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Process Evaluation of a Clustered Randomized Control Trial of a Comprehensive Intervention to Reduce the Risk of Cardiovascular Events in Primary Health Care in Rural China

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School of Economics and Management, Guangzhou University of Chinese Medicine, Guangzhou 510006, China
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Department of STDs Prevention and Control, Dermatology Hospital, Southern Medical University, Guangzhou 510091, China
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Nuffield Centre for International Health and Development, University of Leeds, Leeds LS2 9JT, UK
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Division of Clinical Epidemiology &Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON M5T 3M7, Canada
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Zhejiang Provincial Centre for Disease Prevention and Control, Hangzhou 310052, China
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2020, 17(11), 4156; https://doi.org/10.3390/ijerph17114156
Received: 4 May 2020 / Revised: 26 May 2020 / Accepted: 8 June 2020 / Published: 10 June 2020
(This article belongs to the Section Global Health)
Background: Cardiovascular disease (CVD) is a major public health challenge in China. This study aims to understand the processes of implementing a comprehensive intervention to reduce CVD events in areas of drug therapy, lifestyle changes, and adherence support in a clustered randomized controlled trial (cRCT). This trial consisted of 67 clusters spanning over 3 years in Zhejiang Province, China. Method: A qualitative process evaluation was nested within the cRCT conducted in 9 township hospitals with 27 healthcare providers, 18 semi-structured interviews, and 23 observational studies of clinical practices within the intervention arm. Results: Effective and repeated trainings using an interactive approach were crucial to improve the prescribing behaviour of family doctors and their patient communication skills. However, the awareness of patients remained limited, thus compromising their use of CVD preventive drugs and adoption of healthy lifestyles. Health system factors further constrained providers’ and patients’ responses to the intervention. Financial barrier was a major concern because of the low coverage of health insurance. Other barriers included limited doctor–patient trust and suboptimal staff motivation. Conclusion: Our study suggests the feasibility of implementing a comprehensive CVD risk reduction strategy in China’s rural primary care facilities. However, health system barriers need to be addressed to ensure the success and sustainability of the intervention. View Full-Text
Keywords: cardiovascular diseases prevention; primary care; process evaluation; China cardiovascular diseases prevention; primary care; process evaluation; China
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MDPI and ACS Style

Zou, G.; Zhang, W.; King, R.; Zhang, Z.; Walley, J.; Gong, W.; Yu, M.; Wei, X. Process Evaluation of a Clustered Randomized Control Trial of a Comprehensive Intervention to Reduce the Risk of Cardiovascular Events in Primary Health Care in Rural China. Int. J. Environ. Res. Public Health 2020, 17, 4156. https://doi.org/10.3390/ijerph17114156

AMA Style

Zou G, Zhang W, King R, Zhang Z, Walley J, Gong W, Yu M, Wei X. Process Evaluation of a Clustered Randomized Control Trial of a Comprehensive Intervention to Reduce the Risk of Cardiovascular Events in Primary Health Care in Rural China. International Journal of Environmental Research and Public Health. 2020; 17(11):4156. https://doi.org/10.3390/ijerph17114156

Chicago/Turabian Style

Zou, Guanyang, Wei Zhang, Rebecca King, Zhitong Zhang, John Walley, Weiwei Gong, Min Yu, and Xiaolin Wei. 2020. "Process Evaluation of a Clustered Randomized Control Trial of a Comprehensive Intervention to Reduce the Risk of Cardiovascular Events in Primary Health Care in Rural China" International Journal of Environmental Research and Public Health 17, no. 11: 4156. https://doi.org/10.3390/ijerph17114156

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