Autophagy in Metabolic Age-Related Human Diseases
AbstractAutophagy is a highly conserved homeostatic cellular mechanism that mediates the degradation of damaged organelles, protein aggregates, and invading pathogens through a lysosome-dependent pathway. Over the last few years, specific functions of autophagy have been discovered in many tissues and organs; however, abnormal upregulation or downregulation of autophagy has been depicted as an attribute of a variety of pathologic conditions. In this review, we will describe the current knowledge on the role of autophagy, from its regulation to its physiological influence, in metabolic age-related disorders. Finally, we propose to discuss the therapeutic potential of pharmacological and nutritional modulators of autophagy to treat metabolic diseases. View Full-Text
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Moulis, M.; Vindis, C. Autophagy in Metabolic Age-Related Human Diseases. Cells 2018, 7, 149.
Moulis M, Vindis C. Autophagy in Metabolic Age-Related Human Diseases. Cells. 2018; 7(10):149.Chicago/Turabian Style
Moulis, Manon; Vindis, Cecile. 2018. "Autophagy in Metabolic Age-Related Human Diseases." Cells 7, no. 10: 149.
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