1. Introduction
Global climate change has emerged as one of the most pressing public health challenges of the 21st century. Global temperature trends show a consistent upward trajectory across all continents since the mid-20th century, with particularly sharp increases observed in recent decades [
1]. While earlier fluctuations were modest, the post-1980 period reflects accelerated warming, with most regions experiencing temperatures well above historical baselines [
2]. This burden has been further intensified by record-breaking temperatures reported in recent years across countries such as Algeria, Morocco, Peru, Portugal, and Spain. Heat-related morbidity and mortality remain substantial in several Asian countries, including India and Thailand. For instance, Thailand reports approximately 2500–3000 cases of heat-related illness annually, while India recorded over 31,000 heat-related deaths between 2017 and 2021 [
3,
4].
Extreme heat poses a unique health risk due to its gradual onset and lack of early signs. Prolonged exposure can overwhelm the body’s thermoregulatory mechanisms, leading to dehydration, cardiovascular strain, heat exhaustion, and heat stroke [
5,
6]. Temperature alone does not tell the whole story when it comes to heat stress; the interaction between heat and humidity is what truly drives physiological strain. Because high humidity impairs the body’s ability to cool itself through sweat evaporation, researchers rely on the heat index to accurately measure this combined thermal load. Studies consistently show that this interaction sharply increases core body temperature and cardiovascular stress, making humidity just as critical to human health outcomes as the raw air temperature [
7].
A combination of environmental, social, and demographic factors influences heat-related vulnerability. Environmental conditions amplify risk; for instance, the urban heat island effect increases temperatures in densely built areas or regions already experiencing rising temperatures. When paired with high humidity, this reduces the body’s ability to cool, thereby increasing physiological stress [
8]. Biological and demographic factors further contribute to risk, particularly among vulnerable populations. Elderly individuals, infants, pregnant women, and those with chronic diseases are at increased risk of severe outcomes. Vulnerability is also disproportionately higher among outdoor laborers, individuals of lower socioeconomic status, and populations lacking access to adequate ventilation and cooling systems [
9]. Social factors play a critical role, as housing quality, access to ventilation, occupational exposure, and healthcare access significantly shape health outcomes [
10]. Overall, environmental exposures, coupled with social determinants such as housing conditions, healthcare access, and occupational risk, amplify susceptibility to heat-related illnesses [
11].
India has long been recognized as one of the global hotspots for heat-related morbidity and mortality, with rising temperatures contributing to a substantial and growing public health burden. Evidence suggests that heat-related mortality among older adults has increased by nearly 68% over the past two decades, with Asia accounting for a significant proportion of global heat-related deaths [
12,
13]. Across major cities in India, widespread exposure, high population density, and underlying vulnerabilities have resulted in large segments of the population being at high to very high risk of heat-related illness. Clinically, heat-related illness in the Indian context often presents with severe complications, including multi-organ dysfunction and significant mortality, highlighting the severity of the burden [
14]. At the same time, sustained exposure to this burden has pushed India to move toward active heat adaptation. Interventions such as heat action plans, early warning systems, and community-based strategies have been introduced to improve preparedness and reduce risk [
15,
16]. While gaps in implementation remain, these efforts offer a strong, real-world framework for how health systems can respond to extreme heat.
Unlike major cities in India, South Florida represents an emerging risk environment where rapid warming is not yet matched by equally developed public health response systems. The region’s high humidity, aging population, and urban heat island effect contribute to increased physiological stress and heat-related illness [
17,
18]. While healthcare infrastructure is more developed and readily available, disparities persist; limited access for lower-income families continues to drive vulnerability. Research has demonstrated an increasing rate of heat-related hospitalizations across South Florida, highlighting a growing burden of extreme heat in subtropical urban environments [
5]. Moreover, rising surface temperatures due to greenhouse gas emissions have increased the frequency and severity of extreme heat events worldwide [
19]. These environmental changes are associated with substantial increases in heat-related mortality and morbidity.
Major cities in India and South Florida share a comparative framework: both regions experience high temperatures, but they differ in infrastructure, socioeconomic conditions, and healthcare access. India is one of the world’s hotspots for heat-related mortality and morbidity, characterized by consistently high baseline temperatures and extreme heat waves. It also faces heatwaves that affect large populations, particularly working people and aging populations [
20]. In contrast, South Florida, while buffered by coastal influences, is experiencing a rapid acceleration of the warming trend. Even though South Florida has more developed healthcare systems and greater clinical capacity than India, it faces compounding risks from high ambient humidity, rapid urbanization, an aging population, and a large outdoor workforce [
17,
21].
Despite increasing concern around rising temperatures, there remains limited research specifically examining how long-term heat trends translate into measurable health outcomes in South Florida. Heat-related hospitalizations serve as a critical and observable indicator of population-level burden, as they capture severe manifestations of heat exposure that require clinical care and reflect strain on the healthcare system [
11]. While existing studies have documented rising temperatures and general health risks, there is a lack of integrated analysis linking these trends to hospitalization patterns at a regional level. This gap is particularly important in South Florida, where rapid warming, high humidity, and underlying population vulnerabilities intersect, yet the extent to which these conditions are already translating into increased healthcare burden remains underexplored.
In contrast, major cities in India have already experienced a sustained and severe burden of heat-related illness, providing an important reference point for understanding how South Florida might compare as temperatures continue to rise [
13]. For example, a prehospital surveillance study in Telangana, India, recorded a heat illness incidence of 1.5 cases per 100,000 population during the 2018–2019 heat wave seasons, rising to 4.5 per 100,000 among rural and tribal populations [
22], and a comprehensive multi-city analysis estimated approximately 1116 heatwave-attributable deaths per year across ten major Indian cities, including three of the cities examined here: Delhi, Chennai, and Mumbai [
13]. Climatically, this comparison is grounded in a shared thermodynamic burden where both regions experience humid subtropical conditions, i.e., persistent-near-saturation humidity compounded by high temperatures [
23,
24]. This humidity-heat interaction severely impairs sweat evaporation, creating identical physiological strain and thermal risk profiles for outdoor populations in both settings. These patterns provide a benchmark for understanding where South Florida stands relative to a high-burden setting. Moreover, given India’s long-standing experience with heat-related illness, it serves as a critical reference case from which actionable lessons can be drawn to inform early and proactive public health responses in emerging high-risk regions. The purpose of this comparison is not to establish direct socioeconomic equivalence, but to anchor South Florida, an emerging humid subtropical risk zone, against a benchmark region with long-standing exposure to extreme heat-humidity interactions. By comparing a rapidly warming coastal context with an established high-burden setting, this framework highlights how severe physiological stress operates across different infrastructural landscapes. Although geographic and seasonal variability exist, including winter temperature differences and considerable climatic heterogeneity within India, baseline heat exposure remains consistently elevated in both settings [
20]. Importantly, India also serves as a reference model for large-scale heat adaptation, having implemented interventions such as heat action plans, early warning systems, and community-based response strategies that have demonstrated measurable reductions in heat-related mortality. This comparison is intended as a conceptual benchmarking approach rather than a direct pooled statistical analysis, given differences in data availability, structure, and context across the two regions.
This study examines how rising temperature trends in South Florida compare to those observed in India, evaluates how these trends are associated with heat-related hospitalizations in South Florida, and explores how insights from India can inform early public health adaptation strategies. The comparison with India is intentional, as it represents a high-burden setting that has already experienced sustained heat-related health impacts and has begun implementing adaptation strategies. While prior research has largely examined temperature trends or heat-related health outcomes separately, there remains limited work that directly links long-term climate patterns to real-world healthcare burden in emerging subtropical regions such as South Florida, or that uses high-burden global settings to inform early response strategies. This study addresses that gap by integrating temperature trends with hospitalization data in South Florida, while using India as a reference case to better understand risk patterns and identify practical, early-stage public health responses to rising heat exposure.
3. Results
This section presents the observed temperature trends, temporal patterns in heat-related hospitalizations, statistical associations between temperature and hospitalization rates, and a cross-regional comparison of warming trajectories.
Table 1 summarizes the temperature records and heat-related hospitalization data included in the study. The analysis included seven South Florida weather stations spanning 1912–2025 and five Indian cities spanning 1951–2024, although the 2024 Indian observations represent only a partial calendar year. Mean annual temperatures varied across locations, with greater cross-location temperature variability among the Indian cities than among the South Florida stations. Both regions demonstrated positive long-term warming trends, with the mean station-level rate estimated at +0.0253 °F per year in South Florida and +0.0230 °F per year in India. Descriptive Characteristics of Temperature Records, Warming Trends, and Heat-Related Hospitalizations in South Florida and India are shown in
Table 1,
Table 2,
Table 3,
Table 4 and
Table 5.
Between 2005 and 2023, the three South Florida counties recorded 2653 heat-related hospitalizations. Broward reported the highest total number of hospitalizations, while Palm Beach had the highest mean age-adjusted hospitalization rate. South Florida’s summer mean temperature increased from 83.87 °F in 2005 to 85.02 °F in 2023, although the estimated linear trend was not statistically significant. These findings provide a descriptive overview of the temperature and hospitalization patterns examined in the study.
3.1. Temperature Trends
Both South Florida and India exhibited clear and sustained upward temperature trends over the study period, as illustrated in
Figure 1A–D.
Figure 1A illustrates long-term annual mean temperature patterns across seven South Florida weather stations. Although the stations differ in record length and year-to-year variability, most show an upward temperature trajectory over their available observation periods. The strongest warming trends are visible in Hialeah and Miami Airport, while Everglades shows a comparatively modest increase. Miami displays greater annual variability and several pronounced temperature departures, whereas Fort Lauderdale, Key West, and West Palm Beach follow steadier upward patterns. Taken together, these station-level records indicate that warming has occurred across much of South Florida, although its magnitude and consistency vary by location.
Figure 1B presents long-term annual mean temperature patterns for Bengaluru, Chennai, Delhi, Kolkata, and Mumbai. All five cities show positive warming trajectories across their available records, although the pace and year-to-year variability differ by location. Mumbai and Chennai exhibit the strongest estimated warming rates, while Delhi shows a more gradual long-term increase. Bengaluru and Kolkata also demonstrate sustained upward patterns despite periodic annual fluctuations. The pronounced increases at the end of several series should be interpreted cautiously within the broader historical record. Overall, the city-level findings describe a broadly consistent pattern of warming across geographically and climatically diverse areas of India.
Figure 1C compares the regional annual mean temperature trends for South Florida and India. Both regions exhibit sustained upward trajectories over their respective observation periods. South Florida warmed at approximately +0.0265 °F per year, compared with approximately +0.0230 °F per year in India, a difference of about 0.0035 °F per year. South Florida’s record shows substantial year-to-year fluctuation, particularly during the earlier portion of the series, while India’s regional average follows a somewhat more stable upward path before a pronounced increase in the latest observation. Despite these differences in variability and record length, the descriptive trends show that both regions experienced long-term warming, with South Florida displaying a slightly higher estimated annual rate.
Figure 1D compares the estimated annual warming rates for each South Florida station and Indian city. All included locations show positive warming rates, but the magnitude of warming varies considerably. Hialeah and Miami Airport display the highest estimated rates, at approximately +0.0495 °F and +0.0454 °F per year, respectively. Among the Indian cities, Mumbai shows the highest rate at approximately +0.0319 °F per year, followed by Chennai at +0.0283 °F per year. Everglades and Delhi exhibit the lowest estimated rates within their respective regions. These findings highlight the geographic variability underlying the broader regional trends: warming is evident across the included locations, but it has not occurred at the same pace everywhere. Because the station records cover different observation periods, the rates should be viewed as descriptive summaries of each location’s available record rather than strictly equivalent comparisons.
3.2. Temporal Trends in Heat and Hospitalizations in South Florida
South Florida has shown a steady increase in temperature, with warming accelerating in recent years as show in
Figure 2. India showed a similar upward trend, though with greater year-to-year variability attributable to monsoon seasonality and regional climate diversity. Critically, heat-related hospitalization rates in South Florida rose in parallel with this warming signal, indicating that temperature increases are already occurring alongside a rise in measurable healthcare burden. The regression analysis confirmed statistically significant positive association trends in both temperature and hospitalization outcomes across the study period, showing a consistent temporal association between rising ambient temperatures and increased heat-related health events.
3.3. Association Between Temperature and Hospitalizations
Table 2 summarizes the association between summer mean temperatures and age-adjusted heat-related hospitalization rates across South Florida. These findings are exploratory and should not be interpreted as causal or predictive. All three counties demonstrated statistically significant positive relationships between temperature and hospitalization rates, accompanying a measurable increase in heat-related healthcare demand. Miami-Dade County showed the strongest model fit (R
2 = 0.615,
p < 0.001), meaning that summer mean temperature alone accounts for approximately 62% of the variation in age-adjusted hospitalization rates, a substantial explanatory share for a single predictor in an ecological model. The regression equation for Miami-Dade (Hospitalization Rate = −65.0 + 0.80 × T) implies that for each 1 °F increase in mean summer temperature, hospitalization rates rise by approximately 0.80 cases per 100,000 population. Broward County showed a similarly strong association (R
2 = 0.573,
p < 0.001), with a slightly steeper slope (1.03 per °F), suggesting that each degree of warming in Broward corresponds to roughly one additional hospitalization per 100,000 residents. Palm Beach County showed a weaker model fit (R
2 = 0.356,
p = 0.007), indicating greater variability in hospitalization rates that temperature alone does not fully explain, possibly reflecting differences in population age distribution, access to cooling infrastructure, or local reporting patterns. Nevertheless, the relationship remains statistically significant, reinforcing the regional pattern. The combined model across all counties (R
2 = 0.373,
p < 0.001) confirms a consistent positive association at the regional level. Associations between Summer Temperature and Heat-Related Hospitalizations in South Florida (2005 to 2023) are depicted across
Table 6,
Table 7 and
Table 8.
Summer mean temperature was positively associated with age-adjusted heat-related hospitalization rates across all three South Florida counties (
Table 6,
Table 7 and
Table 8). The direction of the association remained consistent whether it was measured using Pearson correlation or the rank-based Spearman correlation. The county-specific Pearson correlations ranged from 0.597 in Palm Beach County to 0.784 in Miami-Dade County, and all three associations were statistically significant.
Miami-Dade showed the strongest linear model fit, with summer mean temperature accounting for approximately 62% of the observed variation in its annual age-adjusted hospitalization rate (R2 = 0.615). Each 1 °F difference in summer mean temperature was associated with an estimated difference of 0.80 hospitalizations per 100,000 population (95% CI: 0.48–1.12). Broward showed a similarly strong pattern (R2 = 0.573), with an estimated difference of 1.03 hospitalizations per 100,000 for each 1 °F difference in temperature (95% CI: 0.58–1.48).
The association in Palm Beach was more variable but remained positive and statistically significant. Each 1 °F difference in summer mean temperature was associated with an estimated difference of 1.08 hospitalizations per 100,000 (95% CI: 0.34–1.82), and the model accounted for approximately 36% of the observed variation in annual rates (R2 = 0.356). The wider confidence interval reflects greater uncertainty around the Palm Beach estimate.
When observations from all three counties were combined, the model showed a moderate positive association (r = 0.568, R2 = 0.323, p < 0.0001). The pooled coefficient indicated an estimated difference of 0.97 hospitalizations per 100,000 for each 1 °F difference in summer mean temperature (95% CI: 0.59–1.35). However, this estimate should be interpreted cautiously because the same annual regional temperature was assigned to all three counties, and the pooled model’s residuals did not satisfy the normality test. Moreover, the small sample size (N = 19 per county) makes R2 and p-values less stable.
Figure 3 makes these patterns easier to see. The county-specific panels show positive fitted slopes in Broward, Miami-Dade, and Palm Beach, while also showing the annual variation around each regression line. Together,
Table 6,
Table 7 and
Table 8 and
Figure 3 describe a consistent positive association between warmer summers and higher heat-related hospitalization rates during 2005–2023. These findings remain exploratory and do not establish that temperature alone caused the observed changes in hospitalizations, particularly given limited access to granular data and the absence of key variables that may confound or modify this relationship.