Virology, Epidemiology, Pathogenesis, and Control of COVID-19
Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China
School of Public Health, Xinxiang Medical University, Xinxiang 453003, China
Department of Immunology, Duke University Medical Center, Durham, NC 27710, USA
Author to whom correspondence should be addressed.
Viruses 2020, 12(4), 372; https://doi.org/10.3390/v12040372
Received: 7 March 2020 / Revised: 25 March 2020 / Accepted: 26 March 2020 / Published: 27 March 2020
(This article belongs to the Special Issue Pathogenesis of Human and Animal Coronaviruses)
The outbreak of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) in China has been brought to global attention and declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Scientific advancements since the pandemic of severe acute respiratory syndrome (SARS) in 2002~2003 and Middle East respiratory syndrome (MERS) in 2012 have accelerated our understanding of the epidemiology and pathogenesis of SARS-CoV-2 and the development of therapeutics to treat viral infection. As no specific therapeutics and vaccines are available for disease control, the epidemic of COVID-19 is posing a great threat for global public health. To provide a comprehensive summary to public health authorities and potential readers worldwide, we detail the present understanding of COVID-19 and introduce the current state of development of measures in this review.