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Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
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Comparison of the improvement in myocardial perfusion and function in cases of rapid and slow electrocardiographic stage dynamics between patients with TIMI-3 flow after primary angioplasty for acute myocardial infarction

Department of Internal Medicine, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
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Medicina 2015, 51(4), 217-221; https://doi.org/10.1016/j.medici.2015.04.003
Received: 6 January 2014 / Accepted: 13 April 2015 / Published: 5 August 2015
Background and objective: Post-PCI TIMI flow grade 3 in infarct-related artery not always is associated with follow-up improvement in myocardial perfusion and function. We compared the improvement in myocardial perfusion and function in cases of rapid and slow electrocardiographic (ECG) stage dynamics between patients with TIMI-3 flow after primary angioplasty for acute myocardial infarction (MI). Materials and methods: Ten patients with post-PCI TIMI-3 flow were divided into group A (n = 50, no rapid change of ECG stages) and group B (n = 50, with a ≥2 ECG stages per 2 days change rate). Results: There were no significant changes after 3 months in scintigraphic (ejection fraction 44.6 ± 9.3% vs. 42.0 ± 3.4%, P = 0.4; perfusion deficit severity 3.0 ± 0.7 vs. 2.3 ± 0.8, P = 0.1) and echocardiographic (dysfunction score 1.9 ± 0.2 vs. 1.6 ± 0.5, P = 0.2) data in group A. Scinti-graphic data improved (ejection fraction 34.6 ± 3.9% vs. 52.0 ± 7.3, P = 0.03; perfusion deficit severity 2.8 ± 0.6 vs. 1.5 ± 0.8, P = 0.03) and changes in echocardiographic data were of borderline significance (dysfunction score 1.8 ± 0.2 vs. 1.4 ± 0.4, P = 0.06) in group B. Conclusions: There was not any change in myocardial perfusion and function in a case of slow change of ECG stages after reached post-PCI TIMI flow grade 3, while myocardial perfusion improved and function tended to improve in a case of the rate at least two ECG stages in 2 days after primary angioplasty for acute MI.
Keywords: Electrocardiogram; Myocardial infarction; Percutaneous coronary intervention; Echocardiography; Tc-99m-sestamibi scintigraphy Electrocardiogram; Myocardial infarction; Percutaneous coronary intervention; Echocardiography; Tc-99m-sestamibi scintigraphy
MDPI and ACS Style

Kalinauskienė, E.; Naudžiūnas, A. Comparison of the improvement in myocardial perfusion and function in cases of rapid and slow electrocardiographic stage dynamics between patients with TIMI-3 flow after primary angioplasty for acute myocardial infarction. Medicina 2015, 51, 217-221.

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