Three Component Controls in Pillared Metal-Organic Frameworks for Catalytic Carbon Dioxide Fixation

Three components of pillared metal-organic frameworks (MOFs, three components = metal ion, carboxylic acid ligand, and N-chelating ligand) were controlled for CO2 cycloaddition catalysts to synthesize organic cyclic carbonates. Among the divalent metals, Zn2+ showed the best catalytic activity, and in DABCO (1,4-diazabicyclo[2.2.2]octane)-based MOFs, hydroxy-functionalized DMOF-OH was the most efficient MOF for CO2 cycloaddition. For the BPY (4,4’-bipyridyl)-type MOFs, all five prepared BMOFs (BPY MOFs) showed similar and good conversions for CO2 cycloaddition. Finally, this pillared MOF could be recycled up to three times without activity and crystallinity loss.


Introduction
The repeating coordination bonds between metal clusters (or ions) and multi-topic ligands produce coordination polymers (CPs).When CPs have three-dimensional structures with empty pores, they are also called metal-organic frameworks (MOFs) [1,2].In the last decade, a variety of applications for utilizing the empty pores of MOFs have been developed, such as gas separation and storage, molecular shuttling and storage, sensing, etc. [3][4][5].In addition, the catalytic applications of MOFs have been intensively explored, since the pores of MOFs could allow controllable reaction sites, and each component of MOFs (metal clusters and organic ligands) could be employed as a catalytic species for organic transformations [6][7][8][9][10].
MOF-based chemical CO 2 fixation is one of the most widely studied organic transformations in a heterogeneous manner [11,12].The coupling reaction between carbon dioxide and epoxide to form organic cyclic carbonates is efficient and useful CO 2 fixation, and organic cyclic carbonates are key molecules for polar organic solvents and industrial polymerization [13].This reaction is also called the cycloaddition of CO 2 with epoxide.Various MOFs from a wide range of metal sources have been examined for the cycloaddition of CO 2 under thermal treatment, and basically, the Lewis acid site of the metal cluster in MOFs acts as a catalytic site for CO 2 and epoxide activation [11].Recently, we have investigated the effects of organic functional groups on zirconium-based MOF (i.e., UiO-66; UiO = University of Oslo) catalysts for CO 2 cycloaddition.Among the eight different functionalities, the hydroxy group showed the best catalytic conversion of CO 2 to organic cyclic carbonates under the high temperature condition (140 • C), and the non-functionalized UiO-66 showed good catalytic activity under the low temperature condition (50 • C) [14].However, the control and tuning of MOFs for CO 2 cycloaddition catalyst are mainly limited on the structural effect along with metal cation's effect or the functional group effects with same metal and frameworks.To maximize the advantage of MOF-based catalysts, the fine-tuning on ligands, pillar ligands (additional ligands), and metal cations should be studied at the same time.
Herein, we have expanded our approach to three component controls in pillared MOFs for fine-tuning MOF-based catalysts for CO 2 cycloaddition.The pillared MOF consists of two different ligands and metal clusters.The metal clusters in MOFs are also called the secondary building units (SBUs).Generally, dicarboxylic acid ligands and nitrogen-donating ligands are employed together for pillared MOF synthesis.From a structural viewpoint, the SBUs and dicarboxylate ligands form the 2D sheet, and N-donor ligands connect two 2D sheets through coordination bonds between the metal on the SBU and N-atom on the ligand (Figure 1).We have examined the effects of the metal cation in the SBU, various functional groups on the benzene-1,4-dicarboxylic acid (BDC) ligand, and the pillar ligand for CO 2 cycloaddition.The best combination of a pillared MOF for efficient catalysis of chemical CO 2 fixation has been finalized.
Catalysts 2018, 8, x FOR PEER REVIEW 2 of 11 = University of Oslo) catalysts for CO2 cycloaddition.Among the eight different functionalities, the hydroxy group showed the best catalytic conversion of CO2 to organic cyclic carbonates under the high temperature condition (140 °C), and the non-functionalized UiO-66 showed good catalytic activity under the low temperature condition (50 °C) [14].However, the control and tuning of MOFs for CO2 cycloaddition catalyst are mainly limited on the structural effect along with metal cation's effect or the functional group effects with same metal and frameworks.To maximize the advantage of MOF-based catalysts, the fine-tuning on ligands, pillar ligands (additional ligands), and metal cations should be studied at the same time.
Herein, we have expanded our approach to three component controls in pillared MOFs for finetuning MOF-based catalysts for CO2 cycloaddition.The pillared MOF consists of two different ligands and metal clusters.The metal clusters in MOFs are also called the secondary building units (SBUs).Generally, dicarboxylic acid ligands and nitrogen-donating ligands are employed together for pillared MOF synthesis.From a structural viewpoint, the SBUs and dicarboxylate ligands form the 2D sheet, and N-donor ligands connect two 2D sheets through coordination bonds between the metal on the SBU and N-atom on the ligand (Figure 1).We have examined the effects of the metal cation in the SBU, various functional groups on the benzene-1,4-dicarboxylic acid (BDC) ligand, and the pillar ligand for CO2 cycloaddition.The best combination of a pillared MOF for efficient catalysis of chemical CO2 fixation has been finalized.
Propylene oxide (1a) was employed as a model substrate to react with CO 2 (under 10 bar) in the presence of DMOF and ammonium salt co-catalysts without additional solvent (Table 1).The zinc-based DMOF (DMOF(Zn)) was used for the first trial of a MOF catalyst in this study, since DMOF(Zn) is common for functionalization with ligands.Whereas a low conversion was obtained with DMOF(Zn) alone (8%, entry 1, Table 1), the addition of a co-catalyst salt provided increased reactivity under 100 • C for 3 h.Among the five ammonium and phosphonium salts with various halides (TBAI, tetra-n-butylammonium iodide; TBABr, tetra-n-butylammonium bromide; TBACl, tetra-n-butylammonium chloride; TBPBr, tetra-n-butylphosphonium bromide; and PPNCl, bis(triphenylphosphine)iminium chloride), TBABr showed the best efficiency (entries 2-6, Table 1).Only 33% conversion was observed (entry 7, Table 1) when the co-catalyst TBABr was employed alone.The effect of the metal cation on CO2 cycloaddition was examined next.A series of DMOFs with different metal salts (e.g., Co, Ni, Cu, and Zn) were prepared following the reported procedures (see the experimental section and supplementary information for details).All of the DMOFs from Co, Ni, Cu and Zn showed identical structures and matched with previously reported pillared MOF structures, as indicated by powder X-ray diffraction (PXRD) patterns (Figure 2).Under the optimized reaction conditions (100 °C, 1 mol% TBABr) with a shortened reaction time (2 h) to display reactivity differences better, DMOF(Zn) showed the best conversion (entry 8, Table 1), and the catalytic efficiency decreased according to the following sequence: DMOF(Co) > DMOF(Ni) > DMOF(Cu) (entries 9-11, Table 1), which is exactly the same trend recently reported by Verpoort's group.In their study, DMOFs from different metals were employed for CO2 cycloaddition without co-catalysts [19].With DMOF(Zn) and the optimized conditions, the effect of the functional group on the BDC ligand was studied next ( The effect of the metal cation on CO 2 cycloaddition was examined next.A series of DMOFs with different metal salts (e.g., Co, Ni, Cu, and Zn) were prepared following the reported procedures (see the experimental section and supplementary information for details).All of the DMOFs from Co, Ni, Cu and Zn showed identical structures and matched with previously reported pillared MOF structures, as indicated by powder X-ray diffraction (PXRD) patterns (Figure 2).Under the optimized reaction conditions (100 • C, 1 mol% TBABr) with a shortened reaction time (2 h) to display reactivity differences better, DMOF(Zn) showed the best conversion (entry 8, Table 1), and the catalytic efficiency decreased according to the following sequence: DMOF(Co) > DMOF(Ni) > DMOF(Cu) (entries 9-11, Table 1), which is exactly the same trend recently reported by Verpoort's group.In their study, DMOFs from different metals were employed for CO 2 cycloaddition without co-catalysts [19].The effect of the metal cation on CO2 cycloaddition was examined next.A series of DMOFs with different metal salts (e.g., Co, Ni, Cu, and Zn) were prepared following the reported procedures (see the experimental section and supplementary information for details).All of the DMOFs from Co, Ni, Cu and Zn showed identical structures and matched with previously reported pillared MOF structures, as indicated by powder X-ray diffraction (PXRD) patterns (Figure 2).Under the optimized reaction conditions (100 °C, 1 mol% TBABr) with a shortened reaction time (2 h) to display reactivity differences better, DMOF(Zn) showed the best conversion (entry 8, Table 1), and the catalytic efficiency decreased according to the following sequence: DMOF(Co) > DMOF(Ni) > DMOF(Cu) (entries 9-11, Table 1), which is exactly the same trend recently reported by Verpoort's group.In their study, DMOFs from different metals were employed for CO2 cycloaddition without co-catalysts [19].With DMOF(Zn) and the optimized conditions, the effect of the functional group on the BDC ligand was studied next (Table 2).We have prepared five different DMOF(Zn)s with different BDC With DMOF(Zn) and the optimized conditions, the effect of the functional group on the BDC ligand was studied next (Table 2).We have prepared five different DMOF(Zn)s with different BDC ligands, such as BDC, BDC-NH 2 (2-aminobenzene-1,4-dicarboxylic acid), BDC-OH (2-hydroxybenzene-1,4-dicarboxylic acid), 1,4-NDC (naphthalene-1,4-dicarboxylic acid), and 2,6-NDC (naphthalene-2,6-dicarboxylic acid, see the supplementary information for details).DMOF(Zn), DMOF(Zn)-NH 2 , DMOF(Zn)-OH, and DMOF(Zn)-1,4-NDC showed identical structures and matched well with the reported structures, which was demonstrated by PXRD (Figure 3) [20][21][22].Only DMOF(Zn)-2,6-NDC showed a little different pattern, since the two dicarboxylic acids were a slightly tilted from the other BDC ligands.However, they are all still in the same framework and have the empirical formula Zn 2 (BDC) 2 (DABCO), as indicated by 1 H NMR (Nuclear Magnetic Resonance) after acid digestion (Figures S1-S5 in the Supplementary Information).And the crystal size was determined by microscope, since DMOFs were obtained as large single crystals.Around 0.5-2 mm size transparent crystals were synthesized from the solvothermal condition (Figure S6).  3) [20][21][22].
Only DMOF(Zn)-2,6-NDC showed a little different pattern, since the two dicarboxylic acids were a slightly tilted from the other BDC ligands.However, they are all still in the same framework and have the empirical formula Zn2(BDC)2(DABCO), as indicated by 1 H NMR (Nuclear Magnetic Resonance) after acid digestion (Figures S1-S5 in the Supplementary Information).And the crystal size was determined by microscope, since DMOFs were obtained as large single crystals.Around 0.5-2 mm size transparent crystals were synthesized from the solvothermal condition (Figure S6).Among the five DMOF(Zn)s, the hydroxy-functionalized DMOF(Zn)-OH showed the best conversion for CO2 cycloaddition with 1a (83%, entry 2 in Table 2).The selectivity for cyclic carbonate synthesis versus polymerization was also measured by 1  Only DMOF(Zn)-2,6-NDC showed a little different pattern, since the two dicarboxylic acids were a slightly tilted from the other BDC ligands.However, they are all still in the same framework and have the empirical formula Zn2(BDC)2(DABCO), as indicated by 1 H NMR (Nuclear Magnetic Resonance) after acid digestion (Figures S1-S5 in the Supplementary Information).And the crystal size was determined by microscope, since DMOFs were obtained as large single crystals.Around 0.5-2 mm size transparent crystals were synthesized from the solvothermal condition (Figure S6).Among the five DMOF(Zn)s, the hydroxy-functionalized DMOF(Zn)-OH showed the best conversion for CO2 cycloaddition with 1a (83%, entry 2 in Table 2).The selectivity for cyclic carbonate synthesis versus polymerization was also measured by 1  Among the five DMOF(Zn)s, the hydroxy-functionalized DMOF(Zn)-OH showed the best conversion for CO 2 cycloaddition with 1a (83%, entry 2 in Table 2).The selectivity for cyclic carbonate synthesis versus polymerization was also measured by 1 H NMR, and no polycarbonates were detected.The amino-functionalized DMOF(Zn)-NH 2 also displayed good catalytic efficiency under the optimized conditions (75%, entry 1 in Table 2).This finding is quite relevant to a previous Catalysts 2018, 8, 565 5 of 11 study on the effects of functional groups on a zirconium-based MOF for CO 2 cycloaddition.In the case of the Zr-MOF, the hydroxy-group was also the best catalyst at high temperature (140 • C) in the presence of a co-catalyst, TBAI (tetra-n-butylammonium iodide) [14].
For the last part of MOF catalyst tuning, we introduced a 4,4'-bipyridyl (BPY) ligand as a pillar ligand, which is longer than DABCO.This type of MOF is also known as BMOF (BPY-MOF), and it has a similar empirical formula M 2 (BDC) 2 (BPY) [23,24].We fixed the metal part to be Zn and controlled the functional group on ligands with BPY pillar.A series of BMOFs, such as BMOF(Zn), BMOF(Zn)-NH 2 , BMOF(Zn)-OH, BMOF(Zn)-1,4-NDC, and BMOF(Zn)-2,6-NDC, were obtained by following the reported procedures or modified methods (see the supplementary information for details).BMOF(Zn) and BMOF(Zn)-NH 2 showed identical structures, as indicated by PXRD (Figure 4), which matched well with the reported structures for BMOF(Zn)-1,4-NDC and BMOF(Zn)-2,6-NDC.The 1 H NMR after acid digestion revealed the formulas of the BMOF(Zn)s, except BMOF(Zn)-OH is Zn 2 (BDC-R) 2 (BPY) (Figures S7-S11 in the supplementary information).Since the particle size of BMOF(Zn)s were smaller than DMOF(Zn)s, Scanning Electron Microscope (SEM) images were obtained and analyzed for particle size.BMOF(Zn), BMOF(Zn)-NH 2 , and BMOF(Zn)-1,4-NDC showed particles size with ~200 µm size, and BMOF(Zn)-2,6-NDC showed smaller particle size with ~50 µm.Lastly, BMOF(Zn)-OH has needle type crystals with ~200 µm length and ~20 µm width (Figure S12).Interestingly, there are no reported structures for BMOF(Zn)-OH in the literature, and thus we have confirmed the structure of BMOF(Zn)-OH by single X-ray crystallography (see the supplementary information for details, Tables S1 and S2) and measured gas sorption property along with thermal stability.Surprisingly, BMOF(Zn)-OH showed a different structure compared with the other BMOF(Zn)s.Four 4,4'-BPY ligands were coordinated with the Zn 2 -SBU at the same time (Figure S13).Based on the structural analysis, the empirical formula of BMOF(Zn)-OH is Zn 2 (BDC-OH)(BPY), and the hydroxy group, due to its role in hydrogen bonding with the Zn 2 SBU, leads to this structural change.Brunauer-Emmett-Teller (BET) surface area is calculated for 70 m 2 /g, which is lower porosity than reported BMOF(Zn)-2,6-NDC (Table S3).Full N 2 isotherm also performed at 77 K and displayed a hysteresis on a range between 0.4-1.0relative pressure, as shown in Figure S14.Last, the thermal stability of BMOF(Zn)-OH was measured by thermogravimetric analysis (TGA).New material is thermal stable up to >200 • C and showed 80% weight loss at 500 • C (Figure S15).
Catalysts 2018, 8, x FOR PEER REVIEW 5 of 11 the optimized conditions (75%, entry 1 in Table 2).This finding is quite relevant to a previous study on the effects of functional groups on a zirconium-based MOF for CO2 cycloaddition.In the case of the Zr-MOF, the hydroxy-group was also the best catalyst at high temperature (140 °C) in the presence of a co-catalyst, TBAI (tetra-n-butylammonium iodide) [14].
For the last part of MOF catalyst tuning, we introduced a 4,4'-bipyridyl (BPY) ligand as a pillar ligand, which is longer than DABCO.This type of MOF is also known as BMOF (BPY-MOF), and it has a similar empirical formula M2(BDC)2(BPY) [23,24].We fixed the metal part to be Zn and controlled the functional group on ligands with BPY pillar.A series of BMOFs, such as BMOF(Zn), BMOF(Zn)-NH2, BMOF(Zn)-OH, BMOF(Zn)-1,4-NDC, and BMOF(Zn)-2,6-NDC, were obtained by following the reported procedures or modified methods (see the supplementary information for details).BMOF(Zn) and BMOF(Zn)-NH2 showed identical structures, as indicated by PXRD (Figure 4), which matched well with the reported structures for BMOF(Zn)-1,4-NDC and BMOF(Zn)-2,6-NDC.The 1 H NMR after acid digestion revealed the formulas of the BMOF(Zn)s, except BMOF(Zn)-OH is Zn2(BDC-R)2(BPY) (Figures S7-S11 in the Supplementary Information).Since the particle size of BMOF(Zn)s were smaller than DMOF(Zn)s, Scanning Electron Microscope (SEM) images were obtained and analyzed for particle size.BMOF(Zn), BMOF(Zn)-NH2, and BMOF(Zn)-1,4-NDC showed particles size with ~200 μm size, and BMOF(Zn)-2,6-NDC showed smaller particle size with ~50 μm.Lastly, BMOF(Zn)-OH has needle type crystals with ~200 μm length and ~20 μm width (Figure S12).Interestingly, there are no reported structures for BMOF(Zn)-OH in the literature, and thus we have confirmed the structure of BMOF(Zn)-OH by single X-ray crystallography (see the supplementary information for details, Tables S1 and S2) and measured gas sorption property along with thermal stability.Surprisingly, BMOF(Zn)-OH showed a different structure compared with the other BMOF(Zn)s.Four 4,4'-BPY ligands were coordinated with the Zn2-SBU at the same time (Figure S13).Based on the structural analysis, the empirical formula of BMOF(Zn)-OH is Zn2(BDC-OH)(BPY), and the hydroxy group, due to its role in hydrogen bonding with the Zn2 SBU, leads to this structural change.Brunauer-Emmett-Teller (BET) surface area is calculated for 70 m 2 /g, which is lower porosity than reported BMOF(Zn)-2,6-NDC (Table S3).Full N2 isotherm also performed at 77 K and displayed a hysteresis on a range between 0.4-1.0relative pressure, as shown in Figure S14.Last, the thermal stability of BMOF(Zn)-OH was measured by thermogravimetric analysis (TGA).New material is thermal stable up to >200 °C and showed 80% weight loss at 500 °C (Figure S15).From the study with BMOF(Zn)s evaluating the effects of the functional group, all five-functionalized BMOF(Zn)s displayed very similar catalytic activities for CO 2 cycloaddition (from 75% to 80%, Table 3).We assumed that in the BMOF(Zn) system, the Lewis acidity of zinc ions in the SBU and BPY had a more significant effect than the BDC ligand part on the CO 2 cycloaddition.Since the ligand accessibility and synthetic efficiency of BMOF(Zn)-NH 2 is much higher than those of the other BMOF(Zn)s, next, the substrate scopes were investigated with the BMOF(Zn)-NH 2 catalyst (Scheme 1).Alkyl chain-containing butylene oxide and hexylene oxide (i.e., 1,2-epoxybutane (1b) and 1,2-epoxyhexane (1c)) along with heteroatom-containing (i.e., O and Cl) 1,2-ethoxy-3-methoxypropane (1d) and epichlorohydrin (1e) were successfully coupled with CO 2 to the corresponding cyclic carbonates with good to excellent yields (71-84%) under the optimized conditions.In case of the simple PO (1a) case, 78% yield under 100 • C for 2 h is generally competitive than other MOF conditions with relatively short reaction time (<2 h).Lewis acidic zirconium-based UiO-66 showed 66% under 100 • C for 2 h with PO (1a) [14].Other zinc and BPY-based UMCM-15 is working at room temperature for CO 2 cycloaddition, however longer reaction time (>16 h) is necessary for >90% conversion [25].In case of cobalt-BPY type MOF, cyclic carbonate synthesis from PO (1a) with >90% conversion was obtained under 100 • C for 8 h condition [26].Next, less reactive di-substituted epoxides were tested for the cycloaddition.1,2-Epoxy-2-methylpropane (1f) and cyclohexene oxide (1g) showed relatively low conversion (17% for 2f and 23% for 2g, respectively).The obtained products were confirmed by 1 H and 13 C NMR (see the supplementary information for details), and once again, the polymerized byproduct was not detected in all substrates.From the study with BMOF(Zn)s evaluating the effects of the functional group, all fivefunctionalized BMOF(Zn)s displayed very similar catalytic activities for CO2 cycloaddition (from 75% to 80%, Table 3).We assumed that in the BMOF(Zn) system, the Lewis acidity of zinc ions in the SBU and BPY had a more significant effect than the BDC ligand part on the CO2 cycloaddition.Since the ligand accessibility and synthetic efficiency of BMOF(Zn)-NH2 is much higher than those of the other BMOF(Zn)s, next, the substrate scopes were investigated with the BMOF(Zn)-NH2 catalyst (Scheme 1).Alkyl chain-containing butylene oxide and hexylene oxide (i.e., 1,2-epoxybutane (1b) and 1,2epoxyhexane (1c)) along with heteroatom-containing (i.e., O and Cl) 1,2-ethoxy-3-methoxypropane (1d) and epichlorohydrin (1e) were successfully coupled with CO2 to the corresponding cyclic carbonates with good to excellent yields (71-84%) under the optimized conditions.In case of the simple PO (1a) case, 78% yield under 100 °C for 2 h is generally competitive than other MOF conditions with relatively short reaction time (<2 h).Lewis acidic zirconium-based UiO-66 showed 66% under 100 °C for 2 h with PO (1a) [14].Other zinc and BPY-based UMCM-15 is working at room temperature for CO2 cycloaddition, however longer reaction time (>16 h) is necessary for >90% conversion [25].In case of cobalt-BPY type MOF, cyclic carbonate synthesis from PO (1a) with >90% conversion was obtained under 100 °C for 8 h condition [26].Next, less reactive di-substituted epoxides were tested for the cycloaddition.1,2-Epoxy-2-methylpropane (1f) and cyclohexene oxide (1g) showed relatively low conversion (17% for 2f and 23% for 2g, respectively).The obtained ( 2 mo l % ) TBAB r ( 1 mo l % ) Lastly, the reusability test was performed using the BMOF(Zn)-NH 2 catalyst at 100 • C for 2 h with 1a.After each cycloaddition reaction, the BMOF(Zn)-NH 2 catalyst was recovered by centrifugation and filtered as a powder, since the crystal was ground by the stir-bar in the reaction vessel.The obtained powder form of BMOF(Zn)-NH 2 after the first and third cycles also showed similar PXRD patterns with the pristine material (Figure S16).And the reactivity of BMOF(Zn)-NH 2 was generally retained by reuse, with values of 75%, respectively (Table S4).This is a somewhat surprising finding because the physical and chemical stabilities of Zn-based pillar MOFs are relatively lower than early transition metal-based MOFs, such as Zr-based MOFs [14,27,28].
A possible reaction mechanism for pillared MOF-catalyzed CO 2 cycloaddition was proposed in the Scheme 2 based on our findings and related references [25,26].The halide (e.g., bromide) nucleophile from ammonium salt is a key component for the ring-opening of epoxide, and Lewis acidic site on metal SBU could activate the ring-opening of epoxide [14].The basic site on pillar ligand will coordinate and activate CO 2 molecule [25,26].These types of synergic effects between the Lewis acidic sites on metal clusters and basic sites on ligand were previously studied for the cycloaddition reaction in heterogeneous catalysis and ionic liquid [29][30][31].Lastly, the reusability test was performed using the BMOF(Zn)-NH2 catalyst at 100 °C for 2 h with 1a.After each cycloaddition reaction, the BMOF(Zn)-NH2 catalyst was recovered by centrifugation and filtered as a powder, since the crystal was ground by the stir-bar in the reaction vessel.The obtained powder form of BMOF(Zn)-NH2 after the first and third cycles also showed similar PXRD patterns with the pristine material (Figure S16).And the reactivity of BMOF(Zn)-NH2 was generally retained by reuse, with values of 75%, respectively (Table S4).This is a somewhat surprising finding because the physical and chemical stabilities of Zn-based pillar MOFs are relatively lower than early transition metal-based MOFs, such as Zr-based MOFs [14,27,28].
A possible reaction mechanism for pillared MOF-catalyzed CO2 cycloaddition was proposed in the Scheme 2 based on our findings and related references [25,26].The halide (e.g., bromide) nucleophile from ammonium salt is a key component for the ring-opening of epoxide, and Lewis acidic site on metal SBU could activate the ring-opening of epoxide [14].The basic site on pillar ligand will coordinate and activate CO2 molecule [25,26].These types of synergic effects between the Lewis acidic sites on metal clusters and basic sites on ligand were previously studied for the cycloaddition reaction in heterogeneous catalysis and ionic liquid [29][30][31].
3.2.Synthesis of DMOF(M)s (M: Zn, Cu, Co, Ni) DMOF(M) was prepared by following a reported method with some modifications (see the supplementary file for details).Metal nitrate (0.20 mmol), BDC ligand (0.20 mmol), DABCO (0.32 mmol) and DMF (4 mL) were placed in a flask.After stirring for 10 min, a white gel was formed.This gel was filtered using a fine porosity glass filter.The clear solution was then transferred to a 20 mL size scintillation vial and heated at 120 • C for 48 h.The resulting crystals were then washed three times with 5 mL of DMF.The solvent was then exchanged with CHCl 3 (3 times), and CHCl 3 was replaced with fresh CHCl 3 every 24 h (3 times).

Synthesis of Functionalized DMOFs
DMOF(Zn)-R was prepared by following a reported procedure with the target ligand, but with slight modifications (see the supplementary file for details) [33].Zn(NO 3 ) 2 •6H 2 O (59 mg, 0.20 mmol), BDC-R ligand (0.20 mmol), DABCO (36 mg, 0.32 mmol) and DMF (5 mL) were placed in a flask.After stirring for 10 min, the gel was formed.This gel was filtered, and the clear solution was transferred to a 20 mL scintillation vial and heated to 100 • C at a rate of 2.5 • C/min.The temperature was then held for 12 h (at 100 • C), followed by cooling to room temperature at a rate of 2.5 • C/min.The resulting crystals were washed three times with 5 mL of DMF, and the solvent was exchanged with CHCl 3 (3 times), with the CHCl 3 replaced every 24 h (3 times).

Conclusions
The three-component controls in pillared MOFs have been studied for the catalytic CO 2 cycloaddition reaction.Among the various divalent metal sources, Zn(II) displayed the best activity with the existence of ammonium halide co-catalyst at 100 • C. In the case of DABCO-type pillared MOFs, for the DMOF series, the hydroxy group-containing DMOF(Zn)-OH showed the best catalytic activity for CO 2 cycloaddition with PO.For the longer BPY-type pillared MOFs, the functional group in the BDC ligand did not have a significant effect on the CO 2 cycloaddition.Various epoxides were successfully converted to organic cyclic carbonates under the optimized conditions (yields of 71-84%), and finally pillared MOF, BMOF(Zn)-NH 2 could be recycled up to three times without activity and crystallinity loss.

Author Contributions:
Conceptualization, M.H.P., Y.K. and M.K; Investigation, J.N., D.K., J.L. and M.Y.; Characterization, J.N. and K.M.L.; Writing-Original Draft Preparation, J.N. and M.K.; Supervision, K.M.L., Y.K. and M.K. Funding: This work was supported by the Korea Institute of Energy Technology Evaluation and Planning (KETEP) and the Ministry of Trade, Industry and Energy (MOTIE) of the Republic of Korea (No. 20172010202000).

Table 1 .
Reaction condition screening and metal effects.

Table 1 .
Reaction condition screening and metal effects.

Table 2
).We have prepared five different DMOF(Zn)s with different BDC

Table 1 .
Reaction condition screening and metal effects.