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Medicina is published by MDPI from Volume 54 Issue 1 (2018). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Lithuanian Medical Association, Lithuanian University of Health Sciences, and Vilnius University.
Open AccessArticle

A new maximum color contrast sensitivity test for detecting early changes of visual function in age-related macular degeneration

1
Department of Ophthalmology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
2
Neuroscience Institute, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
*
Author to whom correspondence should be addressed.
Medicina 2014, 50(5), 281-286; https://doi.org/10.1016/j.medici.2014.10.008
Received: 9 January 2013 / Accepted: 7 September 2014 / Published: 1 November 2014
Background and objective: To determine the association between age-related macular degeneration (AMD) and color perception established by the Farnsworth–Munsell 100 hue (F–M 100) and maximum color contrast sensitivity (MCCS) tests.
Materials and methods: We performed a case–control study, which comprised of 100 patients with AMD and 100 healthy controls. To test visual acuity (VA), a typical Snellen chart was used. The computerized F–M 100 and MCCS programs were used for color discrimination.
Results: The results of VA, and the F–M 100 and MCCS tests in the healthy controls were statistically significantly better than in the patients with AMD (1.0 vs. 0.82 ± 0.16, P = 0.005; 87.39 ± 24.11 vs. 185.39 ± 74.43, P = 0.005; 1.33 ± 1.17 vs. 1.96 ± 0.46, P = 0.005, respectively). When VA was 1.0 in patients with AMD, the total error scores of the F–M 100 test and MCCS test compared with healthy persons were even worse (166.09 ± 66.57 vs. 87.39 ± 24.11, P = 0.002; 1.67 ± 0.92 vs. 1.33 ± 1.17, P = 0.001, respectively). Analysis of the results of patients with AMD compared to healthy controls showed the highest error score in the blue color range.
Conclusions: The results of the color contrast sensitivity test decreased by half in patients with AMD compared with ophthalmologically healthy patients when they performed the F–M 100 test and by one and half when they performed a MCCS test in the blue color range.
Keywords: Age-related macular degeneration; Color vision; Visual acuity; Farnsworth–Munsell 100 hue test Age-related macular degeneration; Color vision; Visual acuity; Farnsworth–Munsell 100 hue test
MDPI and ACS Style

Liutkevičienė, R.; Čebatorienė, D.; Žaliūnienė, D.; Lukauskienė, R.; Jašinskas, V. A new maximum color contrast sensitivity test for detecting early changes of visual function in age-related macular degeneration. Medicina 2014, 50, 281-286.

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