Oral bony outgrowths: Prevalence and genetic factor influence. Study of twins
Materials and methods: In total, 162 twins (81 twin pairs) were analyzed for the presence or absence, type, and size of oral bony outgrowths. Statistical analysis was carried out to find the prevalence of bony protuberances and the relationship between zygosity and occurrence of oral bony enlargements. Zygosity of twins was confirmed by DNA analysis.
Results: 59.9% of the subjects had oral bony outgrowths. Mandibular tori were found in 56.8% and palatal tori in 1.8% of the sample. Palatal exostoses and mandibular exostoses were present in 1.8% and 3.1% of the sample, respectively, whereas maxillary exostoses were not found. A higher percentage of tori and exostoses were found in the group of older subjects (>18 years old, p = 0.025). No significant difference was found between men and women in the prevalence of bony outgrowths. High κ and r values (0.91 ± 0.062) showed very good concor-dance of oral bony outgrowths between monozygotic and moderate concordance (0.58 ± 0.141) between dizygotic co-twins ( p < 0.001). The calculation of heritability estimate verifies domi-nant influence of genetic factor on the etiology of oral bony outgrowths (h2 = 0.658).
Conclusion: The most common bony outgrowth was torus mandibularis. Our results show that the genetic factor is dominant in the etiology of oral bony outgrowths.
Auškalnis, A.; Bernhardt, O.; Putnienė, E.; Šidlauskas, A.; Andriuškevičiūtė, I.; Basevičienė, N. Oral bony outgrowths: Prevalence and genetic factor influence. Study of twins. Medicina 2015, 51, 228-232.
Auškalnis A, Bernhardt O, Putnienė E, Šidlauskas A, Andriuškevičiūtė I, Basevičienė N. Oral bony outgrowths: Prevalence and genetic factor influence. Study of twins. Medicina. 2015; 51(4):228-232.Chicago/Turabian Style
Auškalnis, Adomas; Bernhardt, Olaf; Putnienė, Eglė; Šidlauskas, Antanas; Andriuškevičiūtė, Irena; Basevičienė, Nomeda. 2015. "Oral bony outgrowths: Prevalence and genetic factor influence. Study of twins." Medicina 51, no. 4: 228-232.