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Open AccessEditorial

New Strategies for Treatment of Sepsis

1
Internal Medicine Unit, Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy
2
Department of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario “A. Gemelli” IRCCS, 00168 Rome, Italy
*
Authors to whom correspondence should be addressed.
The Internal Medicine Sepsis Study Group: Stefano Carughi, Maria Maddalena D’Errico, Salvatore De Cosmo, Angela de Matthaeis, Michele Inglese, Antonio Pio Greco, Pamela Piscitelli, Laonardo Sacco (IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo), Tommaso Dionisi, Michele Impagnatiello, Giovanna Passaro, Mattia Paratore (Fondazione Policlinico Universitario “A. Gemelli” IRCCS, Rome), Carla Vincenza Vallone (Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi D’Aragona, Salerno), Vincenzo Zaccone (Azienda Ospedaliera Universitaria Ospedali Riuniti, Ancona).
Medicina 2020, 56(10), 527; https://doi.org/10.3390/medicina56100527
Received: 2 October 2020 / Accepted: 9 October 2020 / Published: 10 October 2020
(This article belongs to the Special Issue New Strategies for Treatment of Sepsis)
Sepsis represents a major global health concern and is one of the most feared complications for hospitalized patients, being the cause, directly or indirectly, of about half of all hospital deaths. According to the last definition, sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection and defined septic shock as a subset of sepsis in which underlying circulatory and cellular/metabolic abnormalities are profound enough to significantly increase mortality. Sepsis is a time-dependent disease and requires a prompt recognition and a standardized treatment. The Special Issue “New Strategies for Treatment of Sepsis” has been thought to connect the experience of physicians involved in the diagnosis, management, and treatment of sepsis at every stage of disease, from emergency departments to general and intensive wards. The focus will be pointed on new approaches to this syndrome, such as early recognition based on clinical features and biomarkers, management in non-ICUs, non-invasive treatment strategies, including non-antimicrobial agents, and, of course, invasive approaches. This Special Issue will highlight the many different facets of sepsis, seen through the eyes of different specialists. We hope to spread the knowledge of a new blueprint for treatment. View Full-Text
Keywords: internal medicine; intensive care; emergency department; organ dysfunction; immunomodulation; micronutrients; antimicrobial stewardship internal medicine; intensive care; emergency department; organ dysfunction; immunomodulation; micronutrients; antimicrobial stewardship
MDPI and ACS Style

Mirijello, A.; Tosoni, A.; on behalf of the Internal Medicine Sepsis Study Group. New Strategies for Treatment of Sepsis. Medicina 2020, 56, 527.

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