Cytostretch, an Organ-on-Chip Platform
Abstract
:1. Introduction
2. Cytostretch Membrane Product Platform
Fabrication
3. Through-Membrane Micro-Pores
3.1. Fabrication
3.2. Characterization
3.3. Results and Discussion
4. Micro-Electrode Array
4.1. Fabrication
4.2. Characterization
4.3. Results and Discussion
5. Micro-Grooves
5.1. Fabrication
5.2. Characterization
5.3. Results and Discussion
6. Strain Gauges
6.1. Fabrication
6.2. Characterization
6.3. Results and Discussion
7. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
Abbreviations
OOC | Organ-on-Chip |
PDMS | Polydimethylsiloxane |
hPSC | Human Pluripotent Stem Cell |
hPSC-CM | hPSC Derived Cardiomyocytes |
SEM | Scanning Electron Microscopy |
MEA | Micro-Electrode Array |
ECM | Extra Cellular Matrix |
PR | PhotoResist |
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Gaio, N.; Van Meer, B.; Quirós Solano, W.; Bergers, L.; Van de Stolpe, A.; Mummery, C.; Sarro, P.M.; Dekker, R. Cytostretch, an Organ-on-Chip Platform. Micromachines 2016, 7, 120. https://doi.org/10.3390/mi7070120
Gaio N, Van Meer B, Quirós Solano W, Bergers L, Van de Stolpe A, Mummery C, Sarro PM, Dekker R. Cytostretch, an Organ-on-Chip Platform. Micromachines. 2016; 7(7):120. https://doi.org/10.3390/mi7070120
Chicago/Turabian StyleGaio, Nikolas, Berend Van Meer, William Quirós Solano, Lambert Bergers, Anja Van de Stolpe, Christine Mummery, Pasqualina M. Sarro, and Ronald Dekker. 2016. "Cytostretch, an Organ-on-Chip Platform" Micromachines 7, no. 7: 120. https://doi.org/10.3390/mi7070120