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Open AccessFeature PaperArticle

Sustainable and Selective Extraction of Lipids and Bioactive Compounds from Microalgae

1
Dipartimento di Ingegneria per l’Ambiente e il Territorio e Ingegneria Chimica, Università della Calabria, Cubo 45A, I-87036 Rende, Italy
2
Dipartimento di Scienze della Salute, Università Magna Græcia, Viale Europa, I-88100 Germaneto (CZ), Italy
3
CREA Research Centre for Olive, Citrus and Tree Fruit, C.da Li Rocchi, I-87036 Rende, Italy
4
Dipartimento di Chimica e Tecnologie Chimiche, Università della Calabria, Cubo 12C, I-87036 Rende, Italy
*
Authors to whom correspondence should be addressed.
Academic Editors: Monica Nardi, Antonio Procopio and Maria Luisa Di Gioia
Molecules 2019, 24(23), 4347; https://doi.org/10.3390/molecules24234347
Received: 7 November 2019 / Revised: 20 November 2019 / Accepted: 27 November 2019 / Published: 28 November 2019
The procedures for the extraction and separation of lipids and nutraceutics from microalgae using classic solvents have been frequently used over the years. However, these production methods usually require expensive and toxic solvents. Based on our studies involving the use of eco-sustainable methodologies and alternative solvents, we selected ethanol (EtOH) and cyclopentyl methyl ether (CPME) for extracting bio-oil and lipids from algae. Different percentages of EtOH in CPME favor the production of an oil rich in saturated fatty acids (SFA), useful to biofuel production or rich in bioactive compounds. The proposed method for obtaining an extract rich in saturated or unsaturated fatty acids from dry algal biomass is disclosed as eco-friendly and allows a good extraction yield. The method is compared both in extracted oil percentage yield and in extracted fatty acids selectivity to extraction by supercritical carbon dioxide (SC-CO2). View Full-Text
Keywords: algal oil; green chemistry; green solvents; extraction; biofuel; bio compound algal oil; green chemistry; green solvents; extraction; biofuel; bio compound
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MDPI and ACS Style

Santoro, I.; Nardi, M.; Benincasa, C.; Costanzo, P.; Giordano, G.; Procopio, A.; Sindona, G. Sustainable and Selective Extraction of Lipids and Bioactive Compounds from Microalgae. Molecules 2019, 24, 4347. https://doi.org/10.3390/molecules24234347

AMA Style

Santoro I, Nardi M, Benincasa C, Costanzo P, Giordano G, Procopio A, Sindona G. Sustainable and Selective Extraction of Lipids and Bioactive Compounds from Microalgae. Molecules. 2019; 24(23):4347. https://doi.org/10.3390/molecules24234347

Chicago/Turabian Style

Santoro, Ilaria; Nardi, Monica; Benincasa, Cinzia; Costanzo, Paola; Giordano, Girolamo; Procopio, Antonio; Sindona, Giovanni. 2019. "Sustainable and Selective Extraction of Lipids and Bioactive Compounds from Microalgae" Molecules 24, no. 23: 4347. https://doi.org/10.3390/molecules24234347

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