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Pulmonary Hypertension in COPD: A Case Study and Review of the Literature

Department of Pulmonary & Critical Care Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Author to whom correspondence should be addressed.
Medicina 2019, 55(8), 432;
Received: 31 May 2019 / Revised: 9 July 2019 / Accepted: 30 July 2019 / Published: 2 August 2019
(This article belongs to the Special Issue Case-Based Reviews in COPD)
Pulmonary hypertension (PH) is a frequently encountered complication of chronic obstructive pulmonary disease (COPD) and is associated with worsened clinical symptoms and prognosis. The prevalence of PH-COPD is not concretely established as classification criteria vary historically, but the presence of severe disease out of proportion to underlying COPD is relatively rare. Right heart catheterization, the gold standard in diagnosis of PH, is infrequently performed in COPD, and the overlap in the clinical symptoms of PH and COPD presents diagnostic challenges. Proven treatments are limited. Trials exploring the use of vasodilator therapy in this patient group generally demonstrate improvements in hemodynamics accompanied by worsening gas exchange without clearly demonstrated improvements in clinically meaningful outcomes. In-depth workup of underlying pulmonary hypertension and use of pulmonary vasodilator medications may be appropriate on an individual basis. We present a case study and a review and discussion of the pertinent literature on this topic. View Full-Text
Keywords: chronic obstructive pulmonary disease; pulmonary hypertension; PH-COPD chronic obstructive pulmonary disease; pulmonary hypertension; PH-COPD
MDPI and ACS Style

Cassady, S.J.; Reed, R.M. Pulmonary Hypertension in COPD: A Case Study and Review of the Literature. Medicina 2019, 55, 432.

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