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Open AccessArticle

Knowledge about Disease, Medication Therapy, and Related Medication Adherence Levels among Patients with Hypertension

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Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Rīga Stradiņš University, LV-1007 Riga, Latvia
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Department of Dosage Form Technology, Faculty of Pharmacy, Rīga Stradiņš University, LV-1007 Riga, Latvia
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Department of Public Health and Epidemiology, Faculty of Public Health and Welfare, Rīga Stradiņš University, LV-1010 Riga, Latvia
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Institute of Public Health, Rīga Stradiņš University, LV-1046 Riga, Latvia
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Author to whom correspondence should be addressed.
Medicina 2019, 55(11), 715; https://doi.org/10.3390/medicina55110715
Received: 25 June 2019 / Revised: 7 October 2019 / Accepted: 25 October 2019 / Published: 28 October 2019
Background and Objectives: A particular problem in cardiology is poor adherence to pharmacological treatment among patients with hypertension. It is known that approximately half of these patients do not use their medications as prescribed by their doctor. Patients may choose not to follow the doctor’s recommendations and regularly do not control their blood pressure, owing to many factors. A convenient method for measuring the level of adherence is the Morisky Medication Adherence Scale, which also provides insight into possible remedies for low adherence. We investigated their therapy, knowledge about the disease and its control, and demographic differences to assess the adherence of patients with hypertension. Materials and Methods: This was a cross-sectional observational study. Data were collected through a survey of 12 pharmacies in Latvia. The study involved 187 participants with hypertension. Results: The prevalence of non-adherence was 46.20% in Latvia. The oldest patients were the most adherent (p = 0.001, β = 0.27). The higher the self-rated extent from 0 to 10, to which the patient takes their antihypertensives exactly as instructed by their physician, the higher the level of adherence (p < 0.0001, β = 0.38), where at “0”, the patient does not follow physician instructions at all, and at “10”, the patient completely follows the physician’s instructions. Non-adherent patients tend to assess their medication-taking behavior more critically than adherent patients. The longer the patient is known to suffer from hypertension, the more adherent he or she is (p = 0.014, β = 0.19). Conclusions: Medication non-adherence among patients with hypertension is high in Latvia. Further investigations are needed to better understand the reasons for this and to establish interventions for improving patient outcomes. View Full-Text
Keywords: medication adherence; hypertension; questionnaire; Morisky Medication Adherence Scale medication adherence; hypertension; questionnaire; Morisky Medication Adherence Scale
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Gavrilova, A.; Bandere, D.; Rutkovska, I.; Šmits, D.; Mauriņa, B.; Poplavska, E.; Urtāne, I. Knowledge about Disease, Medication Therapy, and Related Medication Adherence Levels among Patients with Hypertension. Medicina 2019, 55, 715.

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