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Open AccessCase Report

A Case of Paraphilia with Osteoporosis and Administered with Depot Leuprorelin

Departments of Internal Medicine & Kinesiologic Medical Science, Dankook University, Cheonan 31116, Korea
Department of Psychiatry, College of Medicine, Dankook University, Cheonan 31116, Korea
Departments of Psychology & Psychotherapy, Environmental Health Center, College of Health Science, Dankook University, 119 Dandae-Rho, Dongnam-Gu, Cheonan 31116, Korea
Author to whom correspondence should be addressed.
Medicina 2019, 55(10), 705;
Received: 31 July 2019 / Revised: 7 October 2019 / Accepted: 17 October 2019 / Published: 20 October 2019
Paraphilia is a complex psychological and psychiatric disorder that has been difficult to treat. Leuprorelin has been used as one of the therapeutic methods for paraphilia. Leuprorelin administration could change insulin resistance and accelerate bone loss. The case study in this work was a 59-year-old man who visited a hospital with the chief complaints of frotteuristic behaviors in public places, a continuous increase in sexual desire, and sexual molestation behavior that started in 2007. We injected leuprorelin (3.6 mg) intramuscularly every month for this patient with paraphilia and comorbidities of osteoporosis and hyperthyroidism. The clinical global impression (CGI), Sex Addiction Screening Test (SAST), Wilson Sex Fantasy Questionnaire (WSFQ), physical examination, and laboratory tests were performed. After 12 months of leuprorelin injection for paraphilia, we found a significant improvement in abnormal sexual behavior/desire without aggravation of osteoporosis/hyperthyroidism. Gonadotrophin-Releasing Hormone (GnRH) analogs could be used as alternative or supplementary treatment methods for paraphilia with osteoporosis/hyperthyroidism. View Full-Text
Keywords: paraphilia; osteoporosis; hyperthyroidism; leuprorelin paraphilia; osteoporosis; hyperthyroidism; leuprorelin
MDPI and ACS Style

Kim, D.; Kim, K.M.; Lim, M.H. A Case of Paraphilia with Osteoporosis and Administered with Depot Leuprorelin. Medicina 2019, 55, 705.

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