Electrochemical Behavior of Biodegradable FeMnSi–MgCa Alloy

: Nowadays, alongside metallic biomaterials, there is increasing interest in using degradable metals in an appreciable number of medical applications. There are new kinds of metallic biomaterials for medical applications and many new ﬁndings have been reported over the past few years. Iron-based materials are a solution for biodegradable applications based on their mechanical and chemical properties. In order to control the corrosion rate of the Fe10Mn6Si alloy, we proposed the use of two additional elements, Ca and Mg, as corrosion promoters. The new material was obtained in an air-controlled atmosphere furnace after ﬁve melting operations. The material was in vitro analyzed from a corrosion resistance point of view. The experiments were realized by immersion (7, 14, and 30 days) in simulated body ﬂuid (SBF) solution at 37 ◦ C and a constant pH, and by electrochemical tests (electrochemical impedance spectroscopy (EIS), linear polarization (LP), cyclic polarization (CP)). Material surfaces before and after corrosion tests were analyzed through scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), and X-ray diffraction (XRD) techniques. A discussion on the degradation rate of the material was realized from a comparison of the results. The results presented good composition homogeneity after the re-melting stages, with low percentages of Ca and Mg in the material, but with an adequate spread in the alloy.


Introduction
The accelerated development in the last few years of medical techniques of intervention in treating disorders in reparatory surgery or for implants has led to the necessary increase of materials with a role in replacing live tissues or in sustaining the healing processes of these lesions. Generally speaking, these materials are called biomaterials. Biomaterials are synthetic materials used to replace part of a live tissue or to function in deep connection with a live tissue. In a classic manner, the implants are permanent and have to achieve two qualities: to be inert (deprived of reactivity concerning other chemical elements or the environment of implantation) and to be resistant to corrosion [1]. Clinical studies realized have demonstrated that in the case of some illnesses or traumas, it is necessary to have just one temporary support for healing, support that can be assured only by implantable Using high-purity metallic elements Fe (Armco 99.99%), Mn (99.98%), Si (99.9%), Mg (99%), and master alloys like SiCa (60-40% wt), MgCa (85-15% wt), we obtained a new metallic material FeMnSi-MgCa. The obtaining process consists of two stages: first, melting the Fe, Mn, and Si elements in an electric arc furnace (RAV MRF ABJ_900, Allenstown, NY, USA), and second, the addition of Mg and Ca elements using a vacuum induction furnace (UltraCast, Ronkonkoma, NY, USA) in a ceramic crucible. Calculations, taking in account the loss at high temperature, were made to obtain Fe10Mn6Si and additions of Mg and Ca within 1 wt%. The melting points of calcium (842 • C) and magnesium (650 • C) are very low in comparison to that of iron (1538 • C) and manganese (1246 • C). Due to the major difference between melting points, problems appear in achieving a homogenous solid solution of the nominal composition. After finishing the process of melting, the caster is removed from the furnace and the material cooled to room temperature. To obtain the homogenization, four re-meltings were performed, followed by the annealing of homogenization in a fluid bed (in sand) at 1050 • C for 300 min, the cooling being made simultaneously with the sand in which it was heated. This heat treatment plays an important role in reducing the heating fragility during the hot deformation process [11].
Immersion tests were realized in a temperature-controlled enclosure box (37 • C) for three similar samples in a re-circulated simulated body fluid solution with the chemical composition (presented in Table 1) and with a daily control of pH (approximately 7.5) [12]. The heating system of the experimental samples was provided with the possibility of turning at 180 • , and the operation was realized daily to expose the whole metallic surface to the SBF solution. For immersion, the samples were abraded (with abrasion papers of SiC up to 2000 grit) and the surface was cleaned in an ultrasound bath (30 min) in industrial alcohol. The samples were immersed for 7, 14, and 30 days. Additionally, the samples were weighed before and after the immersion with a micro-analytical balance scale (Premier −4 decimals). The products of corrosion unlinked to the biodegradable metallic materials based on Fe could be removed through the immersion in a solution (20 g of Sb 2 O 3 and 50 g of tin chloride were dissolved in 1000 mL of hydrochloric acid and sonication for 30 min [2,13]).
Electrochemical measurements were performed using a Dynamic Electrochemical System VoltaLab 40 (PGZ301) (Radiometer Analytical SAS, Lyon, France) on three samples for the experimental material in SBF at 37 ± 1 • C. The experimental set-up was made in a three-electrode cell connected with potentiostat equipment with the alloy sample (ground up to 2000 grit) with a rotating working electrode (50 rpm), a saturated calomel electrode (SCE) as the reference electrode, and a platinum wire as the counter electrode. The tests were repeated three times to achieve proper repeatability of the results.
Working cylinder electrodes were mounted in a Teflon support to enable the connection to the rotating electrode of electrochemical system. A 0.25-0.30 cm 2 cross area of the working electrode was used.
The acquisition and processing of the electrochemical data were achieved with the VoltaMaster 4 software (Radiometer Analytical, Lyon, France). The EIS data purchased with the VoltaMaster software were processed with ZSimpWin software (Princenton Applied Research, Farnborough, Hampshire, UK,) where the electrochemical spectra were interpreted by the least square method developed by Boukamp. For this purpose, the VoltaMaster data were converted to Z date with the EIS file converter (Radiometer Analytical S.A. Lyon, France).
The chemical composition details were obtained using energy-dispersive X-ray spectroscopy (EDX) Esprit software PB-ZAF with automatic and element list analyze modes detector from Bruker connected to scanning electron microscope (SEM) equipment-VegaTescan LMH II (30 kV, SE detector, high vacuum). Standard deviations were provided for all chemical determinations. The material surface was analyzed through X-ray diffraction (XRD) analysis using X'Pert equipment (20:20-90).

Results and Discussion
The experimental results presented preliminary information on the degradation rate of the new alloy. Through microscopy, the state of the surface before and after the tests of corrosion resistance was highlighted through immersion and linear and cyclic potentiometry. Through chemical analysis, the chemical compounds formed on the surface were determined and were followed by the chemical evolution of the alloy at the interface with the biological solution/electrolyte solution.

Surface Characterization
The surface state of the alloy FeMnSi-MgCa is presented in Figure 1, for the initial state and after immersion in SBF (at 37 • C) for 7, 14, or 30 days. The 2D and 3D images present corrosion (a corrosion pitting type quite agglomerated with the unification of the holes in most cases) with different aspects depending of the immersion period. The sizes of the pitting "holes" were of a micrometer scale for diameter/length/width and depth.
The surface of the sample maintained for 14 days presented the biggest tracks of corrosion and the presence of compounds with good stability on the material.
Immediately after immersion in the experimental solution, the alloy was oxidized to metal ions following reactions (1)-(4). The compounds formed on the surface after immersion were based on the alloy main elements, especially oxides. Anodic reactions were based on the component elements of the alloy.
The electrons from the anodic reaction were consumed by a corresponding cathodic reaction and the reduction of oxygen dissolved in water (reaction (5)).
Product formation on the material surface are based on reactions (6)-(10): Mn 2+ + 2H 2 O ↔ MnO 2 + 4H + + 2e − The corrosion by the oxidation surface layer of iron alloys is usually based on FeO·nH 2 O, Fe 3 O 4 ·nH 2 O and Fe 2 O 3 ·nH 2 O [14]. The XRD analysis detected magnetite Fe 3 O 4 and SiO 2 weak peaks alongside the peaks of the main elements.
The presence of the reaction compounds from the interaction between the metallic material and the immersion solution (SBF) was observed as well as in the case of the sample maintained in liquid for 30 days. In this interval, many interactions of the metallic material took place with the solution and different compounds were formed on the surface. In the case of the immersion for seven days, a deep corrosion of the surface (microns order) was observed. 3D images of the surface showed the presence of compounds with small sizes. This resulted from the reaction compounds on the surface growing and agglomerating during the immersion period. After a seven-day immersion period, an area affected by corrosion was observed at a proportion of 50%, and this surface grew gradually for 14 and 30 days, where the whole surface was corroded or covered the reaction compounds.

Surface Chemical Characterization
The experimental material surface was analyzed using the EDX technique to observe the evolution of the chemical element percentages after the immersion periods. The initial composition of the alloy is Fe 83.17, Mn 10.9, Si 5.44, Mg 0.6, Ca 0.20.
Chemical determinations were made before and after a sonication cleaning treatment. In Figure 2, the distributions of the elements Fe, Mn, Si, Mg, Ca characteristic of the immersed alloy and the distributions of the elements Na, Cl, O, and C that were identified through qualitative EDX analysis of the surface are presented. Daeho et al. [15] suggested that the phase precipitated along the grain boundaries was Mg 2 Ca after studying the microstructures of a binary Mg-Ca alloy. In our case, we also expected to have precipitates in the microstructure. For the sample immersed for seven days, traces of oxides on the surface, especially on the left side of the analyzed surface, were observed on the surface (Figure 2a), as was the presence of chlorine and sodium on the surface under the form of zonal compounds. From the pitting corroded areas, we observed a decrease of the signal for the elements Fe, Ca, and Mg. For the sample immersed for 14 days, we also observed an area of the alloy affected by corrosion, a zonal distribution of the compounds based on chlorine that coincided in some areas with those of sodium, possibly due to the formation of salts on the surface of the metallic material. In the last case, the sample immersed for 30 days, a corroded and oxidized surface could be seen with a larger number of chlorine compounds that appeared in the form of unstable, chemical formations on the surface of the alloy. On the surface of the sample immersed for 30 days, the appearance of the compound silica (SiO 2 ) was identified and further confirmed through XRD analysis. In the case of the sample immersed for 30 days, most of the corroded surface was covered by compounds resulting from the interaction with SBF solution. These compounds appeared as a result of the oxidation of the base elements of the alloy or after the deposition of compounds from the solution on the surface. To determine the stability of the compounds that appeared on the surface of the metallic material in the immersion period (with a very important role in the determination of the degradation characteristics of the alloy), the samples underwent a cleaning procedure. The chemical compositions of the surfaces after the cleaning stage with ultrasonication are presented in Table 2 (mass percentages and atomic percentages of the elements identified on the surface as well as the typical error of the EDX detector for each chemical element).
From Figure 3, in the case of the immersed sample for seven days, we observed the formation on the surface of Fe, Mn, and Si oxides as well as the appearance on the surface of salts that confirmed the analysis through the distribution of the elements presented previously.
After the ultrasonic cleaning (USC) stage (all the results are characterized by the following standard deviations: Fe: ±1.1; Mn: ±0.22; Si: ±0.3; Mg: ±0.1; Ca: ±0.05), we observed the separation of large quantities of silica oxides and some Fe and Mn oxides. We also observed a total removal of the salts from the surface following the cleaning stage. The alloying elements Mg and Ca did not appear any further, or were in very small quantities (0.05 wt% Ca) after cleaning the surface. This confirmed the role of these elements in increasing the degradation rate of the experimental alloy as well as in the smoothing of corrosion on the entire surface. After 14 days of immersion, we identified smaller amounts of oxides on the surface in comparison with the results on the immersed sample for seven days, affirming the validation for all of the Fe, Mn or Si oxides.
The percentages of Mn and Si after the cleaning stage were close to the initial values, a fact that signified an almost total transfer of the oxides of these elements in the immersion solution. Furthermore, after 14 days of immersion in SBF, Na salts and carbon-based compounds appeared on the surface (possible carbonates of MgCO 3 or CaCO 3 [2], that passed into the solution after the ultrasonic cleaning stage). There was also the possibility of the formation of some calcium carbonates from the experimental alloy that were not removed through the cleaning stage, a fact that explains the high percentage of mass of Ca and the presence of C on the surface after the cleaning operation.
After 30 days of immersion, the surface presented the lowest amount of oxides, mainly based on Fe and Si, and a larger amount of salts in comparison with the surfaces of the samples immersed for seven and 14 days. After cleaning, there were no more salts or carbon-based compounds. This confirmed the presence of a higher quantity of Si (observed in the distribution from Figure 2c), a fact that can be explained through the kinetics of the formation of Si oxides and also through the passing rates of Fe, Mn, and Si of these compounds in solution. After this immersion period, there was the first case where on the surface, after ultrasonic cleaning, also appeared the elements of Mg and Ca, pertaining mostly to the experimental alloy.   Analyzing the XRD graph of the experimental alloy, there were no characteristic peaks of pure Ca or Mg in the X-ray diffraction pattern (Figure 4). One reason for this could be that the weight percent of Ca or Mg considered in this study was lower than 1 wt%, which could influence below the detection limit of standard X-ray diffraction units. The shift in the peak position, in comparison with the literature [14], is indicated in the lattice parameter, reflecting the incorporation of these two elements into the Fe-Mn lattice as also presumed from the EDX results. Table 2 presents the main characteristics of the experimental samples used in the immersion test (length, width, and height of the samples) as well as the values of their weights before and after the periods of immersion and after cleaning the surfaces through sonication. The total area was calculated by taking into account all six areas exposed to the SBF solution. In the case of the immersion test for the calculus of corrosion rate (CR), some parameters are necessary (the mass of the samples before and after immersion, the surfaces of the samples, or the density of the experimental material). During the test, we determined both the loss of weight and the quantity of metallic ions freed in the solution (this solution will be approached in a future article). The corrosion rate of the biodegradable metallic materials can be calculated using Equation (11) [2]: where CR refers to the corrosion rate; W is the loss of mass calculated of the sample from biodegradable metallic material; A is the surface exposed at corrosion; t is the time of immersion; and ρ is the standard density of the alloy (in this case, the alloy had an experimental value of 6.122 g/cm 3 ). Using the data from  Applying Equation (1) to the experimental data obtained after sonication cleaning of the surface (Table 2), we determined the corrosion rate of the alloys that attended to the removal of the non-adherent compounds on the material surface. The values obtained were as follows: after seven days of immersion it was 768.294 µm/year; after 14 days of immersion it was 767.800 µm/year; and it was 308.99 µm/year after 30 days of immersion. The average rate of degradation was 615.028 µm/year.

Surface Electrochemical Characterization
Potentiodynamic polarization and the impedance measurements were the methods used to determine the corrosion rate of the biodegradable metallic materials. The density of the corrosion current i corr can be estimated from the analysis of the linear curve (Tafel) and can also be determined from the polarization resistance obtained from the impedance measurements using the Stern-Geary equation [16]. The corrosion rate can be calculated with Equation (12): where C R refers to the degradation rate, k 1 = 3.27 × 10 −3 mm·g·µA −1 ·cm −1 ·y −1 r ; i corr is the density of the corrosion current; ρ is the density of the metallic material (in this case the alloy has the experimental value of 6.122 g/cm 3 ); and W and n refer to the atomic mass of the main element Fe and its valence, respectively. Figure 5a shows representative Tafel curves obtained from the potentiodynamic linear polarization of the experimental alloy measured in SBF solution.
Upon anodic polarization, the Fe-Mn-Si + (MgCa) alloy shows, similar to Fe-1C, an active dissolution behavior, whereby in the low polarization regime up to about −0.3 V, the slope of the curves is steeper than that in the Fe-1C [17] curve, revealing higher dissolution rates. Consequently, the mass-transport controlled dissolution reflected by the current plateau is reached much earlier.
The effect of adding Ca and Mg was assessed by the potentiodynamic polarization test where the results showed an increased corrosion current density related to the amount of Ca and Mg present in the solid solution [18,19]. The corrosion current density (j corr ) is representative of the degradation degree of the alloy. It is evident from Figure 6 and Table 3 that, first, there was a decrease of corrosion current density after seven days which was associated with the formation of a thin oxide layer on the metallic surface, followed by a high increase of the current after 14 and 30 days. In comparison with FeMnSi alloy behavior, we had a j corr value approximately 12 times larger (695/59 µA/cm 2 ) [19]. Part of the difference could be attributed to the addition of small quantities of Mg and Ca. The lower values of the anode Tafel slope indicated that anodic oxidation was active while the higher values of the cathode Tafel slope indicated that the reduction processes (either hydrogen: 2H + + 2e − → H 2 or water: H 2 O + 2e − → H 2 + 2HO − or other ionic species in the solution) were controlled by' concentration and controlled the global corrosion process. Large differences between the cathode slopes could be attributed to the complexity of the reduction processes as well as the formation of the films on the surface of the alloy maintained in solution.
The electrochemical corrosion test performed in the SBF solution revealed medium-size grains [19,20] and a surface preferentially corroded based on the grain plate's orientation (Figure 5c). Small areas were covered with oxides and salts (Figure 5d) that formed a new layer of corrosion on top of the alloy's surface.
In quantitative terms, the corrosion potentials for the four samples were negative and quite large, ranging between −727 and −667.9 mV/ESC, placing this alloy in the category of being easily corrodible in SBF. The open circuit potential was greater than the potential for corrosion in all cases. This could be explained by the fact that while OCP is measured at a zero corrosion rate (at metal-solution equilibrium), Ecor (corrosion potential) is measured under dynamic conditions; by continuously altering the alloy potential, the surface reaction is more or less away from equilibrium. The higher the scanning rate of the potential, the more the reaction was farther away from the equilibrium and the Ecor deviated more from the OCP value [21]. Qualitatively, the thermodynamic tendency of corrosion of the alloy was greater when the surface of the alloy was freshly polished and decreased when the alloy remained in longer contact with the corrosion medium. From the point of view of the corrosion rate, it was observed that maintaining a relatively reduced time (seven days) in the solution led to passivation of the alloy; the corrosion rate dropped approximately 12 times. This may be due to the fact that by contacting the alloy with the solution, a slow corrosion process takes place, forming a compact (black) coating that protects the surface and leads to increased polarization resistances (Rp) and to the reduction of the cathodic current, which is controlled by diffusion (beta cathodic (bc) << beta anodic (ba)). Instead, maintaining a longer time (14 days) of the alloy in the solution led to much higher corrosion rates, even in the case of the newly mechanically polished surface. This may be due to the fact that with the increase in the thickness of the product layer, there are crevices through which the corrosion medium penetrates into the alloy.
The cyclic polarization curves for the FeMnSi-MgCa sample in SBF, recorded in the four cases (maintained 0 days, 7, 14, and 30 days in solution), are presented in Figure 5b. All curves were typical of generalized corrosion; the cathode branch perfectly overlapped the anodic branch. All curves were linear over the entire range of potential used; the current density, and as a result the corrosion rate, was increased directly to the overvoltage applied to the electrode.
The corrosion current density values are particularly high, suggesting advanced alloy corrosion in the SBF solution. In this case the smallest corrosion is encountered in the case of the alloy immersed for 7 days in the solution and the highest for the alloy maintained for 14 days in the solution. It can be observed that the corrosion process starts from potential (−0.5 V) and increases significantly with over potential.
Current densities increase appreciably at high over potentials; for example, for the 2000 mV/ESC electrode potential, the current density is approximately 300 times the density of the instantaneous current (at corrosion potential) for the surface with 0 days and for the surface maintained for 7 days in the SBF, but the increase is higher for alloy maintained for 14 days in SBF. This causes a pronounced corrosion of the alloys in a short period of time (a complete cycle takes about 8.5 min). The evolution of the alloy surface and its behavior at immersion in the SBF solution was analyzed on the basis of the Nyquist, Bode diagrams and equivalent circuits best describing the data obtained from the EIS measurements on the freshly polished and cleaned surface and after maintaining the samples immersed 0, 7, 14 and 30 days, respectively, in the SBF. These are shown in Figure 6a,b. For the freshly polished sample, in the Nyquist diagram the curve does not have a perfect semicircle but presents an additional low-frequency loop, characteristic of an inductive behavior of the electrochemical system. The presence of a negative lobe in the low-frequency range is often attributed to a process of adsorption of some species of solution on the surface of the electrode. These particles may even be solid reaction products. In the equivalent circuit of Figure 7a the presence of the negative lobe at low frequencies is marked by the inductance L, which has a relatively high value. In this equivalent circuit; Rs-represents the ohmic resistance of the electrolyte between the working electrode and the reference electrode; R 1 -the load transfer resistance through the double-electric layer (the polarization resistance); Q-the constant phase element parameter (CPE) in the impedance expression which characterizes the double-electric layer (ZCPE = Q − 1 (jω) − 1, where j = (−1) 1 2 and ω = 2 πf-angular frequency); and L and R 2 -inductance and resistance of particle layer adsorbed at the interface/electrolyte.  Table 4.
In the case of the freshly polished surface, the relatively low polarization value indicates a high corrosion rate, and the adsorption of ions from the solution and/or the soil-reaction products leads to alteration of the double-electric layer and even produces some inductive effects under the action of current low-frequency sine wave.
In the case of the sample immersed for seven days in SBF, the equivalent circuit (b) in Figure 7 is particularly simple and shapes a cell in which the delivery is due both to the kinetic process (the chemical reaction that takes place by load transfer) and to a diffusion process of loads through the product surface formed on the surface while maintaining the sample in the solution. Here, Rs is the resistance of the electrolyte, R1 represents the polarization resistance, and W is a diffusion resistance, called Warburg impedance, due to the influence of diffusion of oxidative and reducing species on the overall reaction velocity (corrosion). The constant phase element Q, which in theory should represent the capacity of the double-electric layer, is also an imperfect capacitor (n < 1), probably due to the same imperfections in the structure of the surface as for the freshly polished surface. Element values of this equivalent circuit are shown in Table 4. The equivalent circuit (c), which describes the physical state of the sample surface for the sample immersed for 14 days in the SBF as well for the sample immersed for 30 days, is characteristic of a metal coated with an imperfect, highly permeable layer.
In this circuit, Rs-the resistance of the electrolyte, R 1 and Q 1 , respectively-is the capacity that characterizes the porous or cracked layer, and R 2 and Q 2 are the strength and capacity of the double-electric layer. R 2 is actually the polarization resistance. Taking into account the numerical values of the frequency exponents (n 1 and n 2 ) presented in Table 4, it can be concluded that both the double-electric layer and the coating are not represented by ideal capacitors due to the same causes as in the case of previous samples.

Conclusions
Based on the experimental results, it is fair to think that once a new Fe-base alloy surface is exposed to a simulated body fluid solution, a complex oxide layer (FeO/MnO/SiO/CaO/MgO) immediately grows on the surface. The stability of the new layer decreased in time in the presence of the simulated body fluid and after a time period passed to the solution. Fe 3 O 4 partially changed to Fe(OH) 2 , which subdued precipitation and dissolution mechanisms. The presence of chloride on the interface metal/SBF, as shown in Table 1 (for all samples), maintained a near equilibrium state (homeostasis) between the dissolution of some compounds and the precipitation process and passing to solution. In one case, Fe(OH) 2 reacted with chloride and formed soluble FeCl 3 . After the cleaning stage, no further chloride was identified on the surface. CaO and MgO products are extremely unstable in the simulated body fluid solution. Both oxides became Ca(OH) 2 and Mg(OH) 2 and interacted on the surface with CO 2− 3 and precipitated on the surface (Table 1). It appeared that a major part of these compounds was not stable on the surface and passed to solution after the sonication cleaning stage [22]. Each time the oxide layer formed on the top of the alloy surface and came into contact with the simulated body fluid, the solution could not prevent the diffusion of the solution ions and the degradation continued until the end of the metallic material. In conclusion, the passivation layer protects the metallic surface only for a short time period and the galvanic corrosion will take place until the total dissolution of the material [23].
From the experimental results, a simple corrosion model of the FeMnSi-MgCa alloy is proposed, as shown in Figure 8. First, when the metallic material comes into contact with the solution, a complex oxide layer (FeO/MnO/SiO/MgO/CaO) grows and, at least at the beginning, protects the metallic material. The mechanisms of corrosion are presented in different articles [24][25][26][27] and the experimental results, Figures 3 and 4, are in total agreement. Second, the oxides interact with the solution and form hydroxides and grow a new layer with a lower stability (Figure 8b) that continuously interacts with chloride ions to form soluble compounds that pass to the SBF solution, as confirmed by Table 1 and Figure 1 experimental results. At the same time, the carbonate compounds attach to the alloy surface and decrease the corrosion rate because of their non-conductive nature. In the last stage, the metallic surface will have metallic material parts close to spalling, metallic material holes after the alloy passes to solution, with oxides, hydroxides, carbonates and salts on the surface as shown in Figures 1 and 2. After sonication, an important part of these compounds was removed from the surface. Further work in in vivo tests of this new material is proposed to evaluate the behavior of the material in real conditions in short, medium, or long periods. The compounds formed on the surface must be clearly established using XPS or AES (Auger electron spectroscopy) equipment to obtain a proper degradation model of the material.
We obtained a new experimental alloy based on iron with a corrosion rate (around 700 µm/year) smaller than the Mg-based alloys, but higher than the usual iron-based alloys suitable for medical applications with elements with thicknesses between 500 and 1000 µm.

•
We demonstrated that micro-alloying the FeMnSi alloy with Ca and Mg elements resulted in obtaining an α-phase microstructure in a melted state with finely distributed Ca and Mg elements. • By adding small quantities of Ca and Mg, the corrosion rate in SBF can be increased due to the formation of fine precipitates and also by changing the mechanical behavior and initial corrosion mechanism of the alloy. Further work in in vivo tests of this new material is proposed to evaluate the behavior of the material in real conditions in short, medium, or long periods. • When introducing and maintaining the FeMnSi-MgCa alloy in artificial blood plasma (SBF), the corrosion process starts from the initial moment and continues throughout the immersion period. Initially, corrosion products (possibly iron and manganese oxides) are adsorbed as microparticles on the surface of the alloy; over time, a compact layer is formed on the surface, which allows the transfer of diffusion loads. After a longer period in the solution, the compact layer deteriorates (becomes porous or cracked) and continues the corrosion in the form of crevasses.