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Open AccessReview

Cardiovascular and Metabolic Consequences of Liver Transplantation: A Review

1
Faculty of Medicine, University of Medicine and Pharmacy “Carol Davila”, 050474 Bucharest, Romania
2
Gastroenterology Clinic, Clinical Emergency Hospital of Bucharest, 014461 Bucharest, Romania
3
Surgery Clinic, Clinical Emergency Hospital of Bucharest, 014461 Bucharest, Romania
4
Urology Clinic, Emergency University Central Military Hospital, 010242 Bucharest, Romania
5
Internal Medicine Clinic, Clinical Emergency Hospital of Bucharest, 014461 Bucharest, Romania
*
Author to whom correspondence should be addressed.
Medicina 2019, 55(8), 489; https://doi.org/10.3390/medicina55080489
Received: 19 May 2019 / Revised: 3 August 2019 / Accepted: 9 August 2019 / Published: 15 August 2019
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PDF [320 KB, uploaded 21 August 2019]

Abstract

Liver transplantation (LT) is considered the curative treatment option for selected patients who suffer from end-stage or acute liver disease or hepatic malignancy (primary). After LT, patients should be carefully monitored for complications that may appear, partially due to immunosuppressive therapy, but not entirely. Cardiovascular diseases are frequently encountered in patients with LT, being responsible for high morbidity and mortality. Patients with underlying cardiovascular and metabolic pathologies are prone to complications after the transplant, but these complications can also appear de novo, mostly associated with immunosuppressants. Metabolic syndrome, defined by obesity, hypertension, dyslipidemia, and hyperglycemia, is diagnosed among LT recipients and is aggravated after LT, influencing the long-term survival. In this review, our purpose was to summarize the current knowledge regarding cardiovascular (CV) diseases and the metabolic syndrome associated with LT and to assess their impact on short and long-term morbidity and mortality. View Full-Text
Keywords: liver transplantation; cardiovascular complications; metabolic consequences; hypertension; dyslipidemia liver transplantation; cardiovascular complications; metabolic consequences; hypertension; dyslipidemia
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Plotogea, O.; Ilie, M.; Sandru, V.; Chiotoroiu, A.; Bratu, O.; Diaconu, C. Cardiovascular and Metabolic Consequences of Liver Transplantation: A Review. Medicina 2019, 55, 489.

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