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Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
Open AccessArticle

Impedance plethysmography as an alternative method for the diagnosis of peripheral arterial disease

1
Department of Internal Diseases, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
2
Institute of Physiology and Pharmacology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
*
Author to whom correspondence should be addressed.
Medicina 2014, 50(6), 334-339; https://doi.org/10.1016/j.medici.2014.11.007
Received: 11 April 2014 / Accepted: 21 November 2014 / Published: 27 November 2014
Background and objective: In the diagnosis of peripheral artery disease (PAD), the ankle-brachial index (ABI) is considered as the standard, and other noninvasive methods have received too little attention. Therefore, the aim of the study was to determine the diagnostic accuracy of impedance plethysmography in diagnosing PAD and to compare this method with other methods.
Materials and methods: A total of 66 patients with a mean age of 76.1 ± 9.6 years who had been treated for various cardiovascular diseases at Kaunas Clinical Hospital during 2011–2012 were enrolled into the study. All the patients were screened for PAD. Impedance plethysmography was performed with a new-generation NiccomoTM device. The receiver operating characteristic analysis was employed to determine the diagnostic accuracy of 4 parameters of impedance plethysmography: crest time (CT), crest width (CW), pulse amplitude (Pampl), and alternating blood flow (ABF).
Results: There were a significant correlation between the ABI and the CT (r = 0.699, P < 0.001), between the ABI and the ABF (r = 0.552; P < 0.001), and between the ABI and the Pampl only among men (r = 0.652; P < 0001). No correlation was found between the ABI and the CW. Among all the parameters, the CT had the highest sensitivity and specificity (73.2% and 96.0%, respectively). Other parameters had the following sensitivities and specificities: ABF, 61.0% and 96.0%; and Pampl, 90.0% and 20.0%, respectively.
Conclusions: Impedance plethysmography, especially its parameter CT, is an alternative non- invasive method in diagnosing PAD and could be used for the screening of patients with PAD.
Keywords: Impedance plethysmography; Ankle-brachial index; Peripheral arterial disease Impedance plethysmography; Ankle-brachial index; Peripheral arterial disease
MDPI and ACS Style

Mašanauskienė, E.; Sadauskas, S.; Naudžiūnas, A.; Unikauskas, A.; Stankevičius, E. Impedance plethysmography as an alternative method for the diagnosis of peripheral arterial disease. Medicina 2014, 50, 334-339.

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