waves. Therefore, antiplectic waves are more efficient to transport a second-grade fluid in the presence of a magnetic field than symplectic waves, which confirms former results in the literature for a Newtonian fluid obtained by more complex numerical simulations [13]. The larger magnitude of the vertical velocity profiles for the antiplectic waves (Figure 10b) is in line with the blowing-suction mechanism highlighted by Chateau et al. [34] using a lattice Boltzmann solver. The authors showed that this mechanism is responsible for the enhanced transport capability of antiplectic waves over symplectic ones. . Comparisons of the velocity profiles for both symplectic and antiplectic metachronal waves are shown in Figure 10a,b. It is noteworthy that the same behaviour is observed for both symplectic and antiplectic waves: if the length of the cilium increases, the amplitude of the velocity profiles becomes larger. However, the most important conclusion is that the horizontal velocity component (Figure 10a) is much higher for the antiplectic waves. Therefore, antiplectic waves are more efficient to transport a second-grade fluid in the presence of a magnetic field than symplectic waves, which confirms former results in the literature for a Newtonian fluid obtained by more complex numerical simulations [13]. The larger magnitude of the vertical velocity profiles for the antiplectic waves (Figure 10b) is in line with the blowing-suction mechanism highlighted by Chateau et al. [34] using a lattice Boltzmann solver. The authors showed that this mechanism is responsible for the enhanced transport capability of antiplectic waves over symplectic ones.     Figure 11 displays the skin friction coefficient as a function of the second-grade parameter λ 1 for different values of the cilia length ε. It shows the linear relation between the skin friction coefficient, which is a measure of the fluid resistance on the wall, and λ 1 through the straight line when ε = 0.1, which becomes nonlinear when ε = 0.2 and 0.3.
Numerical results of velocity, pressure, stream function and shear stress are calculated by the Homotopy perturbation method (HPM) and shown through graphs. The distributions of velocity, pressure and shear stress are smooth. They also satisfy the boundary conditions defined for the velocity profile with decreasing coefficients of higher-order solutions, which guarantees that the series solution obtained with the HPM converges in the region −h < y < h and provides the best results of the present study. Numerical results of velocity, pressure, stream function and shear stress are calculated by the Homotopy perturbation method (HPM) and shown through graphs. The distributions of velocity, pressure and shear stress are smooth. They also satisfy the boundary conditions defined for the velocity profile with decreasing coefficients of higher-order solutions, which guarantees that the series solution obtained with the HPM converges in the region -h<y<h and provides the best results of the present study.

Conclusions
In this study, we investigated, for the first time, the effect of inertial forces (Re ≠ 0) on the magneto-hydrodynamic flow of a second-grade fluid through a ciliated conduit. The nonlinear system of partial differential equations was solved by the Homotopy Perturbation Method and the software Mathematica. The combined influences of the Reynolds number , Hartmann number , fluid parameter λ and porosity parameter on the velocity profiles, pressure gradient and stream function were quantified and discussed in detail. The main results gained from this analysis can be summarized as follows: The The results are useful to detect the frequency and motion of motile cilia under diseased conditions such as cystic fibrosis or bronchopneumonia. The application of a

Conclusions
In this study, we investigated, for the first time, the effect of inertial forces (Re = 0) on the magneto-hydrodynamic flow of a second-grade fluid through a ciliated conduit. The nonlinear system of partial differential equations was solved by the Homotopy Perturbation Method and the software Mathematica. The combined influences of the Reynolds number Re, Hartmann number M, fluid parameter λ 1 and porosity parameter K on the velocity profiles, pressure gradient and stream function were quantified and discussed in detail. The main results gained from this analysis can be summarized as follows: The horizontal velocity component decreases with increasing values of the Hartmann number M in the centre of the channel. On the contrary, it increases with increasing values of the Reynolds number Re, the porosity parameter K, and the fluid parameter λ 1 . The vertical velocity component vanishes in the centre of channel and behaves like a sinusoidal wave.
A favourable pressure gradient in the axial direction uniformly increases with the Hartmann number M and decreases with the porosity parameter K. It shows a dual behaviour for the fluid parameter λ 1 and the Reynolds number Re, whereas a favourable pressure gradient in the vertical direction is symmetric around the channel centre. It decreases for large values of the Hartmann number M, while it increases for larger values of the fluid parameter λ 1 and the Reynolds number Re.
The size of the trapped bolus reduces by increasing the Hartmann number M and expands by increasing the porosity parameter K and the fluid parameter λ 1 . However, both the size and the number of trapped boluses of a second-grade fluid in a ciliated channel increase by increasing the Reynolds number.
The skin friction coefficient (or shear stress) of the second-grade fluid exhibits a linear relation for ε = 0.1, whereas this relation becomes nonlinear for increasing values of the cilia length.
The results are useful to detect the frequency and motion of motile cilia under diseased conditions such as cystic fibrosis or bronchopneumonia. The application of a magnetic field for magnetic resonance imaging can detect a viscous fluid flow induced by ciliary motion. For future perspectives, the study will be extended to consider the influence of the temperature and surrounding environment on fluid transport.