Next Article in Journal
Identification of Nucleolin as a Novel AEG-1-Interacting Protein in Breast Cancer via Interactome Profiling
Next Article in Special Issue
Skeletal Muscle Loss and Octogenarian Status Are Associated with S-1 Adjuvant Therapy Discontinuation and Poor Prognosis after Pancreatectomy
Previous Article in Journal
Trend Shifts in Age-Specific Incidence for In Situ and Invasive Cutaneous Melanoma in Sweden
Previous Article in Special Issue
Perioperative Predictors of Early Recurrence for Resectable and Borderline-Resectable Pancreatic Cancer
Article

Hyperspectral Imaging (HSI)—A New Tool to Estimate the Perfusion of Upper Abdominal Organs during Pancreatoduodenectomy

1
Department of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of Leipzig, Liebigstr. 20, D-04103 Leipzig, Germany
2
Innovation Center Computer Assisted Surgery (ICCAS), University of Leipzig, D-04103 Leipzig, Germany
3
Department of Diagnostic and Interventional Radiology, University Hospital of Leipzig, D-04103 Leipzig, Germany
*
Author to whom correspondence should be addressed.
These authors contributed equally as first authors.
These authors contributed equally as last authors.
Academic Editor: Tsutomu Fujii
Cancers 2021, 13(11), 2846; https://doi.org/10.3390/cancers13112846
Received: 18 April 2021 / Revised: 20 May 2021 / Accepted: 25 May 2021 / Published: 7 June 2021
(This article belongs to the Special Issue Recent Highly Advanced Surgery for Pancreatic Cancer)
Novel intraoperative imaging systems may have a critical impact on intraoperative decision-making. Hyperspectral imaging (HSI) is one of the leading new imaging systems, providing color pictures of tissue characterization, such as oxygen saturation (StO2) and Near-Infrared Perfusion Index (NIR-PI). Several surgical disciplines have already used HSI in detecting tissue perfusion with a proven record of success. To the best of our knowledge, HSI has not been used in the field of pancreatic surgery yet.
Hyperspectral imaging (HSI) in abdominal surgery is a new non-invasive tool for the assessment of the perfusion and oxygenation of various tissues and organs. Its benefit in pancreatic surgery is still unknown. The aim of this study was to evaluate the key impact of using HSI during pancreatoduodenectomy (PD). In total, 20 consecutive patients were included. HSI was recorded during surgery as part of a pilot study approved by the local Ethics Committee. Data were collected prospectively with the TIVITA® Tissue System. Intraoperative HS images were recorded before and after gastroduodenal artery (GDA) clamping. We detected four patients with celiac artery stenosis (CAS) caused by a median arcuate ligament (MAL). In two of these patients, a reduction in liver oxygenation (StO2) was discovered 15 and 30 min after GDA clamping. The MAL was divided in these patients. HSI showed an improvement of liver StO2 after MAL division (from 61% to 73%) in one of these two patients. There was no obvious decrease in liver StO2 in the other two patients with CAS. HSI, as a non-invasive procedure, could be helpful in evaluating liver and gastric perfusion during PD, which might assist surgeons in choosing the best surgical approach and in improving patients’ outcomes. View Full-Text
Keywords: hyperspectral imaging (HSI); pancreatoduodenectomy (PD); celiac artery stenosis (CAS) hyperspectral imaging (HSI); pancreatoduodenectomy (PD); celiac artery stenosis (CAS)
Show Figures

Graphical abstract

MDPI and ACS Style

Moulla, Y.; Buchloh, D.C.; Köhler, H.; Rademacher, S.; Denecke, T.; Meyer, H.-J.; Mehdorn, M.; Lange, U.G.; Sucher, R.; Seehofer, D.; Jansen-Winkeln, B.; Gockel, I. Hyperspectral Imaging (HSI)—A New Tool to Estimate the Perfusion of Upper Abdominal Organs during Pancreatoduodenectomy. Cancers 2021, 13, 2846. https://doi.org/10.3390/cancers13112846

AMA Style

Moulla Y, Buchloh DC, Köhler H, Rademacher S, Denecke T, Meyer H-J, Mehdorn M, Lange UG, Sucher R, Seehofer D, Jansen-Winkeln B, Gockel I. Hyperspectral Imaging (HSI)—A New Tool to Estimate the Perfusion of Upper Abdominal Organs during Pancreatoduodenectomy. Cancers. 2021; 13(11):2846. https://doi.org/10.3390/cancers13112846

Chicago/Turabian Style

Moulla, Yusef, Dorina C. Buchloh, Hannes Köhler, Sebastian Rademacher, Timm Denecke, Hans-Jonas Meyer, Matthias Mehdorn, Undine G. Lange, Robert Sucher, Daniel Seehofer, Boris Jansen-Winkeln, and Ines Gockel. 2021. "Hyperspectral Imaging (HSI)—A New Tool to Estimate the Perfusion of Upper Abdominal Organs during Pancreatoduodenectomy" Cancers 13, no. 11: 2846. https://doi.org/10.3390/cancers13112846

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop