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Review

Psychic Life-Biological Molecule Bidirectional Relationship: Pathways, Mechanisms, and Consequences for Medical and Psychological Sciences—A Narrative Review

1
Department of Psychology, University “Vita e Salute”, San Raffaele, 20132 Milan, Italy
2
Italian Society of Psycho-Neuro-Endocrine-Immunology (SIPNEI), 00195 Rome, Italy
3
Department of Medicine, Public Health, Life and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, Italy
*
Author to whom correspondence should be addressed.
Academic Editors: Giuseppe Vitiello and Carlo Dal Lin
Int. J. Mol. Sci. 2022, 23(7), 3932; https://doi.org/10.3390/ijms23073932
Received: 11 February 2022 / Revised: 29 March 2022 / Accepted: 29 March 2022 / Published: 1 April 2022
(This article belongs to the Special Issue Brain/Mind Activity and Molecular Dynamics in Biological Systems)
Today, it is possible to investigate the biological paths and mechanisms that link mental life to biological life. Emotions, feelings, desires, and cognitions influence biological systems. In recent decades, psychoneuroendocrinoimmunology research has highlighted the routes linking the psyche–brain–immune systems. Recently, epigenetics research has shown the molecular mechanisms by which stress and mental states modulate the information contained in the genome. This research shapes a new paradigm considering the human being as a whole, integrating biology and psychology. This will allow us to progress towards personalized precision medicine, deeply changing medical and psychological sciences and clinical practice. In this paper, we recognize leading research on both bidirectional relations between the psyche–brain–immunity and molecular consequences of psychological and mental states. View Full-Text
Keywords: psychoneuroendocrinoimmunology; HPA axis; mental disorders; positive emotion; chronic stress; molecular consequences psychoneuroendocrinoimmunology; HPA axis; mental disorders; positive emotion; chronic stress; molecular consequences
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MDPI and ACS Style

Bottaccioli, A.G.; Bologna, M.; Bottaccioli, F. Psychic Life-Biological Molecule Bidirectional Relationship: Pathways, Mechanisms, and Consequences for Medical and Psychological Sciences—A Narrative Review. Int. J. Mol. Sci. 2022, 23, 3932. https://doi.org/10.3390/ijms23073932

AMA Style

Bottaccioli AG, Bologna M, Bottaccioli F. Psychic Life-Biological Molecule Bidirectional Relationship: Pathways, Mechanisms, and Consequences for Medical and Psychological Sciences—A Narrative Review. International Journal of Molecular Sciences. 2022; 23(7):3932. https://doi.org/10.3390/ijms23073932

Chicago/Turabian Style

Bottaccioli, Anna Giulia, Mauro Bologna, and Francesco Bottaccioli. 2022. "Psychic Life-Biological Molecule Bidirectional Relationship: Pathways, Mechanisms, and Consequences for Medical and Psychological Sciences—A Narrative Review" International Journal of Molecular Sciences 23, no. 7: 3932. https://doi.org/10.3390/ijms23073932

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