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Article

Assessing the Influence of Dyes Physico-Chemical Properties on Incorporation and Release Kinetics in Silk Fibroin Matrices

Department of Chemical Engineering, Institute of Environmental, Chemical and Pharmaceutical Sciences, Universidade Federal de São Paulo, Rua São Nicolau 210, Diadema 09913-030, Brazil
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Author to whom correspondence should be addressed.
Academic Editor: Luis García-Fernández
Polymers 2021, 13(5), 798; https://doi.org/10.3390/polym13050798
Received: 30 January 2021 / Revised: 26 February 2021 / Accepted: 1 March 2021 / Published: 5 March 2021
(This article belongs to the Special Issue Advanced Polymers for Biomedical Applications)
Silk fibroin (SF) is a promising and versatile biodegradable protein for biomedical applications. This study aimed to develop a prolonged release device by incorporating SF microparticles containing dyes into SF hydrogels. The influence of dyes on incorporation and release kinetics in SF based devices were evaluated regarding their hydrophilicity, molar mass, and cationic/anionic character. Hydrophobic and cationic dyes presented high encapsulation efficiency, probably related to electrostatic and hydrophobic interactions with SF. The addition of SF microparticles in SF hydrogels was an effective method to prolong the release, increasing the release time by 10-fold. View Full-Text
Keywords: biopolymer; hydrogel; microparticles; dye release biopolymer; hydrogel; microparticles; dye release
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MDPI and ACS Style

Tomoda, B.T.; Pacheco, M.S.; Abranches, Y.B.; Viganó, J.; Perrechil, F.; De Moraes, M.A. Assessing the Influence of Dyes Physico-Chemical Properties on Incorporation and Release Kinetics in Silk Fibroin Matrices. Polymers 2021, 13, 798. https://doi.org/10.3390/polym13050798

AMA Style

Tomoda BT, Pacheco MS, Abranches YB, Viganó J, Perrechil F, De Moraes MA. Assessing the Influence of Dyes Physico-Chemical Properties on Incorporation and Release Kinetics in Silk Fibroin Matrices. Polymers. 2021; 13(5):798. https://doi.org/10.3390/polym13050798

Chicago/Turabian Style

Tomoda, Bruno T., Murilo S. Pacheco, Yasmin B. Abranches, Juliane Viganó, Fabiana Perrechil, and Mariana A. De Moraes 2021. "Assessing the Influence of Dyes Physico-Chemical Properties on Incorporation and Release Kinetics in Silk Fibroin Matrices" Polymers 13, no. 5: 798. https://doi.org/10.3390/polym13050798

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