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Medicina 2018, 54(6), 106;

Parietaria Allergy: An Intriguing Challenge for the Allergist

Ospedale Policlinico San Martino, 16132 Genoa, Italy
Scientific, Pharmacovigilance and Regulatory Department Stallergenes-Greer, 20100 Milan, Italy
Cardiac/Pulmonary rehabilitation Unit, ASST Pini/CTO, 20100 Milan, Italy
Department of Otorhinolaryngology, Sapienza University, 00100 Rome, Italy
Author to whom correspondence should be addressed.
Received: 18 October 2018 / Revised: 5 December 2018 / Accepted: 5 December 2018 / Published: 7 December 2018
(This article belongs to the Special Issue Pollen Allergies)
PDF [266 KB, uploaded 7 December 2018]


Parietaria pollen is the most important cause of pollen allergies in the Mediterranean area, as Parietaria is widespread in this region. Many issues are associated with Parietaria allergy, including the duration of the pollen season (many doctors in fact believe that it lasts throughout the year), pollen load (which seems to be increasing over time), the impact of age (on IgE production and symptom severity), inflammatory changes (after pollen exposure), and the choice of allergen immunotherapy (AIT). In addition, molecular diagnostics allows for the defining of a correct diagnosis, differentiating between mere sensitization and true allergy. This review considers these topics and will hopefully help the allergist in clinical practice. Parietaria allergy is an intriguing challenge for the allergist in clinical practice, but it may be adequately managed by knowing the peculiarities of respective territories and the clinical characteristics of each patient.
Keywords: Parietaria; pollen; allergy; symptoms; inflammation; allergen immunotherapy Parietaria; pollen; allergy; symptoms; inflammation; allergen immunotherapy
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Ciprandi, G.; Puccinelli, P.; Incorvaia, C.; Masieri, S. Parietaria Allergy: An Intriguing Challenge for the Allergist. Medicina 2018, 54, 106.

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