Next Article in Journal
Physical Strength Perception of Older Caregivers in Rural Areas
Previous Article in Journal
Effectiveness of Warm-Up Routine on the Ankle Injuries Prevention in Young Female Basketball Players: A Randomized Controlled Trial
Open AccessArticle

Systemic and Local Factors’ Influence on the Topological Differences in Deep Vein Thrombosis

1
Department of Pharmacology, Toxicology and Clinical Pharmacology, “Iuliu Haţieganu” University of Medicine and Pharmacy, 400337 Cluj-Napoca, Romania
2
Department of Gastroenterology, 1st Medical Clinic, “Iuliu Haţieganu” University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania
3
Department of Internal Medicine, 1st Medical Clinic, “Iuliu Haţieganu” University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania
4
Department of Internal Medicine, 5th Medical Clinic, “Iuliu Haţieganu” University of Medicine and Pharmacy, 400139 Cluj-Napoca, Romania
5
Department of Medical Genetics, “Iuliu Haţieganu” University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania
*
Author to whom correspondence should be addressed.
Authors with equal contribution.
Medicina 2019, 55(10), 691; https://doi.org/10.3390/medicina55100691
Received: 26 September 2019 / Revised: 9 October 2019 / Accepted: 15 October 2019 / Published: 16 October 2019
Background and Objectives: Deep vein thrombosis (DVT) is a common cause of intra-hospital morbidity and mortality, and its most severe complication is pulmonary thromboembolism. The risk factors that influence the apparition of DVT are generally derived from Virchow’s triad. Since the most severe complications of DVT occur in proximal rather than distal deep vein thrombosis, the aim of this study was to identify the factors influencing the apparition of proximal DVT. Materials and Methods: This was a transversal, cohort study. The study included 167 consecutive patients with lower limb DVT over a two-year period. The following data were recorded or determined: general data, conditions that are known to influence DVT, medical history and coagulation or thrombophilia-related genetic variations. Results: In the univariate analysis, male gender, neoplasia, previous DVT and mutated factor V Leiden were all associated with proximal DVT, while bed rest was associated with distal DVT. In the multivariate analysis, male gender, previous DVT and factor V Leiden mutation were independently correlated with proximal DVT, while bed rest was independently associated with distal deep vein thrombosis. Conclusion: Our observations point out that the factors indicating a systemic involvement of coagulation were correlated with proximal DVT, while local factors were associated with distal DVT. View Full-Text
Keywords: deep vein thrombosis; risk factors; topological localization deep vein thrombosis; risk factors; topological localization
Show Figures

Figure 1

MDPI and ACS Style

Vesa, Ş.C.; Chira, R.; Vlaicu, S.I.; Pașca, S.; Crișan, S.; Trifa, A.; Buzoianu, A.D. Systemic and Local Factors’ Influence on the Topological Differences in Deep Vein Thrombosis. Medicina 2019, 55, 691.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop