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Open AccessFeature PaperCase Report

Pleomorphic Adenoma of External Auditory Canal: Case Report of First Endoscopic Resection and Literature Review

1
Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland
2
Institute of Pathology, University of Bern, 3010 Bern, Switzerland
*
Author to whom correspondence should be addressed.
Equal last shared authorship.
Medicina 2020, 56(5), 248; https://doi.org/10.3390/medicina56050248
Received: 7 April 2020 / Revised: 14 May 2020 / Accepted: 15 May 2020 / Published: 20 May 2020
(This article belongs to the Section Oncology)
Ceruminous pleomorphic adenoma is a very rare, mostly benign tumor originating from the ceruminal glands in the external auditory canal. Histologically, it is a mixed tumor with epithelial and stromal parts of different proportions, and is recognized today by the World Health Organization (WHO) as a ceruminous adenoma. Similar to the pleomorphic adenoma of salivary glands, recurrence or malignant degeneration with cellular atypia and metastasis can occur on rare occasions. Here, we describe an 87-year old female patient with a growing spherical mass in the right external auditory canal. After exclusive endoscopic tumor resection, a ceruminous pleomorphic adenoma was histologically diagnosed. Due to the absence of nuclear pleomorphism, no increased mitotic rate, no perineural invasion and no fusion transcripts of the MYB or MYBL1 gene loci, an adenoid cystic carcinoma could be excluded. The postoperative course was without any evidence of complications. A literature review identified 44 articles with 49 patients that were considered. Hearing loss and ear sensations were the most commonly reported symptoms. Most cases underwent an excision via an endaural or retroauricular approach. Recurrences were described in four patients, three of which had a malignant transformation. View Full-Text
Keywords: Pleomorphic adenoma; external auditory canal; ceruminal gland tumor; ceruminous adenoma; endoscopic ear surgery Pleomorphic adenoma; external auditory canal; ceruminal gland tumor; ceruminous adenoma; endoscopic ear surgery
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Beckmann, S.; Dettmer, M.S.; Caversaccio, M.D.; Giger, R.; Anschuetz, L. Pleomorphic Adenoma of External Auditory Canal: Case Report of First Endoscopic Resection and Literature Review. Medicina 2020, 56, 248.

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