Next Article in Journal
Study on Properties Prediction and Braiding Optimization of Axial Braided Carbon/Carbon Composite
Previous Article in Journal
Investigations on the Processing of Ceramic Filled Inks for 3D InkJet Printing
Previous Article in Special Issue
Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use
Review

Magnetic Nanomaterials as Contrast Agents for MRI

IFIMUP and Departamento de Física e Astronomia, Faculdade de Ciências Universidade do Porto, Rua do Campo Alegre 687, 4169-007 Porto, Portugal
*
Author to whom correspondence should be addressed.
Materials 2020, 13(11), 2586; https://doi.org/10.3390/ma13112586
Received: 17 April 2020 / Revised: 18 May 2020 / Accepted: 29 May 2020 / Published: 5 June 2020
Magnetic Resonance Imaging (MRI) is a powerful, noninvasive and nondestructive technique, capable of providing three-dimensional (3D) images of living organisms. The use of magnetic contrast agents has allowed clinical researchers and analysts to significantly increase the sensitivity and specificity of MRI, since these agents change the intrinsic properties of the tissues within a living organism, increasing the information present in the images. Advances in nanotechnology and materials science, as well as the research of new magnetic effects, have been the driving forces that are propelling forward the use of magnetic nanostructures as promising alternatives to commercial contrast agents used in MRI. This review discusses the principles associated with the use of contrast agents in MRI, as well as the most recent reports focused on nanostructured contrast agents. The potential applications of gadolinium- (Gd) and manganese- (Mn) based nanomaterials and iron oxide nanoparticles in this imaging technique are discussed as well, from their magnetic behavior to the commonly used materials and nanoarchitectures. Additionally, recent efforts to develop new types of contrast agents based on synthetic antiferromagnetic and high aspect ratio nanostructures are also addressed. Furthermore, the application of these materials in theragnosis, either as contrast agents and controlled drug release systems, contrast agents and thermal therapy materials or contrast agents and radiosensitizers, is also presented. View Full-Text
Keywords: nanomaterials; Gd-based contrast agents; Mn-based contrast agents; iron oxide nanoparticles; magnetic nanodiscs; synthetic antiferromagnetic nanostructures; nanowires; contrast agents; MRI; theragnosis nanomaterials; Gd-based contrast agents; Mn-based contrast agents; iron oxide nanoparticles; magnetic nanodiscs; synthetic antiferromagnetic nanostructures; nanowires; contrast agents; MRI; theragnosis
Show Figures

Figure 1

MDPI and ACS Style

Caspani, S.; Magalhães, R.; Araújo, J.P.; Sousa, C.T. Magnetic Nanomaterials as Contrast Agents for MRI. Materials 2020, 13, 2586. https://doi.org/10.3390/ma13112586

AMA Style

Caspani S, Magalhães R, Araújo JP, Sousa CT. Magnetic Nanomaterials as Contrast Agents for MRI. Materials. 2020; 13(11):2586. https://doi.org/10.3390/ma13112586

Chicago/Turabian Style

Caspani, Sofia, Ricardo Magalhães, João P. Araújo, and Célia T. Sousa. 2020. "Magnetic Nanomaterials as Contrast Agents for MRI" Materials 13, no. 11: 2586. https://doi.org/10.3390/ma13112586

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop