Small/Kiddie Cigarette Packaging Size and Its Impact on Smoking: A Systematic Review

Abstract Background: Small cigarette pack sizes contain less than 20 cigarette sticks in a pack. Smaller packs may suggest lower costs, increasing affordability among lower-income users, especially the younger generation, which could lead to tobacco-related diseases and economic costs, including human capital lost results from tobacco-attributable morbidity and mortality. This concern has caused many countries to ban the sale of single cigarette sticks or kiddie packs. However, small cigarette pack sizes were proposed recently to be reintroduced by the tobacco industry with an excuse to prevent consumers from buying illicit cigarettes. This would demean efforts in combating tobacco consumption based on the existing tobacco control policies to prevent minors from purchasing cigarettes. Given the competing influences of affordability and availability of tobacco on consumption and the dearth of evidence-based review on the impact of pack size on smoking, this systematic review was conducted to identify the link between kiddie packs and smoking specifically on the initiation of smoking, urge/tendency to buy cigarettes among the general population and attempt to reduce cigarette consumption and prevalence of smoking using kiddie packs among current smokers. Methods: We include all studies except for reviews, guidelines, conference papers, commentaries, editorials, or opinion pieces. A database search was conducted in PubMed, EMBASE, CENTRAL, Web of Science and Scopus on 27 November 2021. The results were presented in the form of narrative synthesis under four groups: initiation of smoking; urge/tendency to buy cigarettes; the prevalence of smoking, and attempt to reduce cigarette consumption. The literature search identified 1601 articles, of which 21 articles had met the inclusion criteria. The methodological quality of all included articles was determined using a validated 16-item quality assessment tool (QATSDD). The average quality score for all papers was 34.8%. Discussion: Given the diverse study settings of the articles and despite the challenges of the methodological quality of some articles, this review provides some evidence that kiddie packs may increase the urge/tendency to buy cigarettes and mixed evidence on the attempt to reduce cigarette consumption. This review also found some evidence that kiddie pack purchasing among teenage smokers was higher compared to adults. However, we are uncertain about the link between kiddie packs and smoking initiation. Nevertheless, since most studies were of low quality, further high-quality studies are needed to conclude about the impact of kiddie packs on smoking to assist the policymakers and stakeholders in formulating new policies and strengthening existing strategies related to the kiddie packs.


Introduction
In the year 2015, over 1.1 billion people smoked tobacco globally. About six million people per year die (prematurely) due to tobacco use (smoked and smokeless), according to the World Health Organisation [1]. Smoked tobacco includes manufactured cigarettes, Two reviews were found to publish on the effects of tobacco package quantity on consumption. The first review found articles concerned about the cigarette length [25], and the latter discussed the tobacco companies' rationale for introducing or changing package amount and packaging type in an effort to influence consumer behaviour; the search was limited to Truth Tobacco Industry Materials (TTIDs) documents [26].

Evidence Gap
Given the dearth of published information on the direct influence of cigarette pack size is currently uncertain, an evidence-based review of the impact of kiddie cigarette packs on smoking is needed to provide reliable evidence to assist policymakers and stakeholders in formulating new policies and strengthen existing strategies related to the kiddie packs. This would reduce the burden of the government on the health care cost associated with treating diseases caused by tobacco and the human capital lost due to tobacco-attributable mortality and mortality in the future [4]. To our knowledge, no published systematic review addresses our questions, (1) What is the link between kiddie packs on initiation of smoking in the general population? (2) What is the link between kiddie packs on the urge/tendency to buy cigarettes in the general population? (3) What is the link between kiddie packs and an attempt to reduce cigarette consumption among current smokers? (4) What is the prevalence of smoking kiddie packs among current smokers? Therefore, this review was conducted to identify the link between kiddie packs with initiation of smoking, urge/tendency to buy cigarettes in the general population, attempt to reduce cigarette consumption and the prevalence of smoking kiddie packs among current smokers.

Research Objective
This review aims to identify the link between kiddie packs and smoking. The objectives are:

1.
To identify the link between kiddie packs specifically on the initiation of smoking, urge/tendency to buy cigarettes in the general population 2.
To identify the link between kiddie packs and attempt to reduce cigarette consumption among current smokers 3.
To determine the prevalence of smoking using kiddie packs among current smokers We conducted a systematic review based on our published protocol [27]. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines in conducting and reporting the results of this systematic review (Supplementary  Materials Table S1).

Eligibility Criteria
We planned to include all randomized controlled trial, quasi-experimental and experimental studies observational cross-sectional, case-control and cohort studies in this review. We used PECO acronym where P is population specifically any individual with the attempt for initiation of smoking or the urge/tendency to buy kiddie packs in the general population, E is exposure which were those who buy/consume kiddie packs, C is comparators for the impact of kiddie packs was compared with regular sized cigarette packs and O is outcomes which are those mentioned in the objectives above.

Study Design
In this review, we only found three cross-sectional studies for inclusion in this review [18,21,28]. Hence, we made a post-hoc decision to include other types of observational studies, namely qualitative analysis and hypothetical modelling, that addressed the same kind of intervention and outcome. We included original articles in this review without restriction on the publication dates. We included the population-based studies that had cigarettes available for consumption/sale in small cigarette pack sizes compared to standard/larger packs.

Search Strategy
We searched electronic databases to identify all published studies that could be considered eligible for inclusion in this review. We hand searched unpublished studies for inclusion in this review. We used terms such as "cigarette" and "mini pack" OR "kiddie packs" OR "small packs" and "Smoking initiation" OR "impulse to buy" OR "urge to buy" OR "tendency to buy" OR "smoking reduction" as a basis for keyword search. A detailed keyword search is depicted in Table S2 (Supplementary Materials). The literature search identified potential studies in all languages. We searched five databases, including PubMed, EMBASE, The Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science and Scopus, on 27 November 2021. The snowball sampling technique was used to find related studies from the references section of the studies found. The reference from the systematic review or scoping reviews pertaining to the effects of cigarette package size on consumption was also performed.
We retrieved and reviewed all full texts of potentially relevant articles if the title or first few pages contained information about research on kiddie packs, small cigarette packs, pack size or factors that influence smoking initiation, smoking consumption, or urges/tendencies to buy cigarettes, with regards to kiddie packs.

Study Selection
Initial search revealed, a total of 1959 potential papers where 1601 articles were obtained after removing duplicates. . After the titles and abstracts screening, 20 full-text articles were retrieved, and 18 additional articles were identified via cross references. Three pairs of reviewers independently reviewed the full text of these additional articles. Any disagreements were resolved through discussion or referred to the ninth author as a referee (N.A.M.). Of these, twenty-one articles met the inclusion criteria for this review. A detailed description of the process is described in Figure 1.

Data Extraction
Data extraction and analysis were carried out independently by two pairs of reviewers (H.M.R. & M.Y.J.L., T.A. & T.G.R.L.). Another two pairs of review authors independently extracted data using a standardized data extraction form containing information about the authors, year of publication, place of study, study design, number of respondents, type of packaging, outcome and the 16-item quality assessment tool (QATSDD) score (Table 1) Themes were prespecified a priori categories from the previous research but were adapted on the basis of the information reported in the included studies [29]. Data were thematically analysed on the link between kiddie packs on initiation of smoking, urge/tendency to buy cigarettes, the prevalence of smoking (using kiddie packs), and attempts to reduce cigarette consumption.  -Reduce cigarette consumption -Urgency/tendency to buy cigarettes (price affordability, convenience to carry, attractive appearance) Sponsored by a tobacco company • beneficial to those with the least money (youth, beginner smokers, the poor) and was frequently referred to as the 'poverty pack', with people admitting to having purchased 15's with a self-conscious and self-deprecating laugh.
-Attempt to reduce cigarette consumption • associated with those attempting to quit smoking through gradually cutting down.
-for those who may desire an occasional change in brand.

24%
Sponsored by a tobacco company • most respondents said that the 10-pack appeared to be more bargain than the current pack. • it is the potential to be viewed as a trial size that one would purchase to try a new brand.
Response for 15 cigarettes: -Attempt to reduce cigarette consumption (to cut down on smoking) -consider 15 cigarettes as too small for those who smoke more than 15 cigarettes per day 29% Sponsored by a tobacco company Cox AR. (1983) [43] Qualitative study N/A Detroit and Tanpa -at the retail outlet only.

packs
In the USA -12's pack did not generate much purchase.
-Useful for temporary promotional purposes to generate occasional trials. -smokers who are interested in cutting down/occasional light smokers, smokers who have not been smoking for a great deal of time would be interested in 12 packs -79% of the smokers probably and would not probably buy 12 pack -Over half of the buyers said they would probably or definitely repurchase a 12-pack. -Skewed towards young adults(mean) and lower-income smokers. -Some of the reasons for buying 12 pack are:

•
Urge/tendency to buy cigarettes (small size, price affordability)

Assessing the Study Methodological Quality and Bias
The included studies are diversed in terms of study designs, data collection methods, data types, and analytical methods used. Due to this, we decided to use QATSDD compared to ROBINS-I and Rob2 as stated as options for risk of bias of assessment in our protocol. It is a validated tool developed by Sirriyeh et al. [47], and it was used by other studies such as Vyth et al. [48], Hughes et al. [49] and Adam & Jensen [50].
The tool consists of 16 criteria (14 of these criteria apply to qualitative studies, 14 apply to quantitative studies, and all 16 apply to any mixed methods papers), each with a score ranging between 0 and 3, with three being the best. The maximum score for mixed papers is 48 and 42 for qualitative or quantitative. Aspects of clarity were reflected in the description of aims and setting, data quality, method of analysis and self-evaluation. Two independent pairs of reviewers assessed the fulfillment of 16 criteria for each publication based on the information provided in the full assessed texts and a score corresponding to the level of satisfactory attainment of the criteria outlined by QATSDD tools.
The scores were added and divided for each full text by the maximum possible score to report the paper's overall quality score. A score of 0 was given if the authors had not included the level of detail required to make a judgement for quality criteria.
The first pair of reviewers assessed all studies, and inter-rater reliability was determined by rating a random selection of the second pair of reviewers and the third pair of reviewers. Disagreements were resolved through discussion and abstract screening. Quality of papers was used to guide the review in terms of implications of each study and to inform the conclusion made from outcomes. Study quality was categorised based on the GRADE approach [51]. Scores of 0-25% were considered very low quality; 26-50% low quality; 51-75% moderate and scores of 76-100% were considered of high quality [51]. A direct comparison of study quality could be done based on this category and a consistent interpretation of QATSDD could be promaded. Lower-quality studies are more likely to have systematic errors or higher levels of bias [51].

Results
A formal meta-analysis was not possible due to the heterogeneous nature of study settings, designs and outcome measures. Therefore, studies with a similarly themed component were grouped for narrative synthesis. Data were grouped based on the link between kiddie packs with initiation of smoking, urge/tendency to buy cigarettes, and attempt to reduce cigarette consumption among the population.

Summary of the Main Results of the Included Studies
While searching relevant papers for inclusion in the review, a total of 1601 potential papers were identified after duplications were removed. After the titles and abstracts screening, 38 papers were selected for further screening. Of those, we included 21 studies. Of the 21 studies, 4 studies were conducted independently whereas the remaining 17 studies were conducted by the tobacco companies.
Summary of findings containing information on study type, data collection and analysis and methodological quality were presented in Table 1.

Methodological Quality and Bias of Included Studies
Scoring for study quality was based on the QATSDD's 16 criteria and a summary of each study has been included below.
The methodological quality scores of all the included studies range between 14% to 74%, yielding an average quality score of 34.8%. The methodological quality of four studies which were conducted independently [18,21,30,31] ranged from 50% to 74%, with one [21] being low quality and others being moderate in quality [18,30,31]. Meanwhile, the articles conducted by the tobacco industry company ranged from 14% to 55%. Only 1 article was moderate in quality [30] and others were either of poor or very poor quality.
Based on the GRADE approach category, 4 studies were categorised under moderate studies [18,30,31,38] and the majority (11 studies) were under low-quality studies. The quality assessment revealed that research on the topic largely failed to report the rationale for assessment of the reliability of the analytic process (Criteria 14), evidence of user's involvement in design (Criteria 15), detailed recruitment data (criteria 8), good justification for the analytical method selected (Criteria 13), fit between stated research question and method of data collection (Criteria 11), fit between research question and method of analysis (Criteria 12), representative sample of a target group of a reasonable size (Criteria 5) and Statistical assessment of reliability and validity of measurement tools (Criteria 9) to allow for research to be replicated. Of those studies with scores higher than 50%, 3 [21,30,31] were independent of the tobacco company and 1 was sponsored by the tobacco company [38]. Criteria for which most studies scored low include assessment of the reliability of the analytic process (0.0%), evidence of user's involvement in design (1.6%), and recruitment data (12.7%). These scores were low due to the inadequate level of detail included by the authors for the paper included. Table 2 shows the mean and standard deviation of the 16 methodological assessment criteria. Almost all evaluated studies scored an average mean of 2.81 for a "clear description of research setting". The lowest average scores were found for "assessment of the reliability of analytic process" and "evidence of user involvement in design"; the average scores were 0.00 and 0.05 respectively. The details of the critical appraisal of the included studies are shown in Table S3 (Supplementary Materials).

Study Design and Setting
The studies were different in terms of study type, sample size and target population. Studies were conducted in the United States of America (USA), Australia, United Kingdom (UK), Ireland Canada, Puerto Rico and Paraguay. Sixteen were qualitative studies [32][33][34][35][36][37][38][39][40][41][42][43][44][45][46], three were cross-sectional studies [18,21,28], one was computer based online survey [30], and one was modelling count data process study [31]. The qualitative studies generally did not provide significant tests or impact sizes. Fourteen studies used sample packs [21,28,32,33,[36][37][38][39][40][41][43][44][45][46] but the other six used product images [30,31,34,35,37,42]. Only 6 studies detected the link between the kiddie packs and smoking after their introduction into the market [18,21,28,38,45,46]. From these 6 studies, most concluded that the urge to buy cigarettes is the effect of the kiddie cigarette pack in the market. Of those, only 2 studies investigated the link between kiddie packs on teenagers [18,21]. The study reported that more than half the adolescent smokers (age 14 and 15) (56.3%) had purchased a packet of 15 cigarettes in the month prior to the survey compared to adult smokers (8.8%) [21], which revealed that kiddie packs attracted more teenage smoker consumers compared to adults. The study also found that the majority of the consumer gave the price as the reason to purchase a packet of 15's [21]. The other fifteen studies were designed to detect the potential impact of kiddie packs on smoking.

Participants
The included studies with complete age and sample size information revealed that the participants' age range from 12 to 54 years old, whereas the sample size ranged from 6 to 5766 participants.
Of the 4 independent articles of the tobacco company, 3 articles conducted studies among adolescents [21,31] and children [18] and others were conducted among adults [30,31]. For tobacco industry company-sponsored study, most of the studies that had complete age information were conducted among adults.

Issues of Quality and Bias in the Included Studies
Wilson et al. [21] used a convenience sample from high schools in Adelaide, Australia. This study focused on adolescents aged 14 and 15 only and limited its survey to only two brands of cigarettes presenting a potential selection bias of the sample; a wider range of age and brands may have provided further insight. The authors justified their choice of study designs with clear methods but there was no discussion around potential confounders for their results.
A study in Ireland used stratified random sampling from 8+ years of living in the Republic of Ireland. The survey did not limit its survey to a specific brand. The authors justified their choice of study design with a clear method but no discussion around potential confounders for their results [18].
Marti & Sindelar (2015) [30] used a computer-based online survey, which involved the recruitment of adults who were smokers and registered to the Yale School of Management Lab, which acted as a platform for online surveys and experiments. This led to a potential selection bias in the sample. They provided the justification for the study design and clear methods and there was discussion around potential confounders for their results.
Farrell, Fry & Harrus (2010) [31] used secondary data from an individually based nationally representative survey involving adults between the ages of 16 to 74 years old living in England. They provided relevant details and used an appropriate approach according to the objectives of their study. Potential confounders from the results were extensively discussed.
Gomez & Guevara (1993) [28] interviewed respondents in Puerto Rico on smoker's consumer behaviours. Multiple cigarette brands were included in the study for the diversity of the consumers, but no other detailed sampling methods or study designs were explained. Potential confounders were also not discussed leading to potential bias.
Burke Marketing Research in its Package Size Evaluation Study (1983) [39] explored the possibilities of marketing cigarettes in a new package size. The study design and sample size was poorly described. Convenient sampling was applied within selected shopping malls during the malls' operating hours. Respondents' selection criteria were not mentioned. 5.6. Outcome of the Included Studies 5.6.1. Urge/Tendency to Buy Cigarettes Kiddie packs increased the urge to buy cigarettes among smokers which were consistent with several studies discussed below. There were several reasons that influenced the urge to buy cigarettes in kiddie packs.

Convenient to Carry
Another eleven studies revealed that the urge to buy kiddie packs was due to the convenience of carrying them around [30,[33][34][35][36][37][38][39]44,46]. A focused group study done by a research company named Paul A. Warner Association [37] showed that kiddie packs are more convenient to carry in a pocket or small purse when going to a club/party. A small qualitative study conducted by another research company which was funded by a tobacco company noted that kiddie packs were good for evening use as they fitted better into an evening bag and the quantity was sufficient for smoking after dinner [39].

Small Size
Nine studies revealed the reason for buying kiddie packs was due to their small size [32][33][34]37,39,40,[43][44][45]. Women smokers were motivated to purchase kiddie packs as it was seen as more discreet and cuter [33]. Another reason was that the smokers just wanted to try a new product that had a lesser number of cigarettes. Studies [43,45] found that kiddie packs were seen as something new that influenced people to try.

Attractive Appearance
Six other studies also found that the urge to buy kiddie packs increased because they were more attractive and stylish [32,[34][35][36]40,45].

Concealment
Two studies found that the reason for buying kiddie packs was because it was easy to hide. Causey in a qualitative study in Paraguay found that the reason younger smokers bought kiddie packs was due to its ease in being concealed as they were not supposed to be smoking [46]. This was similar to a finding by Wilson et al. [21] which noted that concealment was among the reasons adolescents aged 14 to 15 years old in Adelaide bought kiddie packs.

Attempt to Reduce Cigarette Consumption
We found mixed findings on this outcome. Attempt to reduce cigarette consumption/ smoking cessation were among the main reasons for buying kiddie packs. Some of the current smokers preferred kiddie packs as a tool to quit smoking and reduce or maintain a desired consumption level. There were ten twelve studies that discussed attempts to re-duce cigarette consumption [28,30,[34][35][36][37][38][39]41,42,46].
Marti & Sindelar (2015) [30] noted that smokers who preferred smaller cigarette packs were more likely to want to quit smoking and more than 70% of smokers purchased kiddie packs to limit their cigarette consumption. Farrel, Fry & Harrus (2011) [31] hypothe-sized that smokers regulated their consumption according to the size of packs that were available. That study also stated that the average number of cigarettes smoked by a typical smoker was 10 sticks per day, which was equivalent to the number of sticks in the smallest packs that consumers can purchase in England. The other nine studies also showed that one of the reasons for kiddie pack preference was to smoke lesser with a smaller pack size. However, there was a study in Ireland that found that consumers prefer to continue buying kiddie packs if there was no increase in price and the majority had no intention to quit smoking [18].

Prevalence of Smoking (Using Kiddie Packs)
We found a study which that reported that more than half the adolescent smokers (age 14 and 15) (56.3%) had purchased a packet of 15 cigarettes in the month prior to the survey, which was higher compared to adult smokers (8.8%) [21]. Another study in Ire-land also revealed that the majority (80%) of adolescent smokers aged 12 to 17 more often purchased kiddie packs (pack of 10 vs. 20 packs) compared to adults (24%) [18]. Both findings revealed that kiddie packs attracted more teenage smoker consumers compare to adults.

Initiation of Smoking among Population
We did not find any study that discussed the link between kiddie packs and smoking initiation.

Discussion
We utilised a methodological assessment instrument to evaluate both quantitative and qualitative studies on the relationship between child cigarette packaging and smoking in an objective manner. It is likely that the ratings will be underestimated when research meet the criteria listed in the evaluation tool without clear reporting in the publication. The evaluation revealed that the majority of the research were of poor quality.
This research identified just a small number of studies on the actual link between kiddie packs and smoking. Based on our review, it answers our first objective of identifying the link between kiddie packs and the urge/tendency to buy cigarettes. The majority of included studies found that kiddie packs were purchased because to their lower price, which increased the purchase of cigarettes among smokers. The cheaper prices of cigarette packs encouraged smokers, particularly youths and those with limited incomes, to purchase smaller packs [18,21]. This is consistent with research indicating that lower prices can encourage/attract low-income consumers, primarily adolescents and minors, to purchase kiddie/smaller cigarette packs due to their affordability [53], as it has also been demonstrated that tobacco consumption increased when prices decreased [11,12]. In addition, this study corroborated the present tobacco policies of many nations, which restrict minimum cigarette packet numbers to enhance barriers to use by youngsters [26]. This indirectly discourages adolescent smoking, as smoking has numerous negative impacts on the body. There were two (independently non-funded by the tobacco industry) post-marketing crosssectional studies focused on the link between kiddie packs and smoking [18,21]. Based on our study, 2 studies demonstrated that young smokers under the age of 18 had a greater propensity to purchase kiddie packs than adults. Wilson et al. [21] conducted a study in the metropolitan area of Adelaide to explore current smoking behaviour (in terms of the desire to purchase) and evaluate new cigarette marketing strategies among 14-to 15-year-old adolescents, in which two prominent brands were supplied in 15-count packets. Compared to adult smokers (8.2%), more than half of adolescent smokers (ages 14 and 15) had purchased a pack of 15 cigarettes in the month before to the poll, according to their research. The primary reason was its reasonable price. Another study indicated that the majority of adolescent smokers between the ages of 12 and 17 (80%) were more likely to purchase kiddie packs (10 packs vs. 20 packs) than adults (24%). The majority of adult smokers began smoking as adolescents [17]. %According to a 2016 survey of 143 adolescent smokers, 70% began smoking between the ages of 12 and 15. Nearly 60% did not even enjoy smoking and unsuccessfully attempted to quit. Another survey of people aged 8 and older in Ireland found that 78% of smokers began before the age of 18 and 53% before the age of 15. This demonstrated that smoking initiation mostly affects children and adolescents [18]. This is particularly concerning because smokers exposed themselves to the negative effects of cigarettes at a very young age, which led to smoking-related ailments [17] and other highrisk behaviours [54]. The economic cost of tobacco is substantial and includes astronomical health care expenses for treating diseases caused by tobacco use. In addition, human capital is lost as a result of tobacco-related disease and mortality [4].
In addition to kiddie packs' affordable pricing, the desire to purchase them was fueled by their portability and concealability, particularly among women and younger smokers due to their diminutive size [21,33,46,52]. As stated in the preceding paragraph, since the majority of kiddie pack consumers were adolescents, the concealment of kiddie packs from their parents would allow the adolescents to continue smoking as their parents would be unaware of their smoking status. Multiple studies have demonstrated that parental participation is an important protective factor against daily smoking among teenagers [54]. In addition to the engagement of other parties, such as school-based intervention [55], high parental involvement significantly reduced the likelihood of adolescents becoming current smokers [54]. In addition to the tobacco-related disorders that might result from smoking, high-risk behaviour can be a consequence of tobacco use [4]. Studies have found a substantial correlation between alcohol consumption and cigarette smoking [54]. Multiple theories led to the link between alcohol consumption and smoking [54]. The interaction between the role of peer influence, subculture theory, psychological discomfort, and sociocultural influence may account for the concurrent use of cigarettes and alcohol. In addition, studies have demonstrated a correlation between smoking and school absenteeism [54]. Several research have shown contradictory results about this association. Absenteeism may be caused by smoking-related sickness or delinquent behaviour that leads to smoking. In addition, research indicates that smoking is connected with bullying [54]. On the basis of these arguments, it is vital to discourage adolescents from smoking at a young age, as smoking is associated with numerous negative health effects and high-risk behaviour. Current tobacco policies deter adolescents from smoking by limiting their ability to ob-tain cigarettes and imposing a high cost on tobacco products. The desire to purchase kiddie packs was also influenced by their appealing appearance. Tobacco control efforts in a number of nations include the sale of plain packaging to deter consumers from being attracted to the appearance of cigarette packs. As resources are extremely limited, however, additional high-quality research examining the influence of kiddie packs on the desire to buy cigarettes are required.
This evaluation also uncovered contradictory evidence for the second objective: link between kiddie packs and attempts to reduce cigarette smoking among current smokers, although additional high-quality research is required to verify this. Literature indicates a correlation between cigarette pack size and the number of cigarettes smoked [10]. Daily self-reported smoking was positively correlated with pack size [10]. Certain smokers utilise small packs as a way for regulating their cigarette consumption [10]. Our analysis revealed that one of the motivations for purchasing kiddie packs was to limit cigarette usage. Based on the regression models, Marti and Sindelar (2015) [41] found that pack size preferences corresponded to current cigarette use, so smokers who wished to quit and those with a stronger degree of self-control tended to purchase small packs. Wilson et al. (1987) [39] found that 10.5% of adolescent smokers purchased child packs in an effort to quit. Attempts to reduce cigarette consumption was also cited in the remaining eight qualitative investigations as the reason why smokers purchase kiddie packs. Despite studies indicating that kiddie packs cut cigarette consumption among current smokers, the quality of these studies is relatively low. Prior to reaching a conclusion, additional high-quality investigations are required. It is standard practise in the food industry to minimise the size of containers so as not to increase the price of the products consumers purchase, and this practise is effective. However, there is a counterargument stating that tobacco companies may limit the amount of smokes each package in order to conceal the price increase. Tobacco companies asserted that their marketing efforts had no effect on the initiation of tobacco use among young people and do not affect the general demand for tobacco products [56]. According to several studies, the marketing operations of the tobacco business have been the primary factor in attracting young people to tobacco use, deterring users from quitting, and increasing consumption among users [56]. Attempts to reduce or raise the amount of cigarettes per pack are often marketing strategies employed by one brand in competition with another to sell more cigarettes and boost profits. Wilson et al. [21] discovered that 15-count packages are marketed primarily to teens. Research done in Ireland indicated that 94% of kiddie pack purchasers claimed they were very or somewhat likely to continue smoking if cigarette prices remained the same [18]. If the price keeps the same, the kiddie pack had no effect on smoking rates. According to this study, pricing is the most effective method for regulating tobacco usage and addiction, particularly among price-sensitive young people. A price rise discourages youth from experimenting with tobacco products and discourages many current smokers from continuing. 77% of purchasers of a 10-pack stated that if the price of cigarettes increased by 100%, they would be unlikely to continue smoking. The introduction of a pack of 10 was aimed towards particularly sensitive adolescents. Thus, the present tobacco control regulations in many nations are supported for stopping this price-sensitive demographic from purchasing cigarettes. For instance, according to Malaysia's 2012 International Tobacco Control Report, tobacco taxes and prices have not risen at a rate sufficient to counterbalance income growth [57]. Therefore, the most effective method for reducing cigarette consumption is to drastically increase cigarette taxes. This will not only reduce the number of adult smokers, but it can also dissuade young people from starting to smoke. A tax increase will result in a 4% decrease in tobacco usage in high-income nations and a 5% decrease in low-and middle-income countries [4]. Access to kiddie packs is impeded by high taxes; enhancing the current tobacco policy control will continue to aid in preventing adolescents from smoking.
The included studies did not evaluate the impact of kiddie packs on the prevalence of smoking, nor did they discuss the introduction of kiddie packs to stimulate smoking initiation among non-smokers or among juveniles. However, there is evidence that teen smokers purchase kiddie packs far more frequently than adult smokers [18,21].
Even though the majority of research were of poor quality, the findings could be useful for policy implications. Compared to kiddie packs, which are cheaper and smaller, packs of 20 cigarettes with a higher price are a more effective strategy to fight the current problem [58]. This action will not solve the illegal cigarette trade, which we believe should be addressed in other ways, such as by improving enforcement and imposing harsher penalties on the traders [17,23].
In accordance with the Framework Convention on Tobacco Control (FCTC) of the World Health Organization (WHO) [19], many nations have outlawed the sale of single sticks and kiddie packs. On the other hand, numerous initiatives to reintroduce kiddie packs in an effort to prevent illegal cigarette sales are controversial. It was debated if it is preferable for smokers to purchase juvenile packs at a lower price than to purchase illegal cigarettes. However, our research indicates that kiddie packs tend to boost the desire to purchase cigarettes, particularly among adolescents.
The average quality score for all papers in this study was 34.8%, indicating that these investigations were of poor quality. Therefore, additional high-quality research is required for a definitive conclusion about the link with kiddie packs and smoking.
In general, kiddie pack research is often limited. We are unsure of the link between kiddie packs and smoking initiation. The majority of the documents were dated in the 1980s and 1990s, which may not reflect the current state of affairs. These publications were also sponsored by the industry, which can introduce bias into the aims and desired outcomes. Due to these circumstances, we were unable to evaluate the accuracy of certain research findings.

Conclusions
Based on the available evidence in this systematic review, there is evidence that kiddie packs are very preferentially bought by teenage smokers compared to adult smokers. In addition, there is some evidence that kiddie packs increase the urge or tendency to buy cigarettes, especially among both smoking youth and adults. The evidence supported the current tobacco policies of many countries in preventing minors and teenagers from purchasing cigarettes. We also found mixed evidence on whether kiddie packs reduce cigarette consumption. However, this study did not find conclusive evidence of the impact of kiddie packs on the initiation of smoking.
With the paucity of evidence-based research used in published studies and the absence of any clinical trials; this review highlights the need for better quality research data in the future. More independent tobacco company-sponsored studies are needed to identify the direct influence of kiddie cigarette packs on smoking so that it could help policymakers make a decision on creating or strengthening the existing tobacco control policies to make sure teenagers and minors are protected from the harmful effects of cigarettes.

Limitations
These findings should be interpreted with caution: (1) The methodological quality of some studies raises questions as most were low in quality due to insufficient information.
(2) the link between kiddie packs and smoking is not always the focus of the included studies. (3) causality findings can be deemed to be hasty as they are based on cross-sectional and qualitative study design.

Implication for Practice and Implication for Research
This review uncovered various concerns. First, most of the included studies were of poor quality and were not done by independent researchers (those who were not financed by a cigarette corporation), resulting in a conflict of interest. It is crucial to conduct independent research to draw more accurate conclusions about the outcome. In addition, further high-quality studies are required to assess the link between kiddie packs and smoking clearly and to replicate the method of doing the results to produce more useful data. Moreover, the studies revealed limited outcomes. There is evidence of an urge to buy kiddie packs, particularly among adolescents under 18 years of age due to their affordability. Thus, the current tobacco control measures, which prohibit the sale of kiddie packs, prevent price-sensitive youths from beginning smoking at a very young age. This would lower the burden on the government, as the economic consequences of tobacco use are large and include high health care expenses for treating diseases induced by tobacco use as well as lost human capital due to tobacco-attributable morbidity and mortality [4].