Rodents as Hosts of Pathogens and Related Zoonotic Disease Risk
1
Aix-Marseille University, IRD, AP-HM, MEPHI, 13005 Marseille, France
2
IHU-Méditerranée Infection, 13005 Marseille, France
3
CBGP, IRD, CIRAD, INRA, Montpellier SupAgro, University Montpellier, 34980 Montpellier, France
4
Aix Marseille University, IRD, AP-HM, SSA, VITROME, 13005 Marseille, France
*
Author to whom correspondence should be addressed.
Pathogens 2020, 9(3), 202; https://doi.org/10.3390/pathogens9030202
Received: 10 February 2020
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Revised: 6 March 2020
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Accepted: 8 March 2020
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Published: 10 March 2020
Rodents are known to be reservoir hosts for at least 60 zoonotic diseases and are known to play an important role in their transmission and spread in different ways. We sampled different rodent communities within and around human settlements in Northern Senegal, an area subjected to major environmental transformations associated with global changes. Herein, we conducted an epidemiological study on their bacterial communities. One hundred and seventy-one (171) invasive and native rodents were captured, 50 from outdoor trapping sites and 121 rodents from indoor habitats, consisting of five species. The DNA of thirteen pathogens was successfully screened on the rodents’ spleens. We found: 2.3% of spleens positive to Piroplasmida and amplified one which gave a potentially new species Candidatus “Theileria senegalensis”; 9.35% of Bartonella spp. and amplified 10, giving three genotypes; 3.5% of filariasis species; 18.12% of Anaplasmataceae species and amplified only 5, giving a new potential species Candidatus “Ehrlichia senegalensis”; 2.33% of Hepatozoon spp.; 3.5% of Kinetoplastidae spp.; and 15.2% of Borrelia spp. and amplified 8 belonging all to Borrelia crocidurae. Some of the species of pathogens carried by the rodents of our studied area may be unknown because most of those we have identified are new species. In one bacterial taxon, Anaplasma, a positive correlation between host body mass and infection was found. Overall, male and invasive rodents appeared less infected than female and native ones, respectively.
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Keywords:
pathogens host; zoonotic disease; rodents; Bartonella; Borrelia crocidurae; Anaplasmataceae; Piroplasmida; Hepatozoon
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MDPI and ACS Style
Dahmana, H.; Granjon, L.; Diagne, C.; Davoust, B.; Fenollar, F.; Mediannikov, O. Rodents as Hosts of Pathogens and Related Zoonotic Disease Risk. Pathogens 2020, 9, 202. https://doi.org/10.3390/pathogens9030202
AMA Style
Dahmana H, Granjon L, Diagne C, Davoust B, Fenollar F, Mediannikov O. Rodents as Hosts of Pathogens and Related Zoonotic Disease Risk. Pathogens. 2020; 9(3):202. https://doi.org/10.3390/pathogens9030202
Chicago/Turabian StyleDahmana, Handi, Laurent Granjon, Christophe Diagne, Bernard Davoust, Florence Fenollar, and Oleg Mediannikov. 2020. "Rodents as Hosts of Pathogens and Related Zoonotic Disease Risk" Pathogens 9, no. 3: 202. https://doi.org/10.3390/pathogens9030202
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