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New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report

IRCCS Centro Neurolesi “Bonino-Pulejo”, 98123 Messina, Italy
Stroke Unit, Policlinico Universitario, 98123 Messina, Italy
Genovese Laboratory Medicine and Pathology, 98050 Barcellona PG, Italy
Author to whom correspondence should be addressed.
These authors equally contributed to this work.
Medicina 2019, 55(3), 71;
Received: 15 February 2019 / Revised: 7 March 2019 / Accepted: 14 March 2019 / Published: 17 March 2019
PDF [265 KB, uploaded 17 March 2019]


Ischemic stroke is a complex multifactorial disorder. Anticoagulation is a growing research area, with the main goal of preventing systemic embolization and stroke. We report the case of a 41-year-old woman with antiphospholipid syndrome who was unsuccessfully treated with Dabigatran, a new oral anticoagulant, as she developed a major stroke involving the right carotid artery, due to deep venous thrombosis with pulmonary embolism. We therefore suggest a closer monitoring of the safety and efficacy of dabigatran. Moreover, in the presence of multifactorial causes of pro-coagulation, we believe that warfarin should remain the mainstay of oral anticoagulation. View Full-Text
Keywords: dabigatran; warfarin; ischemic stroke; anticoagulants dabigatran; warfarin; ischemic stroke; anticoagulants
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Arcadi, F.A.; Portaro, S.; Giorgianni, R.; Naro, A.; Casella, C.; Genovese, C.; Marino, S.; Calabrò, R.S. New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report. Medicina 2019, 55, 71.

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