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A Patient with GOLD Stage 3 COPD « cured » by One-Way Endobronchial Valves

1
CHU-UCL-Namur, site Godinne, Université catholique de Louvain, Department of Pneumology, Institut de recherche expérimentale et Clinique (IREC), Av Dr Therasse 1, Yvoir, BE 5530, Belgium
2
Laboratoire de Physiologie Respiratoire, URPhyM, NARILIS, Faculté de Médecine, UNamur. Rue de Bruxelles, 61, Namur, BE 5000, Belgium
3
CHU-UCL-Namur, site Godinne, Université catholique de Louvain, Department of Pneumology, Av Dr Therasse 1, Yvoir - BELGIUM, BE 5530, Belgium
4
CHU-UCL-Namur, site Godinne, Department of Radiology, Av Dr Therasse 1, Yvoir , BE 5530, Belgium
*
Author to whom correspondence should be addressed.
Medicina 2019, 55(3), 65; https://doi.org/10.3390/medicina55030065
Received: 19 December 2018 / Revised: 14 February 2019 / Accepted: 4 March 2019 / Published: 11 March 2019
(This article belongs to the Special Issue Case-Based Reviews in COPD)
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Abstract

Lung hyperinflation is a main determinant of dyspnoea in patients with chronic obstructive pulmonary disease (COPD). Surgical or bronchoscopic lung volume reduction are the most efficient therapeutic approaches for reducing hyperinflation in selected patients with emphysema. We here report the case of a 69-year old woman with COPD (GOLD stage 3-D) referred for lung volume reduction. She complained of persistent disabling dyspnoea despite appropriate therapy. Chest imaging showed marked emphysema heterogeneity as well as severe hyperinflation of the right lower lobe. She was deemed to be a good candidate for bronchoscopic treatment with one-way endobronchial valves. In the absence of interlobar collateral ventilation, 2 endobronchial valves were placed in the right lower lobe under general anaesthesia. The improvement observed 1 and 3 months after the procedure was such that the patient no longer met the pulmonary function criteria for COPD. The benefit persisted after 3 years. View Full-Text
Keywords: COPD; treatment; lung hyperinflation; lung volume reduction; endobronchial valves COPD; treatment; lung hyperinflation; lung volume reduction; endobronchial valves
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Marchand, E.; d'Odemont, J.-P.; Dupont, M.V. A Patient with GOLD Stage 3 COPD « cured » by One-Way Endobronchial Valves. Medicina 2019, 55, 65.

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