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Open AccessCase Report

An Atypical Case of Idiopathic Pulmonary Fibrosis in a Patient from Africa

1
Department of Respiratory Medicine and Allergy, Section of Respiratory Disease and Allergy, B4:09, Karolinska University Hospital, 171 76 Stockholm, Sweden
2
Respiratory Medicine Unit, Department of Medicine, Solna, Karolinska Institutet, 171 76 Stockholm, Sweden
3
Department of Pathology, Karolinska University Hospital, 171 76 Stockholm, Sweden
4
Department of Oncology-Pathology, Karolinska Institutet, 171 76 Stockholm, Sweden
*
Author to whom correspondence should be addressed.
Medicina 2019, 55(3), 67; https://doi.org/10.3390/medicina55030067
Received: 11 February 2019 / Accepted: 11 March 2019 / Published: 14 March 2019
(This article belongs to the Special Issue Idiopathic Pulmonary Fibrosis Research)
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Abstract

A 39 years old African man presented with fatigue, loss of weight and night sweats; radiology showed a possible usual interstitial pneumonia pattern. The patient missed follow-up visits, and presented again after 3 years with productive cough and general illness. Pulmonary function tests showed a decline of FVC compared to a previous investigation. The CT scans showed progression of the interstitial lung disease, and a multidisciplinary conference recommended to proceed with a surgical lung biopsy. Histopathology showed an atypical pattern, with bronchiolar metaplasia. A new multidisciplinary conference made a diagnosis of IPF, and the patient was treated with antifibrotic drugs with a good effect, reaching stability of lung function. This case report highlights the need to improve knowledge and to better characterize rare pulmonary diseases, and especially IPF, among African patients. View Full-Text
Keywords: idiopathic pulmonary fibrosis; antifibrotic treatment; peribronchiolar metaplasia idiopathic pulmonary fibrosis; antifibrotic treatment; peribronchiolar metaplasia
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Pesonen, I.; Ortiz, C.; Ferrara, G. An Atypical Case of Idiopathic Pulmonary Fibrosis in a Patient from Africa. Medicina 2019, 55, 67.

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