Next Article in Journal
Induction of Apoptosis in Human Breast Adenocarcinoma Cells MCF-7 by Monapurpyridine A, a New Azaphilone Derivative from Monascus purpureus NTU 568
Previous Article in Journal
Synthesis of New Liquid Crystalline Diglycidyl Ethers
Article Menu

Export Article

Open AccessArticle
Molecules 2012, 17(1), 657-663;

A New Prenylated Flavanone from Derris trifoliata Lour.

Department of Pharmacy, Medical College, Hunan Normal University, Changsha 410006, China
Key Laboratory of Marine Bio-resourses Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China
These authors contributed equally to this work.
Authors to whom correspondence should be addressed.
Received: 30 October 2011 / Revised: 26 December 2011 / Accepted: 27 December 2011 / Published: 11 January 2012
(This article belongs to the Section Natural Products Chemistry)
Full-Text   |   PDF [189 KB, uploaded 18 June 2014]   |  


A new flavanone, 4′,5,7-trihydroxy-6,8-di-(2-hydroxy-3-methylbut-3-enyl)- flavanone, was isolated from the aerial parts of Derris trifoliate, together with eleven known compounds: rotenone, tephrosin, 12a-hydroxyrotenone, deguelin, 6a,12a-dehydro-rotenone, dehydrodeguelin, 7a-O-methyldeguelol, 7a-O-methylelliptonol, 5,7,3',4'-tetra-hydroxy-6,8-diprenylisoflavone, daidzein and 4'-hydroxy-7-methoxyflavanone. 7a-O-Methylelliptonol was isolated for the first time from the genus Derris. Their structures were characterized on the basis of spectral data. Eight of the isolated compounds were found to be significantly toxic to brine shrimp (LC50 range 0.06–9.95 μg/mL). The new compound showed weak toxicity (LC50 = 211.31 μg/mL). View Full-Text
Keywords: Derris trifoliate; aerial part; prenylated flavanone; rotenoids; brine shrimp toxicity Derris trifoliate; aerial part; prenylated flavanone; rotenoids; brine shrimp toxicity

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Supplementary material


Share & Cite This Article

MDPI and ACS Style

Jiang, C.; Liu, S.; He, W.; Luo, X.; Zhang, S.; Xiao, Z.; Qiu, X.; Yin, H. A New Prenylated Flavanone from Derris trifoliata Lour.. Molecules 2012, 17, 657-663.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top