Next Article in Journal
Dietary Factors Modulate Iron Uptake in Caco-2 Cells from an Iron Ingot Used as a Home Fortificant to Prevent Iron Deficiency
Previous Article in Journal
Effect of Oral Pre-Meal Administration of Betaglucans on Glycaemic Control and Variability in Subjects with Type 1 Diabetes
Open AccessArticle

A Micronutrient Fortified Beverage Given at Different Dosing Frequencies Had Limited Impact on Anemia and Micronutrient Status in Filipino Schoolchildren

1
Food and Nutrition Research Institute, Department of Science and Technology, 1632 Taguig, Philippines
2
Formerly with the Global Alliance for Improved Nutrition (GAIN), Rue de Varembre 7, 1202 Geneve, Switzerland
3
Global Scientific and Regulatory Affairs, The Coca-Cola Company, Atlanta, GA 30301, USA
4
Baylor College of Medicine, Departments of Internal Medicine, Pediatrics, Global Initiatives, and Center for Space Medicine, Houston, TX 77030, USA
5
University of Toronto, Center for Global Child Health, The Hospital for Sick Children, Toronto, ON M6S 1S6, Canada
*
Author to whom correspondence should be addressed.
Nutrients 2017, 9(9), 1002; https://doi.org/10.3390/nu9091002
Received: 29 June 2017 / Revised: 22 August 2017 / Accepted: 24 August 2017 / Published: 12 September 2017
This study evaluated the effects of a multi-micronutrient fortified juice drink given in different frequencies of consumption on hemoglobin (Hb) concentration of schoolchildren. Hb was measured in 2423 schoolchildren aged 6- to 9-years-old at baseline. All anemic children (n = 246) were randomly allocated into groups: Daily dose (HD: high dose), 5X/week (MD: Moderate Dose), 3X/week (LD: Low Dose) and unfortified (Control). Pre- and post-study measurements of micronutrients were collected from 228 children. At the endpoint, significant Hb increases were observed in all groups, but there was no significant difference between groups. There was a significant reduction in anemia prevalence in all groups from 100% to 36% (Control), 30% (LD), 23% (MD) and 26% (HD). No dose-response effect was observed in Hb in this population. Most likely, this resulted from better than expected micronutrient status and lower than expected severity of anemia and micronutrient deficiencies in this cohort. It is unlikely that the addition of a fortified beverage to school feeding programs in this population would have a positive impact. Whether such an intervention would be cost-effective as a preventative approach needs to be assessed. This study demonstrates the importance of targeting such interventions to appropriate populations. View Full-Text
Keywords: hemoglobin 1; dose response 2; multi-nutrient fortified juice drink 3 hemoglobin 1; dose response 2; multi-nutrient fortified juice drink 3
Show Figures

Figure 1

MDPI and ACS Style

Angeles-Agdeppa, I.; Magsadia, C.R.; Aaron, G.J.; Lloyd, B.B.; Hilmers, D.C.; Bhutta, Z.A. A Micronutrient Fortified Beverage Given at Different Dosing Frequencies Had Limited Impact on Anemia and Micronutrient Status in Filipino Schoolchildren. Nutrients 2017, 9, 1002.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop