Short-Chained Platinum Complex Catalyzed Hydrosilylation under Thermomorphic Conditions: Heterogeneous Phase Separation at Ice Temperature

Homogeneous catalysts PtCl2[5,5′-bis-(n-ClCF2(CF2)3CH2OCH2)-2,2′-bpy] (2A) and PtCl2[5,5′-bis-(n-HCF2(CF2)3CH2OCH2)-2,2′-bpy] (2B), which contained short fluorous chains, were synthesized and used in catalysis of hydrosilylation of alkynes. In these reactions the thermomorphic mode was effectively used to recover these catalysts from the reaction mixture up to eight cycles by taking advantage of heterogeneous phase separation at ice temperature. This kind of catalysis had previously been observed in fluorous catalysts of platinum containing about 50% F-content, but in this work the percentage of F-content is decreased to only about 30%, by which we termed them as “very light fluorous”. Our new type of catalyst with limited number of F-content is considered as the important discovery in the fluorous technology field as the reduced number of fluorine atoms will help to be able to comply the EPA 8-carbon rule. The metal leaching after the reaction has been examined by ICP-MS, and the testing results show the leaching of residual metal to be minimal. Additionally, comparing these results to our previous work, fluorous chain assisted selectivity has been observed when different fluorous chain lengths of the catalysts are used. It has been found that there exists fluorous chain assisted better selectivity towards β-(E) form in the Pt-catalyzed hydrosilylation of non-symmetric terminal alkyne when the Pt catalyst contains short fluorous chain (i.e., 4 Cs). Phenyl acetylenes showed the opposite regioselectivity due to pi-pi interaction while using the same catalyst via Markovnikov’s addition to form terminal vinyl silane, which is then a major product for Pt-catalyzed hydrosilylation of terminal aryl acetylene with triethylsilane. Finally, the kinetic studies indicate that the insertion of alkyne into the Pt-H bond is the rate-determining step.


Introduction
Developing recyclable catalysts, able to reduce the waste of expensive transition metals is one of the important issues in sustainable research. Generally, homogeneous catalysts have good catalytic activity but they have limitation on separation catalytic recovery [1], whereas heterogeneous catalysts are easily recyclable but with low catalytic activity [2][3][4]. A valuable method, called thermomorphic system provides a good resolution which makes the catalyst dissolve in one condition but precipitate in another. Using the special solubility selectivity of fluorous chain-containing metal complex [5,6] is very promising for the catalytic thermomorphic system in the development of fluorine chemistry [7].
Many polyfluorinated chain-containing metal complexes are used in the fluorous biphasic system (FBS) [8] which is an immiscible two-solvent system having one fluorous solvent and a common organic one. After reaction completion, the fluorous chaincontaining metal complexes can be easily extracted from the fluorous solvent while the other organic products stay in organic layer. To ensure the good solubility for fluorous chain-containing compounds soluble in fluorous solvents, "heavy fluorous content" [9] (more than 60% fluorine content, F-content) is required. This may result in a big drawback [10]; that is the need for expensive fluorous starting material and the solvent. To reduce the F-content of compounds and fluorous solvent, an alternative way is to use the different solubility of "light fluorous compounds" (less than 60% of F-content) [5,11] between high and low temperature in a common organic solvent. In this method, a fluorous chain-containing metal catalyst could be soluble at high temperature during the catalytic reactions, but insoluble at room temperature (or lower temperature) for the recovery of catalysts via a simple liquid-solid separation [12][13][14][15][16][17]. This is a typical application of "light fluorous" metal catalysts in the so-called "thermomorphic condition".
A variety of fluorous chain-containing metal complexes have been synthesized in our laboratory and studied for the possible applications [18,19]. In 2016, we have demonstrated the first example of using a fluorous chain-containing Pt complex with heavy fluorine content {[PtCl 2 [5,5 -bis-(n-C 11 F 23 CH 2 OCH 2 )-2,2 -bpy] (3a), with 53% F-content for the Pt catalyst} successfully catalyzed the hydrosilylation of alkynes in dibutyl ether (DBE) under thermomorphic condition [19]. The results of the catalytic hydrosilylation reaction showed high reaction yields, good turnover numbers and good recovery of the catalyst for up to 8 times of re-usage with very low leaching level of Pt (ca. 0.001%).
It is important [42] that we could further lower the F-content of catalyst, in a way that its F-content is even lower than that of so-called "light fluorous" catalyst; and is without compromising the separation effectiveness, so they become readily adapted to the conventional chemical and biochemical processes. In this work, the even shorter fluorous chain-containing platinum catalysts, [PtCl 2 (5,5 -bis(CH 2 OCH 2 C 4 F 8 Cl)-2,2 -bpy)] (2A) and [PtCl 2 (5,5 -bis(CH 2 OCH 2 C 4 F 8 H)-2,2 -bpy)] (2B) with the even lower fluorine content (i.e., 31.0 and 33.4% F-content for 2A and 2B, respectively.) have been synthesized and been applied to catalyze the hydrosilylation reactions of internal and terminal alkynes. To the best of our knowledge, this is the first example of the application of very short polyfluorinated Pt complexes as effective, recoverable hydrosilylation catalysts under thermomorphic condition showing heterogeneous phase separation at ice temperature. These "very light fluorous" Pt complexes 2A and 2B feature on homogeneously catalyzing reaction at high temperature in common organic solvent and turning to the heterogeneous precipitation at lower temperature under thermomorphic condition. Taking into consideration of their good catalytic capabilities and good thermal stability, these catalysts could be regarded as the very good alternatives to most of the homogeneous catalysts.
It is important [42] that we could further lower the F-content of catalyst, in a way that its F-content is even lower than that of so-called "light fluorous" catalyst; and is without compromising the separation effectiveness, so they become readily adapted to the conventional chemical and biochemical processes. In this work, the even shorter fluorous chain-containing platinum catalysts, [PtCl2(5,5′bis(CH2OCH2C4F8Cl)-2,2′-bpy)] (2A) and [PtCl2(5,5′-bis(CH2OCH2C4F8H)-2,2′bpy)] (2B) with the even lower fluorine content (i.e., 31.0 and 33.4% F-content for 2A and 2B, respectively.) have been synthesized and been applied to catalyze the hydrosilylation reactions of internal and terminal alkynes. To the best of our knowledge, this is the first example of the application of very short polyfluorinated Pt complexes as effective, recoverable hydrosilylation catalysts under thermomorphic condition showing heterogeneous phase separation at ice temperature. These "very light fluorous" Pt complexes 2A and 2B feature on homogeneously catalyzing reaction at high temperature in common organic solvent and turning to the heterogeneous precipitation at lower temperature under thermomorphic condition. Taking into consideration of their good catalytic capabilities and good thermal stability, these catalysts could be regarded as the very good alternatives to most of the homogeneous catalysts.
(a) Symmetrical internal alkyne The Pt catalyst (2A or 2B)-catalyzed hydrosilylation of 5-decyne (4) with triethylsilane (3) under thermomorphic condition was successfully carried out to afford product 4a in quantitative conversions, as shown in Scheme 2, whereas no product 4a could be found in the reaction without using Pt catalyst for 24 h. The best reaction condition for the catalyst 2A was optimized at 120 • C for 2 h via the GC-MS examination of the reaction while the NMP was used as the internal standard. The quantitative conversion of the hydrosilylations were still observed even over the eight cycles of Pt catalyst recycling almost without decreasing  Table 1). The similar catalytic effect on the converting yield is also shown by Pt catalyst 2B whose structure is to have H atom to replace Cl atom of 2A at the terminal of fluorous chains. triethylsilane (3) under thermomorphic condition was successfully carried out to afford product 4a in quantitative conversions, as shown in Scheme 2, whereas no product 4a could be found in the reaction without using Pt catalyst for 24 h. The best reaction condition for the catalyst 2A was optimized at 120 °C for 2 h via the GC-MS examination of the reaction while the NMP was used as the internal standard. The quantitative conversion of the hydrosilylations were still observed even over the eight cycles of Pt catalyst recycling almost without decreasing the activity under the thermomorphic condition ( Table 1). The similar catalytic effect on the converting yield is also shown by Pt catalyst 2B whose structure is to have H atom to replace Cl atom of 2A at the terminal of fluorous chains.  Generally, catalysts with high F-content have good performance under thermomorphic condition, e.g., PtCl2[5,5′-bis-(n-C11F23CH2OCH2)-2,2′-bpy] (55-23F-PtCl2) reported in our previous work (with C11F23 moiety, %F = 53) [19], but the catalyst 2A here only containing "very-light fluorous" chain (e.g., C4F8, %F = 31) still showed the impressive catalytic activity and efficient recovery under thermomorphic condition (Figures S1 and S3) shown in Table 1.
Generally speaking, typical Pt-based catalysts for the hydrosilylation of alkynes can be used at significantly lower Pt/substrate ratios than 1 mol% loading. We mainly use 1 mol% of catalyst 2A loading because the scope of this study is on recycling and reuse of catalyst. The hydrosilylation of 5-decyne (4) with triethylsilane (3) was also reported by F. Alonso's group using Pt/TiO 2 as the catalyst by using more stringent catalytic loading of 0.25 mol% [44]. They showed catalytic results under very short reaction time (less than 2 h) at first two catalytic reaction cycles, but the catalyst's activity was significantly decreased to make the third-cycle reaction taking 3 h for the same conversion and the fifth-cycle reaction giving only 62% conversion after 24 h. In contrast, the fifth-cycle hydrosilylation in our work still had very good performance of 99.5% conversion (entry 5 in Table 1), which indicates that Pt catalyst 2A is both very efficient and robust. The Pt catalyst 2A-catalyzed hydrosilylations of 5-decyne (4) with triethylsilane (3) in Bu 2 O have also been studied kinetically at 120 and 130 • C. These two sets of data points are shown in Section S3 in Supplementary Materials. In both cases, the integrated rate law derived from the alkyne concentration vs time plots is ln[5-decyne] = ln[5-decyne] 0 -kt, with k = 0.069 (R 2 = 0.95) & 0.099 (R 2 = 0.99) at 120 • C and 130 • C, respectively. [Note: ln[5-decyne] 0 = 0]; at 130 • C the derived ln[5-decyne] 0 value is very close to 0]. The first reaction order with respect to the alkyne suggests that the insertion of the latter into the Pt-H bond is the rate-determining step, in agreement with the recent results reported by Kuhn's group [45]. These two kinetically monitored reactions at 0.5 h show the respective turnover frequencies (TOF) are 174 and 198 h −1 . These data show that 2A is recoverable, robust and catalytically effective. The Pt catalyst 2A-catalyzed hydrosilylation of 5-decyne (4) and dimethylphenylsilane (3 ) was also carried out in a shorter reaction time (ca. 40 min) to afford only E-form product of 4c based on the GC-MS analysis, as shown in Scheme 3. The good recycling results under the thermomorphic condition were also confirmed by the nearly quantitative conversion of the hydrosilylation catalyzed by the reused Pt catalyst for up to eight cycles ( Table 2) with very good turnover number (TON =~100). 0.99) at 120 °C and 130 °C, respectively. [Note: ln[5-decyne]0 = 0]; at 130 °C the derived ln[5-decyne]0 value is very close to 0.]. The first reaction order with respect to the alkyne suggests that the insertion of the latter into the Pt-H bond is the rate-determining step, in agreement with the recent results reported by Kuhn's group [45]. These two kinetically monitored reactions at 0.5 h show the respective turnover frequencies (TOF) are 174 and 198 h −1 . These data show that 2A is recoverable, robust and catalytically effective.
The Pt catalyst 2A-catalyzed hydrosilylation of 5-decyne (4) and dimethylphenylsilane (3′) was also carried out in a shorter reaction time (ca. 40 min) to afford only E-form product of 4c based on the GC-MS analysis, as shown in Scheme 3. The good recycling results under the thermomorphic condition were also confirmed by the nearly quantitative conversion of the hydrosilylation catalyzed by the reused Pt catalyst for up to eight cycles ( Table 2) with very good turnover number (TON = ~100).    (3) with terminal alkyne [i.e., 1-decyne (5) or 1-hexyne (6)] under thermomorphic mode is shown in Scheme 4. The hydrosilylation of 1-decyne (5) with triethylsilane (3) afforded two products, triethyl(dec-1en-2-yl)silane (5a) and (E)-triethyl(dec-1-en-1-yl)silane (5b) with a GC-MS or NMR method to monitor the reaction and to determine the products under thermomorphic condition. This hydrosilylation also showed very good recycling results under thermomorphic condition. The structure of 5a and 5b were identified by the 1 H-NMR spectrum of their mixture (see Figure S7). The signals of H a and H a' of 5a are shown as two doublet peaks at 5.2 and 5.6 ppm with a coupling constant of 2.7 Hz, which is consistent to that of geminal alkenyl protons. For 5b, the H b' shows a doublet-triplet splitting peak and the H b shows a doublet peak with a coupling constant of 18.9 Hz, which represents for the alkenyl protons at the trans position. The ratio of 5a and 5b determined from the integration of 1 H-NMR spectrum equals to 1:2, which is almost similar to the ratio from GC-MS method (1:1.82) (see entry 5 in Table 3). The Pt complex 2A-catalyzed hydrosilylation of triethylsilane (3) with terminal alkyne [i.e., 1-decyne (5) or 1-hexyne (6)] under thermomorphic mode is shown in Scheme 4. The hydrosilylation of 1-decyne (5) with triethylsilane (3) afforded two products, triethyl(dec-1-en-2-yl)silane (5a) and (E)-triethyl(dec-1en-1-yl)silane (5b) with a GC-MS or NMR method to monitor the reaction and to determine the products under thermomorphic condition. This hydrosilylation also showed very good recycling results under thermomorphic condition. The structure of 5a and 5b were identified by the 1 H-NMR spectrum of their mixture (see Figure S7). The signals of Ha and Ha' of 5a are shown as two doublet peaks at 5.2 and 5.6 ppm with a coupling constant of 2.7 Hz, which is consistent to that of geminal alkenyl protons. For 5b, the Hb' shows a doublet-triplet splitting peak and the Hb shows a doublet peak with a coupling constant of 18.9 Hz, which represents for the alkenyl protons at the trans position. The ratio of 5a and 5b determined from the integration of 1 H-NMR spectrum equals to 1:2, which is almost similar to the ratio from GC-MS method (1:1.82) (see entry 5 in Table 3).  Commented   (6)) recycling data are shown in Table S1 in Supplementary Materials.
The other terminal alkyne, 1-hexyne (6) also underwent the hydrosilylation reaction with triethylsilane (3) in the presence of Pt catalyst 2A successfully (Scheme 4). The reaction was completed within 30 min to produce two isomers α-form 6a and β-(E)-form 6b whose 1 H-NMR spectrum shows similar characteristic peaks (see Figure S8) to that of α-form 5a and β-(E)-form 5b. The signals for H a and H a' of 6a are 5.3 ppm (dt, J = 3.3, 1.2 Hz) and 5.6 ppm (dt, J = 3.3, 1.5 Hz); and the signals for H b and H b of 6b are 5.5 ppm (dt, J = 18.6, 1.5 Hz) and 6.0 ppm (dt, J = 18.6, 6.3 Hz), respectively. As shown in entry 1 of Table S1, the ratio of 6a and 6b is approximately 1:4.7 estimated by a GC-MS method.
b.2. One functionalized terminal alkyl acetylene (propargyl alcohol) In Scheme 5, the hydrosilylation of 2-methylbut-3-yn-2-ol (7), a terminal alkyne with a bulky substituent (hydroxyisopropyl) with triethylsilane (3) for 1 h afforded two isomers, α-form 7a and β-(E)-form 7b in 99.4% yield with an estimated ratio of 1:2.1 from GC data, and/or 1:2.3 from 1 H-NMR spectra. The good recycling results for this reaction were shown in Table 4. When comparing with the previously reported long fluorous chained platinum complex (α:β = 1:2) [19], a slightly better selectivity was observed in this work by using Pt catalyst 2A (1:2.3). Although the heterogeneous catalyst PtO/PtO 2 -Fe 3 O 4 in literature [46] showed a better selectivity for 7a and 7b (1:3.5), it is worth mentioning that the Pt complex 2A in this work still has good selectivity among a homogeneous type of catalysts.  [46] showed a better selectivity for 7a and 7b (1:3.5), it is worth mentioning that the Pt complex 2A in this work still has good selectivity among a homogeneous type of catalysts.     (3) for 1~3 h under thermomorphic condition afforded two isomers, α-form 8a and β-(E)-form 8b with an estimated ratio of 2:1 according to GC-MS analysis. The characteristic 1 H-NMR signals (see Figure S9) for the geminal alkenyl protons of α-form 8a appear at 5.6 ppm (d, J = 3 Hz) and 5.9 ppm (d, J = 3 Hz), and the signals for the trans position protons of (E)-form 8b show at 6.4 ppm (J = 18.9 Hz) and 6.9 ppm (J = 19.5 Hz). Most of the ratios of 8a and 8b determined by the integration of 1 H-NMR spectrum are close to 2:1. (c) Three terminal aryl acetylenes In Scheme 6, the Pt catalyst 2A-catalyzed hydrosilylation of phenylacetylene (8) with triethylsilane (3) for 1~3 h under thermomorphic condition afforded two isomers, α-form 8a and β-(E)-form 8b with an estimated ratio of 2:1 according to GC-MS analysis. The characteristic 1 H-NMR signals (see Figure S9) for the geminal alkenyl protons of α-form 8a appear at 5.6 ppm (d, J = 3 Hz) and 5.9 ppm (d, J = 3 Hz), and the signals for the trans position protons of (E)-form 8b show at 6.4 ppm (J = 18.9 Hz) and 6.9 ppm (J = 19.5 Hz). Most of the ratios of 8a and 8b determined by the integration of 1 H-NMR spectrum are close to 2:1. Which is consistent to the ratio from GC-MS data in Table 5. Interestingly, the major product for the hydrosilylation of the terminal aryl acetylene (8) is thermodynamically unfavored α-form 8a, whereas the major products for the Which is consistent to the ratio from GC-MS data in Table 5. Interestingly, the major product for the hydrosilylation of the terminal aryl acetylene (8) is thermodynamically unfavored α-form 8a, whereas the major products for the alkyl acetylenes (5, 6 and 7) are thermodynamically favored β-(E)-form 5b, 6b and 7b. The selectivity of ratio of 8a:8b decreased after 6 runs is because some of the catalysts start to degrade during the course of repeated reactions. When we compare the efficiency of our catalyst 2A with a heterogeneous molecular complex immobilized on the surface of graphene, catalyst 2A showed better catalytic efficiency at the elevated temperature. Mata [35] and his colleagues used 1 mol% catalytic loading of their catalyst in the similar reactions to obtain 40% yield after 3 h where TON and TOF are 40 and 13, respectively. They have further optimized the reaction and used 0.5 mol% loading to obtain 94% yield after 20 h. Where TON and TOF are 188 and 9.4, respectively. However, we have obtained on average 100% yield in 2 h with TON and TOF values of 100 and 50, respectively.
According to the literatures, which isomer being the major product for the hydrosilylation of phenylacetylene depends on the different catalysts. The thermodynamically stable β-(E)-isomer was the major product when the hydrosilylation was catalyzed with a homogeneous Karstedt's catalyst at 60 • C for 1 h, and the product ratio was β-(E):β-(Z): α isomers = 81:1:18 [30]. However, the α isomer was the major product when it was catalyzed by a  [44] with the product ratio of β-(E):α = 26:74 and the conversion 39% for THF and 50% for water as the solvents, respectively. Comparatively, using the Pt catalyst 2A in this work which was homogeneous under thermomorphic mode, but provided thermodynamically unfavored α-form as the major product with better conversions (mostly more than 99%) and shorter reaction time (1~3 h).
Lastly, to further understand this unusual product selectivity, two more substituted phenyl acetylenes with electron-withdrawing fluoro group and electron-donating methyl group were brought to this 2A catalyzed hydrosilylation under thermomorphic mode. The hydrosilylation of 4-fluorophenylacetylene (9) at 120 • C for 4~5 h afforded α-form isomer as the major product in 99% high yield with the product ratio of 9a:9b = 2.54:1 (estimated by GC) (Table S2). Similarly, the hydrosilylation of 4-methylphenylacetylene (10) at 120 • C for 2~5 h also produced α-form isomer as the major product in 99% high yield with the product ratio of approximately 10a:10b = 2.13:1 estimated by GC (entry 4, Table S3). The results of hydrosilylation reactions of either 4-fluorophenylacetylene (9)  To understand the better product ratio from the Pt complex 2A-catalyzed hydrosilylation (short-fluorous-chains), a plausible mechanism containing the geometry of Pt complex was proposed. The optimized structure of 2A in the gaseous phase has been obtained by DFT theoretical calculation, showing the two fluorous side-chains whose -CH 2 OCH 2 -R f moieties can form the two five-membered rings at the both sides of 5,5 -substituted bipyridine to extend the metal planarity (in Figure 1 and Figure S10 of Supplementary Materials). Similar type of extended the Pt metal planarity (with U-shaped like arrangement) has been found on the experimental data of 55-8FH-PtI2 (see Figure S11) in our previous research [47]. This optimized 2A arrangement also shows the intramolecular five-membered ring and other weak interactions (see Figure S10); and also be observed to be similar to that of the complexes 55-4FH-MX2, where X = Br or I; M = Pt, with the loop structure reported by our group [48] (see Figure S12).
As shown is Figure 1 which is similar to Chalk-Harrod mechanism, the proposed mechanism for 2A-catalyzed hydrosilylation of terminal aliphatic alkyne with triethylsilane is described in a 3D-view instead of 2D-view of a well-known Chalk-Harrod mechanism. Firstly, in species I the 2A catalyst is believed to appear in the reduced form, Pt(0) [49] at the elevated temperature. Besides the planar Pt(bpy) core, the Pt complexes which contain two intramolecular five-membered ring in the species I, II, III and IV can extend its planarity with slight U-shaped structure. The Et 3 SiH is oxidatively added to [Pt], followed by coordination of the alkyne and insertion to Pt-H bond. Thus, the electronic effect due to the polarization of an alkyne in hydrosilylation would direct the hydride addition to the more electropositive C-atom (in II). After the oxidative addition of silane, the alkyne is shown by approaching from the top of the Pt(bpy)-based molecular plane. When the alkyne (the 2nd reactant) has been attached to the Pt, this step of migration-insertion shows that the R group of the alkyne (III at bottom) has been forced to keep away from the silyl-group side of the metal complex (in IV) which then leads to generate β-(E) form as the major product. This addition shows the anti-Markovnikov's selectivity. This proposed mechanism reasonably explains the better product ratio of β-(E) to α in 1-decyne (5), 1-hexyne (6) and propargyl alcohol (7) in the hydrosilylations catalyzed by Pt catalyst 2A in this study. However, if the R group is the aromatic moiety, then the bond axis of the linear aryl acetylene molecule (H-C≡C-R) rotates more than 90 o with respect to Pt-b axis (which is the molecular plane normal) (see Figure 1). For example, in an extreme case, if the tilting angle is equal to 180 • , then it is like the linear molecule is exactly flipped over (R-C≡C-H). Such a phenomenon occurs possibly due to steric reason and other weak interactions (e.g., pi-pi interaction), when linear aromatic alkyne in species III is attached to the Pt center. Thus, 2A-catalyzed hydrosilylation of terminal aryl acetylenes with triethylsilane gives rise to the α isomer as the major product.  To understand the better product ratio from the Pt complex 2A-catalyzed hydrosilylation (short-fluorous-chains), a plausible mechanism containing the geometry of Pt complex was proposed. The optimized structure of 2A in the gaseous phase has been obtained by DFT theoretical calculation, showing the two fluorous side-chains whose -CH2OCH2-Rf moieties can form the two five-membered rings at the both sides of 5,5′-substituted bipyridine to extend the metal planarity (in Figure 1 and Figure S10 of Supplementary Materials). Similar type of extended the Pt metal planarity (with U-shaped like arrangement) has been found on the experimental data of 55-8FH-PtI2 (see Figure S11) in our previous research [47]. This optimized 2A arrangement also shows the intramolecular five-membered ring and other weak interactions (see Figure S10); and also be observed to be similar to that of the complexes 55-4FH-MX2, where X = Br or I; M = Pt, with the loop structure reported by our group [48] (see Figure S12).

Detection of Metal Recovery by ICP-MS
After discussing the hydrosilylation reaction of alkyne substrates, we randomly used ICP-MS to detect the leakage of metal catalysts, as shown in Table 6. The quantity of residual Pt metal present in the solution was analyzed, taking random samples among the product solutions resulting from the thermomorphic hydrosilylation. Only very low Pt leaching was observed in solution from the complex 2A-and 2B-catalyzed hydrosilylations under thermomorphic conditions. The residual platinum content in the product is only minimal since the recovery rate is greater than 99 %. Looking at the leaching test results, whether it is for 2A or 2B, the measured platinum content is in the ppb level even after the 8 times of repeated recycling. It can be concluded that the metal catalyst used in this experiment not only effectively catalyzes hydrosilylation, but also easily achieved with almost no Pt leaching during the recycling processes.  In order to evaluate the effect of a series of fluorous chain on the Pt catalyst recovery, the fluorinated moieties of R f = CF 3 , C 4 F 8 Cl (C 4 F 8 H), C 8 F 16 H and C 11 F 23 in the fluorous chain have been investigated for the systematic purpose. In other words, for the fluorous chains with R f = CF 3 and C 8 F 16 H moieties which are from respective [PtCl 2 (5,5 -bis(CH 2 OCH 2 CF 3 )-2,2bpy)] (2C) and [PtCl 2 (5,5 -bis(CH 2 OCH 2 C 8 F 16 H)-2,2 -bpy)] (2D) complexes have also studied to give a trend for the series (see Section S7 in Supplementary Materials). When R f = CF 3 group, it has been found that 55-3F-PtCl 2 (2C) is totally soluble in DMF and moderately soluble in Bu 2 O. The images of these solubility properties are shown in Section S7 of Supplementary Materials (see Figure S13a,b). Thus, complex 2C with one carbon fluoro-chain which is so short that it cannot give the useful heterogeneous phase separation property at room temperature for the recycling studies here. When R f = C 8 F 16 H group which is sparingly soluble in Bu 2 O ether (solubility image is shown in Figure S14 in Supplementary Materials).

General Procedures
HP 6890 GC containing a 30 m 0.250 mm HP-1 capillary column with a 0.25 mm stationary phase film thickness was used to censor the reaction. The same GC instrument with a 5973 series mass selective detector was used to Acquire GC/MS data. The flow rate was 1 mL/min and splitless. Samples analyzed by fast atom bombardment (FAB) mass spectroscopy were done by the staff of the National Central University (Taoyuan, Taiwan) mass spectrometry laboratory. The amounts of residual Pt samples were analyzed by ICP-MS. Infra-red spectra were obtained on a Perkin Elmer RX I FT-IR Spectrometer. NMR spectra were recorded on Bruker AM 500 and Joel AM 200 using 5 mm sample tubes. CD 3 OD, CD 2 Cl 2 , CDCl 3 , deuterated DMF and deuterated DMSO were the references for both 1 H-and 13 C-NMR spectra; and Freon ® 11 (CFCl 3 ) was the reference for 19 F NMR spectra.

General Procedures in Catalytic Hydrosilylation Reaction and Recovery
In a typical run, an alkyne (2 mmol) and silane (2 mmol) were charged into 10 mL reaction tube containing a magnetic stirrer bar, then the Pt catalyst (1 mol%) and followed by dibutyl ether, DBE, solvent (2 mL). Then the reaction mixture was set to react at 120 • C for the given period of time before GC/MS analysis was done to confirm the completion of the reaction. Once the catalytic recovery was done, the pure product was isolated by using CH 2 Cl 2 /water extraction and the CH 2 Cl 2 layer was pumped under reduced pressure to obtain the pure product. The product was finally analyzed by using 1 H-NMR spectroscopy.
The Pt-catalyzed hydrosilylation reactions of all the alkyne substrates with 3 were carried out under the thermomorphic condition that effectively confirmed the practicability of reutilizing the catalyst in Bu 2 O solvent. Every round the catalytic reaction was performed at 120 • C under N 2 gas. At the end of each run, the product mixtures were put into freezer (0 • C) for about 5 min, and then centrifuged to separate the catalyst and reaction mixture (see Scheme S1 in Supplementary Materials). After catalyst was recovered by decantation and washed three times by the same solvent, it was again supplied with the same amounts of Bu 2 O solvent, the alkyne substrate, and HSiEt 3 to continue to the next round. The products were tracked with GC-MS and 1 H-NMR, using NMP as internal standard until the end of the reaction was confirmed.

Starting Materials
Chemicals, reagents, and solvents employed were commercially available and used as received. H(CF 2 ) 4 CH 2 OH and Cl(CF 2 ) 4 CH 2 OH were purchased from either Aldrich or SynQuest.

Conclusions
Concerns for the environment and scarcity of resources is becoming a challenge which motivates chemists to look for more economical and more ecofriendly process. Therefore, developing a recoverable catalyst with a better activity, better selectivity, and easier separation, with a better yield is everyone's goal. Reported here, this work showed effective catalysis by using shortest fluoro-chain complexes containing the (%)F-content being less than 35 wt.%. The catalyst was very effectively recycled up to eight times for all the experiments done, but almost without affecting its activity and selectivity. In these reactions the thermomorphic mode was effectively used to recover these short fluorous ponytailed catalysts from the reaction mixture up to eight cycles by using heterogeneous phase separation at 0 • C. The product yield was also higher in every reaction run; sometimes it reached to even 100%. The metal leaching studies via ICP-MS method showed that the metal in the complex is effectively recovered throughout the catalytic cycles with very little loss, which is almost negligible. Additionally, the kinetic studies have been carried out for 2A-catalyzed hydrosilylations of 5-decyne (4) with triethylsilane (3) in Bu 2 O at 120 and 130 • C. The results showed that the 1st order kinetics where the rate is directly proportional to the concentration of 5-decyne. Thus, we suggest that the insertion of alkyne into the Pt-H bond is the rate-determining step which agrees well with recent results reported by Kuhn et al. [45]. Furthermore, the regioselectivity followed the Chalk-Harrod mechanism as it undergoes the syn kind of reaction to give α and β-(E) products, of which the β-(E) was the major form for most of the cases. Funding: MOST 106-2113-M-027-001 and university joint grants: NTUT-CGMH-108-03 and NTUT-CGMH-106-7 (or CORPG3G0071).

Data Availability Statement:
The data presented in this study are available in the article and supplementary materials.