Is There a Relationship between COVID-19 and Hyponatremia?
1
Department of Gastroenterology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania
2
Department of Gastroenterology, Clinical Emergency Hospital of Bucharest, 105402 Bucharest, Romania
3
Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, Romania
4
Department of Diabetes, Nutrition and Metabolic Diseases, “Carol Davila” University of Medicine and Pharmacy, 020475 Bucharest, Romania
5
Department of Visceral Surgery, Center of Excellence in Translational Medicine, Fundeni Clinical Institute, 022328 Bucharest, Romania
6
Department of Internal Medicine, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania
7
Department of Internal Medicine, Clinical Emergency Hospital of Bucharest, 105402 Bucharest, Romania
*
Author to whom correspondence should be addressed.
†
This author has equal contribution to the paper as the first author.
Medicina 2021, 57(1), 55; https://doi.org/10.3390/medicina57010055
Received: 13 December 2020
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Revised: 5 January 2021
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Accepted: 5 January 2021
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Published: 9 January 2021
(This article belongs to the Special Issue Interdisciplinary Medicine)
Nowadays, humanity faces one of the most serious health crises, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. The severity of coronavirus disease 2019 (COVID-19) pandemic is related to the high rate of interhuman transmission of the virus, variability of clinical presentation, and the absence of specific therapeutic methods. COVID-19 can manifest with non-specific symptoms and signs, especially among the elderly. In some cases, the clinical manifestations of hyponatremia may be the first to appear. The pathophysiological mechanisms of hyponatremia among patients with COVID-19 are diverse, including syndrome of inappropriate antidiuretic hormone secretion (SIADH), digestive loss of sodium ions, reduced sodium ion intake or use of diuretic therapy. Hyponatremia may also be considered a negative prognostic factor in patients diagnosed with COVID-19. We need further studies to evaluate the etiology and therapeutic management of hyponatremia in patients with COVID-19.
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Keywords:
SARS-CoV-2; COVID-19; SIADH; dyselectrolytemia; hyponatremia
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MDPI and ACS Style
Gheorghe, G.; Ilie, M.; Bungau, S.; Stoian, A.M.P.; Bacalbasa, N.; Diaconu, C.C. Is There a Relationship between COVID-19 and Hyponatremia? Medicina 2021, 57, 55. https://doi.org/10.3390/medicina57010055
AMA Style
Gheorghe G, Ilie M, Bungau S, Stoian AMP, Bacalbasa N, Diaconu CC. Is There a Relationship between COVID-19 and Hyponatremia? Medicina. 2021; 57(1):55. https://doi.org/10.3390/medicina57010055
Chicago/Turabian StyleGheorghe, Gina, Madalina Ilie, Simona Bungau, Anca M.P. Stoian, Nicolae Bacalbasa, and Camelia C. Diaconu. 2021. "Is There a Relationship between COVID-19 and Hyponatremia?" Medicina 57, no. 1: 55. https://doi.org/10.3390/medicina57010055
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