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Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
Open AccessArticle

Evaluation of left ventricular longitudinal function and synchrony after dual chamber pacemaker implantation

1
Department of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
2
Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
*
Author to whom correspondence should be addressed.
Medicina 2014, 50(6), 340-344; https://doi.org/10.1016/j.medici.2014.11.010
Received: 28 May 2014 / Accepted: 18 November 2014 / Published: 28 November 2014
Background and objective: To evaluate left ventricular (LV) longitudinal function and dyssynchrony mechanisms after dual chamber pacemaker implantation.
Materials and methods: The speckle tracking imaging technique was used for quantification of global longitudinal function of the left ventricle and for dyssynchrony evaluation before pacemaker implantation and after 3-month follow-up. The study group consisted of 98 patients with conventional indications for dual chamber pacemaker implantation.
Results: Speckle tracking echocardiographic methods and image postprocessing revealed impairment of global longitudinal strain and significant LV dyssynchrony derived from 12 basal and mid-septum segments usually untraceable with conventional echocardiographic methods. Despite good physical performance and ejection fraction, global longitudinal strain significantly decreased in all patients from −15.08 ± 0.46 to −13.56 ± 0.5 (P < 0.05) as well as mitral annulus movement decreased from 11.57 ± 2.41 to 8.46 ± 1.74 cm/s (P < 0.001) and from 12.55 ± 2.75 to 10.78 ± 2.82 mm (P < 0.001). It was expected that patients with dual chamber pacemaker will develop inter- and intraventricular dyssynchrony, but our study showed that pacing lead position did not prevent from LV dysynchronisation and only changed the mechanism.
Conclusions: Global longitudinal strain and LV dyssynchrony assessment enables us to detect early signs of LV dysfunction. Mechanisms of dyssynchrony development will be useful for pacemaker programing choices in order to prevent further dyssynchronisation.
Keywords: Biomedical electronics; Dyssynchrony; Myocardial deformation imaging; Dual chamber pacemaker Biomedical electronics; Dyssynchrony; Myocardial deformation imaging; Dual chamber pacemaker
MDPI and ACS Style

Baronaitė-Dūdonienė, K.; Vaškelytė, J.; Puodžiukynas, A.; Zabiela, V.; Kazakevičius, T.; Šakalytė, G. Evaluation of left ventricular longitudinal function and synchrony after dual chamber pacemaker implantation. Medicina 2014, 50, 340-344.

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