Next Article in Journal
Predictive Factors of Adrenal Insufficiency in Outpatients with Indeterminate Serum Cortisol Levels: A Retrospective Study
Next Article in Special Issue
Current Pharmacological Treatment of Painful Diabetic Neuropathy: A Narrative Review
Previous Article in Journal / Special Issue
Pain and Function in the Runner a Ten (din) uous Link
Open AccessArticle

Comparison of the Analgesic Effect of Ropivacaine with Fentanyl and Ropivacaine Alone in Continuous Epidural Infusion for Acute Herpes Zoster Management: A Retrospective Study

1
Department of Anesthesiology and Pain Medicine, Kyung Hee University Hospital, Kyungheedae Road 23, Dongdaemun-Gu, Seoul 02447, Korea
2
Department of Anesthesiology and Pain Medicine, Korea University Medical Center, Guro Hospital, Gurodong Road 148, Guro-Gu, Seoul 08308, Korea
*
Author to whom correspondence should be addressed.
Medicina 2020, 56(1), 22; https://doi.org/10.3390/medicina56010022
Received: 6 November 2019 / Revised: 19 December 2019 / Accepted: 6 January 2020 / Published: 8 January 2020
(This article belongs to the Special Issue Chronic Pain Management)
Background and Objectives: Currently, few studies have reported the effects of opioids during continuous epidural infusion (CEI) to control pain owing to herpes zoster (HZ). This study aimed to retrospectively compare the effectiveness of epidural opioids in the treatment of acute HZ pain. Materials and Methods: We reviewed medical records of 105 patients who were divided into two groups: R group (CEI with ropivacaine) and RF group (CEI with ropivacaine and fentanyl). Clinical efficacy was evaluated using the numeric rating scale (NRS) score for 6 months after the procedures. We compared the percentage of patients with complete remission in each group. We investigated the complication rates during CEI. Results: No significant differences in the NRS scores were observed between the two groups in the 6-month period. The adjusted odds ratio (OR) for patients included in the complete remission was 0.6 times lower in the RF group than in the R group (95% confidence interval: 0.22–1.71, p = 0.35). The OR for complications during CEI was higher in the RF group than in the R group. However, the difference was not statistically significant. Conclusions: No difference was observed in the management of HZ pain and the prevention of postherpetic neuralgia between the two groups. The incidence of complications tended to be higher in the RF group than in the R group. View Full-Text
Keywords: continuous epidural infusion; fentanyl; herpes zoster; ropivacaine; postherpetic neuralgia; neuropathic pain; intervention continuous epidural infusion; fentanyl; herpes zoster; ropivacaine; postherpetic neuralgia; neuropathic pain; intervention
Show Figures

Figure 1

MDPI and ACS Style

Kang, H.Y.; Lee, C.H.; Choi, S.S.; Lee, M.K.; Lee, Y.J.; Park, J.S. Comparison of the Analgesic Effect of Ropivacaine with Fentanyl and Ropivacaine Alone in Continuous Epidural Infusion for Acute Herpes Zoster Management: A Retrospective Study. Medicina 2020, 56, 22.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop