Next Article in Journal
Novel Point Mutations in the NKX2.5 Gene in Pediatric Patients with Non-Familial Congenital Heart Disease
Previous Article in Journal
Incidence and Outcomes of Patients with Functionally Univentricular Heart Born in Latvia, 2007 to 2015
Open AccessReview

The Relationship between Vitamin D and Periodontal Pathology

1
Department of Dental and Oral Pathology, Medical Academy, Lithuanian University of Health Sciences, Eivenių 2, Kaunas LT-50161, Lithuania
2
AND Klinika, Žirmūnų 107, Vilnius LT-09116, Lithuania
3
Faculty of Medicine, Medical Academy, Lithuanian University of Health Sciences, A. Mickevičiaus 9, Kaunas LT-44307, Lithuania
*
Author to whom correspondence should be addressed.
Medicina 2018, 54(3), 45; https://doi.org/10.3390/medicina54030045
Received: 20 March 2018 / Revised: 4 June 2018 / Accepted: 8 June 2018 / Published: 12 June 2018
Osteoporosis and periodontal diseases are common problems among the elderly population. Vitamin D is a secosteroid hormone that is either synthesized by human skin cells under the effect of UV radiation or consumed through diet. Deficiency in vitamin D leads to reduced bone mineral density, osteoporosis, the progression of periodontal diseases and causes resorption to occur in the jawbone. Sufficient intake of vitamin D can decrease the risk of gingivitis and chronic periodontitis, as it has been shown to have immunomodulatory, anti-inflammatory, antiproliferative effects and initiates cell apoptosis. In addition, vitamin D is also important for bone metabolism, alveolar bone resorption and preventing tooth loss. It increases antibacterial defense of gingival epithelial cells and decrease gingival inflammation, improves postoperative wound healing after periodontal surgery and is an important supplement used as prophylaxis in periodontology. This publication aims to update the recent advances, stress the clinical importance, and evaluate vitamin D in the prevention of periodontal diseases to reach a successful outcome of conservative and surgical treatment. An analysis of the literature shows that vitamin D plays a significant role in maintaining healthy periodontal and jaw bone tissues, alleviating inflammation processes, stimulating post-operative healing of periodontal tissues and the recovery of clinical parameters. However, further research is needed to clarify the required vitamin D concentration in plasma before starting periodontal treatment to achieve the best outcome. View Full-Text
Keywords: osteoporosis; jaw; vitamin D deficiency; bone mineral density (BMD); 25-hydroxyvitamin D; serum levels osteoporosis; jaw; vitamin D deficiency; bone mineral density (BMD); 25-hydroxyvitamin D; serum levels
MDPI and ACS Style

Jagelavičienė, E.; Vaitkevičienė, I.; Šilingaitė, D.; Šinkūnaitė, E.; Daugėlaitė, G. The Relationship between Vitamin D and Periodontal Pathology. Medicina 2018, 54, 45.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop