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Open AccessArticle

The Influence of Bowel Preparation on ADC Measurements: Comparison between Conventional DWI and DWIBS Sequences

1
Children Clinical University Hospital, LV-1004 Riga, Latvia
2
Department of Diagnostic Radiology, Riga Stradin’s University, LV-1038 Riga, Latvia
3
Faculty of Medicine, Riga Stradin’s University, LV-1007 Riga, Latvia
4
Department of Internal Diseases, Riga Stradin’s University, LV-1038 Riga, Latvia
*
Author to whom correspondence should be addressed.
Medicina 2019, 55(7), 394; https://doi.org/10.3390/medicina55070394
Received: 5 June 2019 / Revised: 10 July 2019 / Accepted: 18 July 2019 / Published: 21 July 2019
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Abstract

Background and objectives: The aim of the study was to assess whether there were differences between apparent diffusion coefficient (ADC) values of diffusion-weighted imaging (DWI) and diffusion-weighted imaging with background body signal suppression (DWIBS) sequences in non-prepared and prepared bowels before and after preparation with an enteric hyperosmolar agent, to assess whether ADC measurements have the potential to avoid bowel preparation and whether ADC-DWIBS has advantages over ADC-DWI. Materials and Methods: 106 adult patients without evidence of inflammatory bowel disease (IBD) underwent magnetic resonance (MR) enterography before and after bowel preparation. ADC-DWI and ADC-DWIBS values were measured in the intestinal and colonic walls demonstrating high signal intensity (SI) at DWI tracking images of b = 800 s/mm2 before and after preparation. Results: There were significant difference (p < 0.0001) in both ADC-DWI and ADC-DWIBS results between non-prepared and prepared jejunum for DWI being 1.09 × 10−3 mm2/s and 1.76 × 10−3 mm2/s, respectively, and for DWIBS being 0.91 × 10−3 mm2/s and 1.75 × 10−3 mm2/s, respectively. Both ADC-DWI and DWIBS also showed significant difference between non-prepared and prepared colon (p < 0.0001), with DWI values 1.41 × 10−3 mm2/s and 2.13 × 10−3 mm2/s, and DWIBS—1.01 × 10−3 mm2/s and 2.04 × 10−3 mm2/s, respectively. No significant difference between ADC-DWI and ADC-DWIBS was found in prepared jejunum (p = 0.84) and prepared colon (p = 0.58), whereas a significant difference was found in non-prepared jejunum and non-prepared colon (p = 0.0001 in both samples). Conclusions: ADC between DWI and DWIBS does not differ in prepared bowel walls but demonstrates a difference in non-prepared bowel. ADC in non-prepared bowel is lower than in prepared bowel and possible overlap with the ADC range of IBD is possible in non-prepared bowel. ADC-DWIBS has no advantage over ADC-DWI in regard to IBD assessment. View Full-Text
Keywords: MR enterography; MRE; diffusion-weighted imaging; DWI; DWIBS; ADC MR enterography; MRE; diffusion-weighted imaging; DWI; DWIBS; ADC
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MDPI and ACS Style

Apine, I.; Baduna, M.; Pitura, R.; Pokrotnieks, J.; Krumina, G. The Influence of Bowel Preparation on ADC Measurements: Comparison between Conventional DWI and DWIBS Sequences. Medicina 2019, 55, 394.

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