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Open AccessArticle

Management of coronary artery disease patients in Latvia compared with practice in Central-Eastern Europe and globally: Analysis of the CLARIFY registry

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Latvian Centre of Cardiology, Pauls Stradins Clinical University Hospital, Riga, Latvia
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Research Institute of Cardiology, University of Latvia, Riga, Latvia
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Faculty of Medicine, University of Latvia, Riga, Latvia
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Riga Stradins University, Riga, Latvia
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Robertson Centre of Biostatistics, University of Glasgow, Glasgow, United Kingdom
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Department of Cardiology and LTTA Centre, University Hospital of Ferrara and Maria Cecilia Hospital, GVM Care & Research, E.S. Health Science Foundation, Cotignola, Italy
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INSERM U-1148 and University Paris Diderot, Paris, France
*
Author to whom correspondence should be addressed.
Medicina 2015, 51(4), 240-246; https://doi.org/10.1016/j.medici.2015.05.004
Received: 29 April 2014 / Accepted: 5 May 2015 / Published: 4 August 2015
Background and objective: Management of outpatients with stable coronary artery disease (CAD) is important in secondary prevention. The objective was to describe differences in the characteristics of CAD patients in Latvia compared with other countries.
Materials and methods: CLARIFY is an ongoing international, prospective, observational, longitudinal registry of outpatients with CAD. Data regarding treated outpatients with established CAD from the CLARIFY registry in Latvia (n = 120) were compared with those from the rest of Central-Eastern Europe (CEE) (n = 2888) and worldwide (n = 33,163).
Results: Patients in Latvia had a larger waist circumference (101 [95–109] vs. 99 [91–106] in CEE, 96.5 [88–105] cm worldwide; P = 0.023 and P < 0.001, respectively) and higher blood pressure (systolic: 138.28 ± 17.13 vs. 133.77 ± 16.47 in CEE and 130.97 ± 16.65 mm Hg worldwide, P = 0.003 and P < 0.001; diastolic: 82.98 ± 8.58 vs. 80.01 ± 9.61 in CEE and 77.22 ± 9.97 mm Hg worldwide, P < 0.001 and P < 0.001, respectively). Body mass index in Latvia did not differ significantly from that in CEE (P = 0.422), but was higher than worldwide (28.8 [26.2–32.0] vs. worldwide 27.3 [24.8–30.3] kg/m2, P < 0.001). The history of percutaneous coronary intervention was more frequent in Latvia (74.17% vs. 59.34% in CEE and 58.61% worldwide, P = 0.001 and P < 0.001, respectively). Latvian patients more frequently used aspirin (97.50% in Latvia vs. 89.75% in CEE and 87.64% worldwide, P = 0.005 and P = 0.001, respectively).
Conclusions: Latvian CAD patients are well managed in terms of aspirin use and frequency of percutaneous coronary intervention. Control of obesity and high BP is poorer and needs further improvement.
Keywords: Coronary artery disease; Latvia; Risk factors; Prevention Coronary artery disease; Latvia; Risk factors; Prevention
MDPI and ACS Style

Erglis, A.; Mintale, I.; Latkovskis, G.; Balode, I.; Jegere, S.; Bajare, I.; Rozenbergs, A.; Greenlaw, N.; Ferrari, R.; Steg, P.G.; , F.C. Management of coronary artery disease patients in Latvia compared with practice in Central-Eastern Europe and globally: Analysis of the CLARIFY registry. Medicina 2015, 51, 240-246.

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