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Open AccessEditorial
Cancers 2011, 3(3), 2886-2887;

Current Concepts of Metastasis Formation

Comprehensive Cancer Center Muenster, University Hospital Muenster, Albert-Schweitzer-Campus 1, 48149 Muenster, Germany
Author to whom correspondence should be addressed.
Received: 6 July 2011 / Accepted: 12 July 2011 / Published: 13 July 2011
(This article belongs to the Special Issue Organ-Specific Metastasis Formation)
Full-Text   |   PDF [138 KB, uploaded 13 July 2011]
Note: In lieu of an abstract, this is an excerpt from the first page.


The development of secondary distant organ and lymph node metastasis has an extraordinary impact on the prognosis of patients with solid cancer. In most cases the advent of metastatic growth represents the turning point from a local, potentially curable, disease to a systemic non-curable situation. As a highly regulated process, metastasis formation follows a distinct, non-random pattern characteristic for each tumor entity. Metastasis formation and strategies to prevent this lethal event in the progression of cancer is of fundamental interest for cancer science and patient care. In this special issue of Cancers, papers highlighting cellular mechanisms of metastasis formation, genetic and epigenetic aspects associated with organ and tumor specific metastasis formation, as well as papers outlining experimental and clinical therapeutic concepts for anti-metastatic treatment are included. [...] View Full-Text
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Haier, J.; Gassman, P. Current Concepts of Metastasis Formation. Cancers 2011, 3, 2886-2887.

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