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Open AccessReview

Effect of 2% Chlorhexidine Following Acid Etching on Microtensile Bond Strength of Resin Restorations: A Meta-Analysis

Stomatology Department, University of Valencia, 46010 Valencia, Spain
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Medicina 2019, 55(12), 769; https://doi.org/10.3390/medicina55120769
Received: 11 November 2019 / Revised: 26 November 2019 / Accepted: 27 November 2019 / Published: 2 December 2019
(This article belongs to the Section Dentistry)
Background and Objectives: The aim of this systematic review was to examine the effect of 2% chlorhexidine following acid etching on the microtensile bond strength of resin restorations for different follow-up times. Materials and Methods: A thorough search of PubMed, Scopus, and Embase databases were conducted. In vitro experimental studies or in vivo studies published up to December 2018 with an experimental group treated with a 2% chlorhexidine solution following acid etching and a control group were included, wherein the final restoration used a resin composite in both the groups. Results: Twenty-one articles were identified for qualitative analysis and 18 for meta-analysis. The difference in the means of microtensile bond strength between the two groups was calculated for the different follow-up times. The differences were significant for 6 months (4.30 MPa; 95% CI 2.72–5.89), 12 months (8.41 MPa; 95% CI 4.93–11.88), and 2–5 years including aged and thermocycling samples (9.08 MPa; 95% CI 5.36–12.81). There were no significant differences for the type of adhesive used. A meta-regression model showed a significant effect of time on the microtensile bond strength. Conclusions: The application of a 2% chlorhexidine solution after acid etching increased the microtensile bond strength significantly for follow-up times of 6 months or more. The adhesive type had no influence. View Full-Text
Keywords: chlorhexidine; microtensile bond strength; adhesion; dental adhesive; acid etching chlorhexidine; microtensile bond strength; adhesion; dental adhesive; acid etching
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Hamdan-Nassar, T.; Bellot-Arcís, C.; Paredes-Gallardo, V.; García-Sanz, V.; Pascual-Moscardó, A.; Almerich-Silla, J.M.; Montiel-Company, J.M. Effect of 2% Chlorhexidine Following Acid Etching on Microtensile Bond Strength of Resin Restorations: A Meta-Analysis. Medicina 2019, 55, 769.

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