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Open AccessCase Report

Case Report of Misleading Features of a Rare Sertoli Cell Testicular Tumor

Vilnius City Clinical Hospital, Department of Urology, 10207 Vilnius, Lithuania
National Center of Pathology, Affiliate of Vilnius University Hospital, 08406 Vilnius, Lithuania
National Cancer Institute, Department of Chemotherapy, 08406 Vilnius, Lithuania
Authors to whom correspondence should be addressed.
Medicina 2019, 55(5), 170;
Received: 16 March 2019 / Revised: 16 April 2019 / Accepted: 14 May 2019 / Published: 20 May 2019
(This article belongs to the Special Issue Clinical Embryology and Reproductive Medicine)
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Testicular Sertoli cell tumors are extremely rare. Generally, they are benign neoplasms, which belong to a group called sex cord–stromal tumors. In this article, we present a case report of a Sertoli cell tumor, which was accidentally discovered during a urological consultation of a 42-year-old male. An ultrasound showed a 2.1 × 2.2 cm hypoechogenic, hypervascular tumor in the middle third of the left testicle. Serum tumor markers (α-fetoprotein, alkaline phosphatase, β-human chorionic gonadotropin, and lactic dehydrogenase) were all within the normal range. Rapid microscopic evaluation of fresh frozen sections during the operation was inconclusive, which led to a decision not to perform a radical orchiectomy immediately. On formalin-fixed paraffin-embedded (FFPE) sections, the tumor histology showed atypical patterns, and immunohistochemical analysis was performed in order to determine the type of neoplasm and differentiate it from other types of testicular tumors, so as to assign the further course of treatment. Radical inguinal orchiectomy was performed. The final pathology report showed a tumor with no predictive signs of aggressive behavior, which most closely resembled a Sertoli cell tumor. View Full-Text
Keywords: testicular tumor; Sertoli cell tumor testicular tumor; Sertoli cell tumor

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Anglickis, M.; Stulpinas, R.; Anglickienė, G.; Gabrilevičius, J.; Jaškevičius, A. Case Report of Misleading Features of a Rare Sertoli Cell Testicular Tumor. Medicina 2019, 55, 170.

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