Metropolitan Urban Mamminasata South Sulawesi, Indonesia as the object of study is explored in the core-peripheral spatial interaction towards the formation of suburban service centers. The problems raised in this study are (i) is there a relationship/correlation between spatial integration, spatial interaction, and urban agglomeration to the formation of urban activity systems and (ii) how the formation of urban activity systems works as a determinant of economic growth, land use change and environmental quality degradation towards sustainable development in the metropolitan city of Mamminasata. Comparative studies of suburban areas have been carried out over three time periods (2001, 2015 and 2019). Data elaboration on observations, surveys and documentation is done to describe urban dynamics in terms of economic, social and environmental aspects. Path analysis is used to address direct effects, indirect effects, differences, and dependencies between urban elements. The gravity model is used to analyze the spatial interactions of the core city with the periphery. The study results show that spatial integration, spatial interaction and urban agglomeration have a positive effect on the system of urban activity and economic growth in the outskirts of the Mamminasata Metropolitan area. The results of this study recommend policy makers and urban planners that land use change, spatial integration and urban spatial interactions on the spatial scale of metropolitan cities to require the implementation of sustainable development concepts oriented towards saving the environment, ensuring fairness in economic access and creating social cohesion, in line with meeting national Metropolitan city development targets by 2030.
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