Possible DNA Viral Factors of Human Breast Cancer
Abstract
:1. Introduction
Gene/ virus | Sporadic breast cancer | Familial breast-ovarian cancer | Family breast cancer |
---|---|---|---|
Gene | |||
BRCA1 | 0 | 10–40% | 1–11% |
BRCA2 | 1.5% | 5–15% | 5–15% |
P53 | 20.3% | ||
Virus | |||
HPV | 12.9% | ||
HSV-1 | 12.9% | ||
HSV-2 | 0 | ||
EBV | 45.2% | ||
HCMV | 75.8% | ||
HHV-8 | 43.8% |
2. HPV
3. HSV
4. EBV
5. HCMV
6. HHV-8
7. A Possibility of Multiple Viral Factors Involved in Breast Cancer
Virus | Breast cancer | Oncogenic potential/associated virus | |||||
---|---|---|---|---|---|---|---|
Overall survival | Relapse-free survival | Breast cancer | Fibroadenoma | Thyroid tumor | Cervical cancer | Oral cancer | |
HPV | + | - | - | - | - | +1 | +1 |
HSV-1 | + | - | - | +1 | - | - | +2 |
HSV-2 | N.A. | N.A. | - | - | - | +3 | - |
EBV | + | - | +2 | +2 | - | - | - |
HCMV | + | + | - | - | + | +2 | - |
HHV-8 | + | + | +1 | +1 | - | - | - |
8. Conclusions
References
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Hsu, C.-R.; Lu, T.-M.; Chin, L.W.; Yang, C.-C. Possible DNA Viral Factors of Human Breast Cancer. Cancers 2010, 2, 498-512. https://doi.org/10.3390/cancers2020498
Hsu C-R, Lu T-M, Chin LW, Yang C-C. Possible DNA Viral Factors of Human Breast Cancer. Cancers. 2010; 2(2):498-512. https://doi.org/10.3390/cancers2020498
Chicago/Turabian StyleHsu, Chun-Ru, Tsong-Ming Lu, Lengsu William Chin, and Chi-Chiang Yang. 2010. "Possible DNA Viral Factors of Human Breast Cancer" Cancers 2, no. 2: 498-512. https://doi.org/10.3390/cancers2020498