Impact of etiology on course and outcomes of severe acute pancreatitis
Materials and methods: We investigated 81 patients with alcoholic and biliary SAP. Demographic data, etiologic factors, severity scores, intra-abdominal pressure, imaging studies, interventions, and treatment outcomes were prospectively entered into specially maintained database and subsequently analyzed.
Results: No statistically significant difference was observed in the prevalence of SAP in biliary and alcoholic AP groups (P = 0.429). Although, in the biliary SAP group patients were predominantly elderly women (P = 0.003), the total in-hospital stay was longer in alcoholic SAP patients (P = 0.021). The abdominal compartment syndrome developed more frequently (P = 0.041) and necrosectomy was more frequently performed in alcoholic SAP group (not statistically significant). Although not statistically significant, a lower mortality rate among biliary SAP patients (25.0% vs. 13.5%) was observed.
Conclusions: We defined a trend toward decreased incidence of infected necrosis in larger volume (≥30%) pancreatic necrosis, absence of abdominal compartment syndrome, lower rate of necrosectomies, shorter in-hospital stay, and an insignificantly reduced mortality rate in biliary SAP patients, indicating more favorable course of biliary SAP.
Barauskas, G.; Ignatavičius, P.; Vitkauskienė, A.; Pundzius, J.; Dambrauskas, Ž. Impact of etiology on course and outcomes of severe acute pancreatitis. Medicina 2015, 51, 167-172.
Barauskas G, Ignatavičius P, Vitkauskienė A, Pundzius J, Dambrauskas Ž. Impact of etiology on course and outcomes of severe acute pancreatitis. Medicina. 2015; 51(3):167-172.Chicago/Turabian Style
Barauskas, Giedrius; Ignatavičius, Povilas; Vitkauskienė, Astra; Pundzius, Juozas; Dambrauskas, Žilvinas. 2015. "Impact of etiology on course and outcomes of severe acute pancreatitis." Medicina 51, no. 3: 167-172.