Pollen-Food Allergy Syndrome: A not so Rare Disease in Childhood
Pediatric and Emergency Operative Unit, Policlinic Consortium University Hospital-Pediatric Hospital “Giovanni XXIII”, 70126 Bari, Italy
Pediatric Clinic, University Children’s Hospital, Medicine and Surgery Department, University of Parma, 43100 Parma, Italy
Pediatric Unit, Department of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy
Author to whom correspondence should be addressed.
Medicina 2019, 55(10), 641; https://doi.org/10.3390/medicina55100641
Received: 1 August 2019 / Revised: 18 September 2019 / Accepted: 20 September 2019 / Published: 26 September 2019
(This article belongs to the Special Issue Food Allergies)
Seasonal allergic rhinoconjunctivitis (SAR) affects millions of people worldwide, particularly in childhood and adolescence. Pollen food allergy syndrome (PFAS) is a common adverse reaction occurring few minutes after the consumption of vegetable foods in patients with pollen-induced SAR. PFAS has rarely been investigated in the pediatric population, as it has been mainly examined as an adult disease. Recent studies suggested that PFAS might be more frequent in childhood than previously recognized. The present review aims to give an overview of the epidemiology, pathophysiology, diagnosis, management and prognosis of PFAS in children with SAR-induced by pollens.