Next Article in Journal
Antidiabetic Potential of Mangifera indica L. cv. Anwar Ratol Leaves: Medicinal Application of Food Wastes
Previous Article in Journal
Association of NOTCH3 Gene Polymorphisms with Ischemic Stroke and Its Subtypes: A Meta-Analysis
Article Menu

Export Article

Open AccessCase Report

Long Survival of a Patient with Trisomy 18 and Dandy-Walker Syndrome

1
Department of Pediatric of Federal, University of Rio Grande do Norte, Natal 58051-900, Brazil
2
Federal University of Rio Grande do Norte, Natal 58051-900, Brazil
*
Author to whom correspondence should be addressed.
Medicina 2019, 55(7), 352; https://doi.org/10.3390/medicina55070352
Received: 7 April 2019 / Revised: 1 July 2019 / Accepted: 2 July 2019 / Published: 8 July 2019
  |  
PDF [905 KB, uploaded 10 July 2019]
  |     |  

Abstract

Trisomy 18 is a genetic disease resulting from an extra chromosome 18, characterized by a broad clinical spectrum, poor prognosis and low rates of survival. This is the case of a 12 year-old girl diagnosed with full trisomy 18, and multiple malformations, including Dandy-Walker Syndrome and congenital heart defects on long term survival. At nine months, a new echocardiogram showed a double outlet right ventricle, significant pulmonary stenosis, patent ductus arteriosus and ventricular septal defect. Cardiac surgery was performed at one year and seven months. Early surgical intervention and multidisciplinary follow-up may change the clinical outcome of the disease. Further studies are required to evaluate the benefit of invasive procedures such as cardiac surgery on survival of patients with trisomy 18. View Full-Text
Keywords: trisomy 18; Edwards syndrome; aneuploidy; Dandy-Walker; long-term survival trisomy 18; Edwards syndrome; aneuploidy; Dandy-Walker; long-term survival
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Moura Ferreira de Souza, L.; Galvão e Brito Medeiros, A.; Ribeiro Júnior, J.P.; Nogueira de Melo, A.; Dias, S.A.M.M. Long Survival of a Patient with Trisomy 18 and Dandy-Walker Syndrome. Medicina 2019, 55, 352.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Medicina EISSN 1010-660X Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top